Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Gail L. White"'
Autor:
Vanessa J. Marshall, Deirdre Cooper-Blacketer, Bradley T. Hyman, Steven G. Younkin, Mark Andrew Good, Karen K. Hsiao, Paul F. Chapman, Linda H. Younkin, Michael C. Irizarry, Matt Jones, Timothy V. P. Bliss, Gail L. White
Publikováno v:
Nature neuroscience. 2(3)
We investigated synaptic communication and plasticity in hippocampal slices from mice overexpressing mutated 695-amino-acid human amyloid precursor protein (APP695SWE), which show behavioral and histopathological abnormalities simulating Alzheimer's
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c515cfb9cbdc68e9f9d55e6fe756e5bb
https://pubmed.ncbi.nlm.nih.gov/10195221
https://pubmed.ncbi.nlm.nih.gov/10195221
Autor:
Vincenzo Cestari, Liliana Minichiello, Mark Ramsey, Rüdiger Klein, Alistair J. Roylance, Caroline E. Herron, Clelia Rossi-Arnaud, Emmapaola Sturani, David P. Wolfer, Gail L. White, Hans-Peter Lipp, Nerina Gnesutta, Seth G. N. Grant, Paul F. Chapman, Riccardo Brambilla
Publikováno v:
Nature. 390(6657)
Members of the Ras subfamily of small guanine-nucleotide-binding proteins are essential for controlling normal and malignant cell proliferation as well as cell differentiation. The neuronal-specific guanine-nucleotide-exchange factor, Ras-GRF/CDC25Mm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4b200324fdd649d401ff71469c83507
https://pubmed.ncbi.nlm.nih.gov/9384379
https://pubmed.ncbi.nlm.nih.gov/9384379
Publikováno v:
Mutation Research Letters. 142:203-207
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171d7073cb1b83585601aac1f354202a
https://doi.org/10.1016/0165-7992(85)90024-7
https://doi.org/10.1016/0165-7992(85)90024-7
Publikováno v:
Mutation Research/Genetic Toxicology. 171:123-129
The mononitro-substituted isomers of benzo[a]pyrene (B[a]P), 1-, 3- and 6-nitrobenzo[a]pyrene (NB[a]P), are environmental pollutants and are metabolized to mutagens in Salmonella by rat-liver homogenate postmitochondrial supernatant (S9) fractions. I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d609f409cf3cd644392ac8a753ce4b6
https://doi.org/10.1016/0165-1218(86)90044-3
https://doi.org/10.1016/0165-1218(86)90044-3
Publikováno v:
Proceedings of the National Academy of Sciences. 79:5175-5178
The DNA adducts formed during incubation of the hepatocarcinogen N-hydroxy-2-acetylaminofluorene with Salmonella typhimurium tester strain TA1538 were investigated to determine if the covalently bound products were identical to those adducts found in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28bd56b1753cfc3bab282b8d1458001f
https://doi.org/10.1073/pnas.79.17.5175
https://doi.org/10.1073/pnas.79.17.5175
Autor:
Frederick A. Beland, Robert H. Heflich, Carl E. Cerniglia, E. Kim Fifer, Wirt Franklin, Kenneth J. Lambert, Gail L. White
Publikováno v:
Toxicity Assessment. 3:147-159
Dinitropyrenes (DNPs) are highly mutagenic in the Salmonella reversion assay and are tumorigenic in rodents. Bacterial nitroreductases have been implicated in the mutagenic activation of DNPs. In this study, we investigated the metabolism of 1,8-dini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c97cd919db97a38343b54200e23f1f4
https://doi.org/10.1002/tox.2540030206
https://doi.org/10.1002/tox.2540030206
Publikováno v:
Archives of microbiology. 143(2)
The mutagenic activity of ethyl acetate extracts of culture medium from Cunninghamella elegans incubated 72 h with various polycyclic aromatic hydrocarbons (PAHs) was evaluated in the Salmonella typhimurium reversion assay. All of the PAH extracts we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be40e89adb289b0823d3bb7a99d770e
https://pubmed.ncbi.nlm.nih.gov/3907570
https://pubmed.ncbi.nlm.nih.gov/3907570
Publikováno v:
Environmental mutagenesis. 5(4)
Reversions induced by N-hydroxy-2-acetylaminofluorene (N-OH-AAF) were measured in the Salmonella/microsome quantitative plate assay using various concentrations of Salmonella typhimurium strain TA1538. The number of induced revertants increased with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1192d30e8519ccf629813a41993214cd
https://pubmed.ncbi.nlm.nih.gov/6347679
https://pubmed.ncbi.nlm.nih.gov/6347679
Autor:
Dwight W. Miller, Ming W. Chou, Peter P. Fu, Robert H. Heflich, Frederick A. Beland, Gail L. White
Publikováno v:
Mutation research. 143(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d9fdd0e74a69f8835092c1f91fc3415
https://pubmed.ncbi.nlm.nih.gov/3892279
https://pubmed.ncbi.nlm.nih.gov/3892279
Publikováno v:
Mutation research. 144(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1befdc0d618673f668fa4b204b555fed
https://pubmed.ncbi.nlm.nih.gov/3897840
https://pubmed.ncbi.nlm.nih.gov/3897840