Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Gail M. Nelson"'
Autor:
Gail M. Nelson, Brian N. Chorley
Publikováno v:
Genomic and Epigenomic Biomarkers of Toxicology and Disease. :7-35
Autor:
Matthew C. Cave, Christina M. Pinkston, Shesh N. Rai, Banrida Wahlang, Marian Pavuk, Kimberly Z. Head, Gleta K. Carswell, Gail M. Nelson, Carolyn M. Klinge, Douglas A. Bell, Linda S. Birnbaum, Brian N. Chorley
Publikováno v:
Environmental Health Perspectives
Background: Polychlorinated biphenyl (PCB) exposures have been associated with liver injury in human cohorts, and steatohepatitis with liver necrosis in model systems. MicroRNAs (miRs) maintain cellular homeostasis and may regulate the response to en
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 7, Iss, Pp 805-815 (2020)
Toxicology Reports, Vol 7, Iss, Pp 805-815 (2020)
MicroRNAs (miRNAs) are short non-coding RNA species that play key roles in post-transcriptional regulation of gene expression. MiRNAs also serve as a promising source of early biomarkers for different environmental exposures and health effects, altho
Autor:
Leah C. Wehmas, Charles E. Wood, Gail M. Nelson, Susan D. Hester, Carole L. Yauk, Brian N. Chorley
Publikováno v:
Toxicol Sci
Formalin-fixed paraffin-embedded (FFPE) tissues provide an important resource for toxicogenomic research. However, variability in the integrity or quality of RNA obtained from archival FFPE specimens can lead to unreliable data and wasted resources,
Autor:
Samantha J. Snow, Kymberly M. Gowdy, Myles X Hodge, Andres R. Henriquez, Haiyan Tong, Brian N. Chorley, Judy E. Richards, Mette C. Schladweiler, Virgina Bass, Allen D. Ledbetter, Wan-Yun Cheng, Urmila P. Kodavanti, Gail M. Nelson, Gleta Carswell
Publikováno v:
Toxicological Sciences. 163:57-69
Fish, olive, and coconut oil dietary supplementation have several cardioprotective benefits, but it is not established if they protect against air pollution-induced adverse effects. We hypothesized that these dietary supplements would attenuate ozone
Publikováno v:
Journal of Visualized Experiments : JoVE
New technologies that utilize capillary-based immunoassays promise faster and more quantitative protein assessment compared to traditional immunoassays. However, similar to other antibody-based protein assays, optimization of capillary-based immunoas
Autor:
Gail M. Nelson, Christina Pinkston, Heather B. Clair, Matthew C. Cave, Brian N. Chorley, Marian Pavuk, Gleta Carswell, Shesh N. Rai
Publikováno v:
Gastroenterology. 154:S-1204
Autor:
Gail M. Nelson, Kirk T. Kitchin, Gene J. Ahlborn, James W. Allen, Hongzu Ren, Bhalchandra A. Diwan, J. Christopher Corton, Geremy Knapp, Don A. Delker, Michael P. Waalkes
Publikováno v:
Toxicology
Exposure of male C3H mice in utero (from gestational days 8–18) to 85 ppm sodium arsenite via the dams’ drinking water has previously been shown to increase liver tumor incidence by 2 years of age. However, in our companion study (Ahlborn et al.,
Autor:
Thomas G. O'Brien, Michael J. Kohan, William O. Ward, Don A. Delker, James W. Allen, Barbara C. Roop, Gail M. Nelson, Kirk T. Kitchin, Yan Chen, Gene J. Ahlborn
Publikováno v:
Toxicology. 241:134-145
Chronic arsenic exposure in humans is associated with cancers of the skin, lung, bladder and other tissues. There is evidence that folate deficiency may increase susceptibility to arsenic effects, including skin lesions. K6/ODC mice develop skin tumo
Autor:
Tanya Moore, Sheau-Fung Thai, Michael H. George, Gail M. Nelson, Carlton P. Jones, Julie R. Thibodeaux, Susan D. Hester, Guobin Sun, Ernest Winkfield, James W. Allen, Sharon Leavitt, Douglas C. Wolf, Stephen Nesnow, Barbara C. Roop, Don A. Delker
Publikováno v:
Toxicologic Pathology. 34:895-902
Conazoles are a class of azole based fungicides used in agriculture and as pharmaceutical products. They have a common mode of antifungal action through inhibition of ergosterol biosynthesis. Some members of this class have been shown to be hepatotox