Transcriptome profiling of subepithelial PDGFRα cells in colonic mucosa reveals several cell-selective markers

Autor: Se Eun Ha, Byungchang Jin, Brian G. Jorgensen, Hannah Zogg, Lai Wei, Rajan Singh, Chanjae Park, Masaaki Kurahashi, Sei Kim, Gain Baek, Sandra M. Poudrier, Moon Young Lee, Kenton M. Sanders, Seungil Ro

Publikováno v: PLoS ONE, Vol 17, Iss 5 (2022)

Subepithelial platelet-derived growth factor receptor alpha (PDGFRα)+ cells found in the colonic mucosal tissue come in close contact with epithelial cells, immune cells, neurons, capillaries, and lymphatic networks. Mucosal subepithelial PDGFRα+ c

Externí odkaz: https://doaj.org/article/e0ce6f5c5dfc4d18818052ef84064da0

An Activatable AIEgen Probe for High‐Fidelity Monitoring of Overexpressed Tumor Enzyme Activity and Its Application to Surgical Tumor Excision

Autor: Haoying Ge, Gain Baek, Jeewon Chung, Dayeh Kim, Sang Jip Nam, Feng Xu, Juyoung Yoon, Prima F. Hillman, Xiaofeng Wu, Jiangli Fan, Yueqing Li, Eunyoung Lee, Haidong Li, Qichao Yao, Jingyun Wang, Xiaojun Peng

Publikováno v: Angewandte Chemie International Edition. 59:10186-10195

Monitoring fluctuations in enzyme overexpression facilitates early tumor detection and excision. An AIEgen probe (DQM-ALP) for the imaging of alkaline phosphatase (ALP) activity was synthesized. The probe consists of a quinoline-malononitrile (QM) co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208caa8735d9736481ceda37c092f222
https://doi.org/10.1002/anie.202001675

Metalloendopeptidase ADAM-like Decysin 1 (ADAMDEC1) in Colonic Subepithelial PDGFRα

Autor: Se Eun, Ha, Brian G, Jorgensen, Lai, Wei, Byungchang, Jin, Min-Seob, Kim, Sandra M, Poudrier, Rajan, Singh, Allison, Bartlett, Hannah, Zogg, Sei, Kim, Gain, Baek, Masaaki, Kurahashi, Moon-Young, Lee, Yong-Sung, Kim, Suck-Chei, Choi, Kent C, Sasse, Samuel J S, Rubin, Andres, Gottfried-Blackmore, Laren, Becker, Aida, Habtezion, Kenton M, Sanders, Seungil, Ro

Publikováno v: International journal of molecular sciences. 23(9)

Metalloendopeptidase ADAM-Like Decysin 1 (ADAMDEC1) is an anti-inflammatory peptidase that is almost exclusively expressed in the gastrointestinal (GI) tract. We have recently found abundant and selective expression of Adamdec1 in colonic mucosal PDG

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8595438da34ed0c056d68b0a647d5eee
https://pubmed.ncbi.nlm.nih.gov/35563399

Photoswitchable phthalocyanine-assembled nanoparticles for controlled 'double-lock' photodynamic therapy

Autor: Xingshu Li, Gain Baek, Nahyun Kwon, Hong-Bo Cheng, Juyoung Yoon, Yanyan Fang

Publikováno v: Chemical communications (Cambridge, England). 55(82)

In the current study, a new nanoparticle platform, NanoAzoPcS, is created by co-assembly of phthalocyanine and azobenzene amphiphiles, which can be used to gain precise control of PDT simply by regulating the stoichiometric ratio of the components an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3f730901feeead9621fc90b0cd32b22
https://pubmed.ncbi.nlm.nih.gov/31556410

miR-10a/b-5p-NCOR2 Regulates Insulin-Resistant Diabetes in Female Mice.

Autor: Ha, Se Eun¹ (AUTHOR) seeunh@med.unr.edu, Singh, Rajan¹ (AUTHOR) jin.jbc@gmail.com, Jin, Byungchang¹ (AUTHOR) gbaek@unr.edu, Baek, Gain¹ (AUTHOR) hannahphillips@unr.edu, Jorgensen, Brian G.¹ (AUTHOR) hansungp@unr.edu, Zogg, Hannah¹ (AUTHOR) suminc@unr.edu, Debnath, Sushmita¹ (AUTHOR), Park, Hahn Sung¹ (AUTHOR), Cho, Hayeong¹ (AUTHOR), Watkins, Claudia Marie¹ (AUTHOR), Cho, Sumin¹ (AUTHOR), Kim, Min-Seob² (AUTHOR) 1@wku.ac.kr, Lee, Moon Young² (AUTHOR) lmy6774@wku.ac.kr, Yu, Tae Yang³ (AUTHOR) endocrinology1@wku.ac.kr, Jeong, Jin Woo³ (AUTHOR) jinu84@wkuh.org, Ro, Seungil^1,4 (AUTHOR) sro@med.unr.edu

Publikováno v: International Journal of Molecular Sciences. Sep2024, Vol. 25 Issue 18, p10147. 19p.