Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Gail P. Mazzara"'
Autor:
Ashok Khatri, Bruce D. Walker, Eric S. Rosenberg, Gail P. Mazzara, Marylyn M. Addo, Gregory K. Robbins, Philip J. R. Goulder, Mary N. Philips, Christian Brander, Robert L. Eldridge, Kathleen Habeeb, Marcus Altfeld
The HIV-1 regulatory proteins Rev and Tat are expressed early in the virus life cycle and thus may be important targets for the immune control of HIV-1-infection and for effective vaccines. However, the extent to which these proteins are targeted in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2d0ab894ac2b836828e9b1fb57ee371
https://ora.ox.ac.uk/objects/uuid:64865adc-a49d-44e0-b546-2369c7f87c7a
https://ora.ox.ac.uk/objects/uuid:64865adc-a49d-44e0-b546-2369c7f87c7a
Autor:
Anna Aldovini, Deepti Aurora, Shainn Wei Wang, Mariana Manrique, Ewa Micewicz, Musie Ghebremichael, Keith G. Mansfield, Gail P. Mazzara, Pamela A. Kozlowski, Angela Carville, David C. Montefiori, Robert L. Wilson
Publikováno v:
AIDS Research and Human Retroviruses. 24:505-519
The ability of vaccines to induce immunity both in mucosal and systemic compartments may be required for prevention of HIV infection and AIDS. We compared DNA-MVA vaccination regimens adjuvanted by IL-12 DNA, administered intramuscularly and nasally
Autor:
Yue Sun, Valerie Philippon, Alicia Gomez-Yafal, Jenny G. Parvani, Norman L. Letvin, Phillip D. Markham, Michael S. Wyand, David C. Montefiori, Sampa Santra, Gail P. Mazzara, Dennis Panicali, Kelledy Manson
Publikováno v:
Journal of Virology. 81:8563-8570
As the diversity of potential immunogens increases within certain classes of vectors, the possibility has arisen of employing heterologous prime/boost immunizations using diverse members of the same family of vectors. The present study was initiated
Autor:
Kimberly A. Zinnack, Norman L. Letvin, Kristin Beaudry, Alicia Gómez Yafal, Petr O. Ilyinskii, Dennis Panicali, Kelledy Manson, Shawn S. Jackson, Valerie Philippon, Marcelo J. Kuroda, Linda Gritz, Michelle A. Lifton, Gail P. Mazzara
Publikováno v:
Journal of Virology. 79:6554-6559
Poxvirus vaccine vectors, although capable of eliciting potent immune responses, pose serious health risks in immunosuppressed individuals. We therefore constructed five novel recombinant vaccinia virus vectors which contained overlapping deletions o
Autor:
Herman F. Staats, Alicia Gómez Yafal, Sushila K. Nordone, Norman L. Letvin, Barton F. Haynes, Hua-Xin Liao, Shawn S. Jackson, James W. Peacock, Linda Gritz, Gail P. Mazzara
Publikováno v:
Journal of Virology. 78:13163-13172
Induction of mucosal anti-human immunodeficiency virus type 1 (HIV-1) T-cell responses in males and females will be important for the development of a successful HIV-1 vaccine. An HIV-1 envelope peptide, DNA plasmid, and recombinant modified vaccinia
Autor:
Pamela A. Kozlowski, Lara Herrmann, Angela Carville, Anna Aldovini, Mike Piatak, R. Paul Johnson, Shainn Wei Wang, Frederic M.N. Bertley, Gail P. Mazzara, Keith G. Mansfield, Kelledy Manson
Publikováno v:
AIDS Research and Human Retroviruses. 20:846-859
We explored the use of a simian-human immunodeficiency virus (SHIV) DNA vaccine as an effective mucosal priming agent to stimulate a protective immune response for AIDS prevention. Rhesus macaques were vaccinated rectally with a DNA construct produci
Autor:
Gail P. Mazzara, Antonia Radaelli, Yvette Edghill-Smith, Wen Po Tsai, Elzbieta Tryniszewska, Veronica Elli, Carlo De Giuli Morghen, Phil Markham, Dennis Panicali, David Venzon, Carlo Zanotto, Genoveffa Franchini, Janos Nacsa
Publikováno v:
Virology. 312:181-195
A therapeutic vaccine for individuals infected with HIV-1 and treated with antiretroviral therapy (ART) should be able to replenish virus-specific CD4+ T-cells and broaden the virus-specific CD8+ T-cell response in order to maintain CD8+ T-cell funct
Autor:
M. L. Kalish, Kelledy Manson, Michael S. Wyand, S. L. Lydy, James G. Herndon, David C. Montefiori, Harriet L. Robinson, Harold M. McClure, Shan Lu, R P Johnson, Tahir A. Rizvi, M A Candido, J. D. Lifson, Dennis Panicali, Rhona L. Glickman, Shiu Lok Hu, Gail P. Mazzara
Publikováno v:
Nature Medicine. 5:526-534
Eight different protocols were compared for their ability to raise protection against immunodeficiency virus challenges in rhesus macaques. The most promising containment of challenge infections was achieved by intradermal DNA priming followed by rec
Autor:
John C. Kunich, Haynes W. Sheppard, Susan E. Wilson, Victoria L. Wilkins, Shannon L. Pedersen, James Tartaglia, Gail P. Mazzara, Dean L. Mann, Connie Celum
Publikováno v:
AIDS Research and Human Retroviruses. 14:925-937
A major objective of current HIV-1 vaccination strategies is the induction of HIV-1-specific CD8+ MHC class I-restricted CTL responses, which are suggested to play a pivotal role in viral clearance and protection against HIV-1 disease progression. Ho
Autor:
Georgia D. Tomaras, Paul A. Goepfert, Michael Pensiero, Lawrence Corey, Valerie Philippon, Paulo Feijó Barroso, Massimo Cardinali, Marnie Elizaga, Barbara Metch, Xia Jin, David C. Montefiori, M. Juliana McElrath, Michael C. Keefer, Stephen C. De Rosa, Dennis Panicali, Gail P. Mazzara, Guido Ferrari, Olivier D. Defawe, Artur Kalichman, Sharon E. Frey
We evaluated replication-defective poxvirus vectors (modified vaccinia Ankara [MVA] and fowlpox [FPV]) in a homologous and heterologous vector prime-boost vaccination regimen containing matching HIV inserts (MVA-HIV and FPV-HIV) given at months 0, 1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::059e70ae901f17cd347d1e91203907b1
https://europepmc.org/articles/PMC3043112/
https://europepmc.org/articles/PMC3043112/