Zobrazeno 1 - 10
of 495
pro vyhledávání: '"Gail P Jarvik"'
Autor:
J William Gaynor, Nancy B Burnham, Richard F Ittenbach, Marsha Gerdes, Judy C Bernbaum, Elaine Zackai, Daniel J Licht, William W Russell, Erin E Zullo, Thomas Miller, Hakon Hakonarson, Kayan A Clarke, Gail P Jarvik, Antonia M Calafat, Asa Bradman, David C Bellinger, Frederick M Henretig, Eric S Coker
Publikováno v:
PLoS ONE, Vol 17, Iss 11, p e0277611 (2022)
BackgroundChildren with congenital heart defects have an increased risk of neurodevelopmental disability. The impact of environmental chemical exposures during daily life on neurodevelopmental outcomes in toddlers with congenital heart defects is unk
Externí odkaz:
https://doaj.org/article/06a8d83974c74554b641122c2e4fea23
Autor:
Alexandra S Shadrina, Elizaveta E Elgaeva, Ian B Stanaway, Gail P Jarvik, Bahram Namjou, Wei-Qi Wei, Joe Glessner, Hakon Hakonarson, Pradeep Suri, Yakov A Tsepilov
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0268725 (2022)
Varicose veins of lower extremities (VVs) are a highly prevalent condition, the pathogenesis of which is still not fully elucidated. Mendelian randomization (MR) can provide useful preliminary information on the traits that are potentially causally r
Externí odkaz:
https://doaj.org/article/191b459206f547cc870a0c4d20c50fa4
Autor:
Rui Li, Peiyi Gao, Jie Sun, Hiroko Watase, Xihai Zhao, Mi Shen, Binbin Sui, Niranjan Balu, Gail P Jarvik, Thomas S Hatsukami
Publikováno v:
Stroke and Vascular Neurology, Vol 6, Iss 1 (2021)
Background and purpose While extracranial carotid artery stenosis is more common among Caucasians and intracranial artery stenosis is more common among Asians, the differences in atherosclerotic plaque characteristics have not yet been extensively ex
Externí odkaz:
https://doaj.org/article/c4f12951f67446ffad7431953b721a95
Autor:
Yao Hu, Mariaelisa Graff, Jeffrey Haessler, Steven Buyske, Stephanie A Bien, Ran Tao, Heather M Highland, Katherine K Nishimura, Niha Zubair, Yingchang Lu, Marie Verbanck, Austin T Hilliard, Derek Klarin, Scott M Damrauer, Yuk-Lam Ho, VA Million Veteran Program, Peter W F Wilson, Kyong-Mi Chang, Philip S Tsao, Kelly Cho, Christopher J O'Donnell, Themistocles L Assimes, Lauren E Petty, Jennifer E Below, Ozan Dikilitas, Daniel J Schaid, Matthew L Kosel, Iftikhar J Kullo, Laura J Rasmussen-Torvik, Gail P Jarvik, Qiping Feng, Wei-Qi Wei, Eric B Larson, Frank D Mentch, Berta Almoguera, Patrick M Sleiman, Laura M Raffield, Adolfo Correa, Lisa W Martin, Martha Daviglus, Tara C Matise, Jose Luis Ambite, Christopher S Carlson, Ron Do, Ruth J F Loos, Lynne R Wilkens, Loic Le Marchand, Chris Haiman, Daniel O Stram, Lucia A Hindorff, Kari E North, Charles Kooperberg, Iona Cheng, Ulrike Peters
Publikováno v:
PLoS Genetics, Vol 16, Iss 3, p e1008684 (2020)
Lipid levels are important markers for the development of cardio-metabolic diseases. Although hundreds of associated loci have been identified through genetic association studies, the contribution of genetic factors to variation in lipids is not full
Externí odkaz:
https://doaj.org/article/ca40beb39a0e40c49b79df873ea4e1d6
Autor:
Pradeep Suri, Melody R Palmer, Yakov A Tsepilov, Maxim B Freidin, Cindy G Boer, Michelle S Yau, Daniel S Evans, Andrea Gelemanovic, Traci M Bartz, Maria Nethander, Liubov Arbeeva, Lennart Karssen, Tuhina Neogi, Archie Campbell, Dan Mellstrom, Claes Ohlsson, Lynn M Marshall, Eric Orwoll, Andre Uitterlinden, Jerome I Rotter, Gordan Lauc, Bruce M Psaty, Magnus K Karlsson, Nancy E Lane, Gail P Jarvik, Ozren Polasek, Marc Hochberg, Joanne M Jordan, Joyce B J Van Meurs, Rebecca Jackson, Carrie M Nielson, Braxton D Mitchell, Blair H Smith, Caroline Hayward, Nicholas L Smith, Yurii S Aulchenko, Frances M K Williams
Publikováno v:
PLoS Genetics, Vol 14, Iss 9, p e1007601 (2018)
Back pain is the #1 cause of years lived with disability worldwide, yet surprisingly little is known regarding the biology underlying this symptom. We conducted a genome-wide association study (GWAS) meta-analysis of chronic back pain (CBP). Adults o
