Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Gail Lawrance"'
Publikováno v:
European Journal of Neuroscience. 19:2903-2908
This study examined the effects of hypomorphic p75 neurotrophin receptor (p75NTR) expression and high levels of nerve growth factor (NGF) on trkA phosphorylation and downstream activation of p44/42 mitogen-activated protein kinase (MAPK). Post-gangli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d49f8e83efd55fd9800ce2e4ea45f8
https://doi.org/10.1111/j.0953-816x.2004.03381.x
https://doi.org/10.1111/j.0953-816x.2004.03381.x
Autor:
R.J. Rylett, Robert J. Dunn, Kimberly Dow, Richard J. Riopelle, Gail Lawrance, P. M. Richardson
Publikováno v:
Journal of Neurochemistry. 64:1483-1490
In the human neuroblastoma cell line LA-N-2, recombinant rat ciliary neurotrophic factor (CNTF) induced neurite growth and cholinergic differentiation that were both half-maximally saturated at < 100 pM of the neurokine, but was not required for cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::606aa92ad34d1f22d6f9d0c1a6440243
https://doi.org/10.1046/j.1471-4159.1995.64041483.x
https://doi.org/10.1046/j.1471-4159.1995.64041483.x
Autor:
Richard J. Riopelle, Valerie M. K. Verge, D. H. Maurice, Wei Wang, Kimberly Dow, P. M. Richardson, Gail Lawrance, L. H. Zinman
Publikováno v:
Journal of Neurochemistry. 70:1411-1420
We have probed the molecular basis of functional effects of ciliary neurotrophic factor (CNTF) and nerve growth factor (NGF) on aspects of the neuronal differentiation of LA-N-2 neuroblastoma cells. The influence of CNTF on the cholinergic phenotype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15c4122c6f9857efabdc41992b43c1ef
https://doi.org/10.1046/j.1471-4159.1998.70041411.x
https://doi.org/10.1046/j.1471-4159.1998.70041411.x
Autor:
Kimberly Dow, Wei Wang, Richard J. Riopelle, Gail Lawrance, Gregory M. Ross, Suzanne M. Dostaler
Publikováno v:
Journal of Neurochemistry. 70:2327-2335
Exposure of human neuroblastoma cells (IMR-32) to a peptide mimic of the cytoplasmic amphiphilic domain of the common neurotrophin receptor (p75NTR 367–379) resulted in enhanced nerve growth factor (NGF)-mediated inhibition of cell invasion in vitr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59adfdd5507759f8fa2909df675afb56
https://doi.org/10.1046/j.1471-4159.1998.70062327.x
https://doi.org/10.1046/j.1471-4159.1998.70062327.x
Autor:
Philip N. Vrkljan, Kenneth E. Neet, Mark Solc, Gail Lawrance, Igor L. Shamovsky, Richard J. Riopelle, Joan I. Post, Suzanne M. Dostaler, Gregory M. Ross, Sang B. Woo
Publikováno v:
Journal of Neurochemistry. 78:515-523
It has recently been shown that transition metal cations Zn2+ and Cu2+ bind to histidine residues of nerve growth factor (NGF) and other neurotrophins (a family of proteins important for neuronal survival) leading to their inactivation. Experimental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::905db55da3d8786bea8b760b41c6c894
https://doi.org/10.1046/j.1471-4159.2001.00427.x
https://doi.org/10.1046/j.1471-4159.2001.00427.x
Autor:
Igor L. Shamovsky, Mark Solc, Gregory M. Ross, Wei Wang, Rajatavo Maitra, Richard J. Riopelle, Suzanne M. Dostaler, Gail Lawrance
Publikováno v:
Neurotoxicity Research. 2:321-341
Direct effects of Zn2+ on the conformation and biological activity of nerve growth factor (NGF) have previously been described. Zn2+ binds to specific coordination sites within NGF and induces conformational changes within domains that participate in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b886908d709a47accb0daa394944ffd
https://doi.org/10.1007/bf03033341
https://doi.org/10.1007/bf03033341
Autor:
Richard J. Riopelle, Igor L. Shamovsky, Gail Lawrance, Mark Solc, Suzanne M. Dostaler, Gregory M. Ross, Donald F. Weaver
Publikováno v:
European Journal of Neuroscience. 10:890-898
Equilibrium binding of 125I-nerve growth factor (125I-NGF) to cells coexpressing the tyrosine kinase receptor A (TrkA) and common neurotrophin receptor (p75NTR), cells coexpressing both receptors where p75NTR is occupied, and cells expressing only p7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::326b318421b3cf008f123dce86506cfe
https://doi.org/10.1046/j.1460-9568.1998.00094.x
https://doi.org/10.1046/j.1460-9568.1998.00094.x
Publikováno v:
Journal of neurovirology. 14(5)
It is generally accepted that there are not prominent features of neuronal cell death in rabies encephalitis. However, Hemachudha and coworkers recently reported widespread apoptosis in the central nervous system of several human rabies cases (BMC In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d53dbf14550a8647ef6cc2b8b467e69a
https://pubmed.ncbi.nlm.nih.gov/19023689
https://pubmed.ncbi.nlm.nih.gov/19023689
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 310(2)
The neurotrophin nerve growth factor (NGF) binds to two receptor types: the tyrosine kinase receptor TrkA and the common neurotrophin receptor p75(NTR). Although many of the biological effects of NGF (such as neuronal growth and survival) are associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb799ce7916e665090ad470f15be1cd
https://pubmed.ncbi.nlm.nih.gov/15051797
https://pubmed.ncbi.nlm.nih.gov/15051797
Autor:
Sandra L. Jimmo, Donald F. Weaver, Suzanne M. Dostaler, Richard J. Riopelle, Mark Solc, Igor L. Shamovsky, Gail Lawrance, Gregory M. Ross
Publikováno v:
Nature medicine. 3(8)
A role for Zn2+ in a variety of neurological conditions such as stroke, epilepsy and Alzheimer's disease has been postulated. In many instances, susceptible neurons are located in regions rich in Zn2+ where nerve growth factor (NGF) levels rise as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2994b8a87fe2c8c0498fcbc0a93c47e
https://pubmed.ncbi.nlm.nih.gov/9256278
https://pubmed.ncbi.nlm.nih.gov/9256278