Výsledky vyhledávání - "Gairin Dancey"

Guidelines for information about therapy experiments: a proposal on best practice for recording experimental data on cancer therapy

Autor: Gairin Dancey, Alejandra Gonzalez-Beltran, May Y Yong, Richard H. J. Begent

Publikováno v: BMC Research Notes, Vol 5, Iss 1, p 10 (2012)
BMC Research Notes

Background Biology, biomedicine and healthcare have become data-driven enterprises, where scientists and clinicians need to generate, access, validate, interpret and integrate different kinds of experimental and patient-related data. Thus, recording

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e63fcc62982ebdfe500fecaf3d1259b
https://doi.org/10.1186/1756-0500-5-10

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A Phase I Clinical Trial of CHT-25 a 131I-Labeled Chimeric Anti-CD25 Antibody Showing Efficacy in Patients with Refractory Lymphoma

Autor: Philip Ross, Peter Amlot, Pei-San Chan, Christopher McNamara, Alan G. Ramsay, T. Andrew Lister, Alessandra Malaroda, Surinder K. Sharma, John R. Buscombe, Anmol Malhotra, Shokri Othman, Richard H. J. Begent, John Violet, Gairin Dancey, Roslyn J. Francis, Nicholas Woodward, Sweta Parker, Alan J. Green, Natalie Griffin

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 15(24)

Purpose: There is a need for new treatments for Hodgkin and T-cell lymphoma due to the development of drug resistance in a proportion of patients. This phase I study of radioimmunotherapy used CHT-25, a chimeric antibody to the α-chain of the interl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3576f9fa8b941a8801d61b10457bb499
https://pubmed.ncbi.nlm.nih.gov/20008855

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A phase I trial of radioimmunotherapy with 131I-A5B7 anti-CEA antibody in combination with combretastatin-A4-phosphate in advanced gastrointestinal carcinomas

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 15(13)

Purpose: In preclinical models, radioimmunotherapy with 131I-A5B7 anti–carcinoembryonic antigen (CEA) antibody (131I-A5B7) combined with the vascular disruptive agent combretastatin-A4-phosphate (CA4P) produced cures unlike either agent alone. We c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcbbc36929b7b3b91bacfe3e8154b7b7
http://ora.ox.ac.uk/objects/uuid:03bc90af-a61a-4d0e-8bd3-0374177a2972

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Imaging in targeted delivery of therapy to cancer

Autor: Richard H. J. Begent, Tim Meyer, Gairin Dancey

Publikováno v: Targeted oncology. 4(3)

We review the current status of imaging as applied to targeted therapy with particular focus on antibody-based therapeutics. Antibodies have high tumor specificity and can be engineered to optimize delivery to, and retention within, the tumor. Whole

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b70c5b809c0f5b5c676f827f0ffcb2c
https://pubmed.ncbi.nlm.nih.gov/19838639

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A tale of three Hs: HPV, HIVHAART

Autor: Mark Bower, Gairin Dancey, Justin Stebbing

Publikováno v: Future oncology (London, England). 2(1)

Justin Stebbing†, Gairin Dancey & Mark Bower †Author for correspondence Department of Oncology and HIV Medicine, The Chelsea and Westminster Hospital, 369 Fulham Road, London SW10 9NH, UK Tel.: +44 208 237 5054; Fax: +44 208 746 8863; j.stebbing@

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6b726d9643483df4854ec4fe04e510e
https://pubmed.ncbi.nlm.nih.gov/16556066

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