Externí odkaz:
https://doaj.org/article/e7405eec3ba84a9f9ddf6c053f265a3f
Autor:
Logan Dumitrescu, Marylyn D Ritchie, Joshua C Denny, Nihal M El Rouby, Caitrin W McDonough, Yuki Bradford, Andrea H Ramirez, Suzette J Bielinski, Melissa A Basford, High Seng Chai, Peggy Peissig, David Carrell, Jyotishman Pathak, Luke V Rasmussen, Xiaoming Wang, Jennifer A Pacheco, Abel N Kho, M Geoffrey Hayes, Martha Matsumoto, Maureen E Smith, Rongling Li, Rhonda M Cooper-DeHoff, Iftikhar J Kullo, Christopher G Chute, Rex L Chisholm, Gail P Jarvik, Eric B Larson, David Carey, Catherine A McCarty, Marc S Williams, Dan M Roden, Erwin Bottinger, Julie A Johnson, Mariza de Andrade, Dana C Crawford
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171745 (2017)
Resistant hypertension is defined as high blood pressure that remains above treatment goals in spite of the concurrent use of three antihypertensive agents from different classes. Despite the important health consequences of resistant hypertension, f
Externí odkaz:
https://doaj.org/article/b002153fafa945a8b48317afbc1af625
Autor:
Bahram Namjou, Keith Marsolo, Todd Lingren, Marylyn D Ritchie, Shefali S Verma, Beth L Cobb, Cassandra Perry, Terrie E Kitchner, Murray H Brilliant, Peggy L Peissig, Kenneth M Borthwick, Marc S Williams, Jane Grafton, Gail P Jarvik, Ingrid A Holm, John B Harley
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138677 (2015)
Liver enzyme levels and total serum bilirubin are under genetic control and in recent years genome-wide population-based association studies have identified different susceptibility loci for these traits. We conducted a genome-wide association study
Externí odkaz:
https://doaj.org/article/c8cce4ea591b4fc78e631c42b28f19ce
Autor:
Shefali S Verma, Mariza ede Andrade, Gerard eTromp, Helena eKuivaniemi, Elizabeth ePugh, Bahram eNamjou, Shubhabrata eMukherjee, Gail P Jarvik, Leah Claire Kottyan, Amber eBurt, Yuki eBradford, Gretta D Armstrong, Kimberly eDerr, Dana eCrawford, Jonathan L Haines, Rongling eLi, David eCrosslin, Marylyn D Ritchie
Publikováno v:
Frontiers in Genetics, Vol 5 (2014)
The electronic MEdical Records and GEnomics (eMERGE) network brings together DNA biobanks linked to electronic health records (EHRs) from multiple institutions. Approximately 52,000 DNA samples from distinct individuals have been genotyped using geno
Externí odkaz:
https://doaj.org/article/9c288e9d83ef482bbea86a5c0236ebb4
Autor:
Robert Michael Cronin, Julie R Field, Yuki eBradford, Christian M Shaffer, Robert J Carroll, Jonathan D Mosley, Lisa eBastarache, Todd L Edwards, Scott J Hebbring, Simon eLin, Lucia A Hindorff, Paul K Crane, Sarah ePendergrass, Marylyn D Ritchie, Dana C Crawford, Jyotishman ePathak, Suzette eBielinski, David S Carrell, David R Crosslin, David H Ledbetter, David J Carey, Gerard eTromp, Marc S Williams, Eric B Larson, Gail P Jarvik, Peggy L Peissig, Murray H Brilliant, Catherine Anne McCarty, Christopher G Chute, Iftikhar J Kullo, Erwin eBottinger, Rex eChisholm, Maureen E Smith, Dan M Roden, Joshua C Denny
Publikováno v:
Frontiers in Genetics, Vol 5 (2014)
Phenome-wide association studies (PheWAS) have demonstrated utility in validating genetic associations derived from traditional genetic studies as well as identifying novel genetic associations. Here we used an electronic health record (EHR)-based Ph
Externí odkaz:
https://doaj.org/article/0ab6e1db8b1b479ea15406e8958cb57a
Autor:
John J Connolly, Joseph T Glessner, Berta eAlmoguera, David R Crosslin, Gail P Jarvik, Patrick eSleiman, Hakon eHakonarson
Publikováno v:
Frontiers in Genetics, Vol 5 (2014)
The goal of this paper is to review recent research on copy number variations (CNVs) and their association with complex and rare diseases. In the latter part of this paper, we focus on how large biorepositories such as the electronic medical record a
Externí odkaz:
https://doaj.org/article/f686a7bc1df84596bcb69792480812b8