Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Gail M. Johnson"'
Autor:
Bruce C. MacDonald, M. D. Likar, Gail M. Johnson, Sophia C. Carroll, Thean Yeoh, Stephen T. Colgan, J. Sean Space
Publikováno v:
Journal of pharmaceutical sciences. 107(12)
Hard gelatin capsule (HGC) shells are widely used to encapsulate drugs for oral delivery but are vulnerable to gelatin cross-linking, which can lead to slower and more variable in vitro dissolution rates. Adding proteolytic enzymes to the dissolution
Autor:
Gaurav Bharadwaj, Katrina M. Miranda, Patricia G.Z. Benini, Cyf Ramos-Colon, Larry K. Keefer, Gail M. Johnson, Daniela Andrei, Marti Larriva, Debashree Basudhar
Publikováno v:
Nitric Oxide. 42:70-78
Nitroxyl (HNO) donors have been shown to elicit a variety of pharmacological responses, ranging from tumoricidal effects to treatment of heart failure. Isopropylamine-based diazeniumdiolates have been shown to produce HNO on decomposition under physi
Autor:
Gail M. Johnson, Sophia C. Carroll, Bruce C. MacDonald, M. D. Likar, James F. Jensen, Vincent DeMatteo, Todd Zelesky, Joel M. Hawkins, J. Sean Space, Stephen T. Colgan, Raymond Chen
Publikováno v:
Journal of pharmaceutical sciences. 105(7)
Formaldehyde and formic acid are reactive impurities found in commonly used excipients and can be responsible for limiting drug product shelf-life. Described here is the use of activated carbon in drug product packaging to attenuate formaldehyde-indu
Autor:
Katrina M. Miranda, Tyler J. Chozinski, Elyssia S. Gallagher, Craig A. Aspinwall, Gail M. Johnson
Nitroxyl (HNO) donors exhibit promising pharmacological characteristics for treatment of cardiovascular disorders, cancer, and alcoholism. However, whether HNO also serves as an endogenous signaling agent is currently unknown, largely because of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cdca1c96f7baf7119fb39e8544aa287
https://europepmc.org/articles/PMC4254043/
https://europepmc.org/articles/PMC4254043/
Autor:
Gail M. Johnson, Tyler J. Chozinski, Alan D. Moghaddam, Katrina M. Miranda, Hsin Chih Chen, Debra J. Salmon
Publikováno v:
Free radical biologymedicine. 63
Donors of nitroxyl (HNO) have shown promise for treatment of stroke, heart failure, alcoholism and cancer. However, comparing the pharmacological capacities of various donors is difficult without first quantifying the amount of HNO released from each
Autor:
Katrina M. Miranda, Hsin Chih Chen, Debra J. Salmon, Alan D. Moghaddam, Tyler J. Chozinski, Gail M. Johnson
Publikováno v:
Free Radical Biology and Medicine. 77:390