Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Gail L. Matters"'
Autor:
Thomas Abraham, Michael Armold, Christopher McGovern, John F. Harms, Matthew C. Darok, Christopher Gigliotti, Bernadette Adair, Jennifer L. Gray, Deborah F. Kelly, James H. Adair, Gail L. Matters
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 1024 (2024)
The poor prognosis for pancreatic ductal adenocarcinoma (PDAC) patients is due in part to the highly fibrotic nature of the tumors that impedes delivery of therapeutics, including nanoparticles (NPs). Our prior studies demonstrated that proglumide, a
Externí odkaz:
https://doaj.org/article/85620d2cf3f04e5fb8a9c21c20eea1f4
Autor:
Gail L. Matters, John F. Harms
Publikováno v:
Biomedicines, Vol 6, Iss 2, p 65 (2018)
It is estimated that early detection of pancreatic ductal adenocarcinoma (PDAC) could increase long-term patient survival by as much as 30% to 40% (Seufferlein, T. et al., Nat. Rev. Gastroenterol. Hepatol. 2016, 13, 74–75). There is an unmet need f
Externí odkaz:
https://doaj.org/article/7b338ea1d89b4cab8e619271fd8d5a8b
Autor:
Samuel S Linton, Thomas Abraham, Jason Liao, Gary A Clawson, Peter J Butler, Todd Fox, Mark Kester, Gail L Matters
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206759 (2018)
Pancreatic ductal adenocarcinoma (PDAC) tumor growth is enhanced by tumor-associated macrophages (TAMs), yet the mechanisms by which tumor cells and TAMs communicate are not fully understood. Here we show that exosomes secreted by PDAC cell lines dif
Externí odkaz:
https://doaj.org/article/495acc41cb8146748e25edd7984ee8a2
Autor:
Gary A Clawson, Gail L Matters, Ping Xin, Christopher McGovern, Eric Wafula, Claude dePamphilis, Morgan Meckley, Joyce Wong, Luke Stewart, Christopher D'Jamoos, Naomi Altman, Yuka Imamura Kawasawa, Zhen Du, Loren Honaas, Thomas Abraham
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184451 (2017)
Here we describe isolation and characterization of macrophage-tumor cell fusions (MTFs) from the blood of pancreatic ductal adenocarcinoma (PDAC) patients. The MTFs were generally aneuploidy, and immunophenotypic characterizations showed that the MTF
Externí odkaz:
https://doaj.org/article/fa7de66a036c4da8bd6e11b0a3d3591c
Autor:
Gary A Clawson, Gail L Matters, Ping Xin, Yuka Imamura-Kawasawa, Zhen Du, Diane M Thiboutot, Klaus F Helm, Rogerio I Neves, Thomas Abraham
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134320 (2015)
BackgroundWhile the morbidity and mortality from cancer are largely attributable to its metastatic dissemination, the integral features of the cascade are not well understood. The widely accepted hypothesis is that the primary tumor microenvironment
Externí odkaz:
https://doaj.org/article/8ca562dcfbbf4e0788b9e3c45deaa2ce
Autor:
Christopher O. McGovern, James H. Adair, Samuel S. Linton, Thomas Abraham, Zachary R. Wilczynski, Gail L. Matters
Publikováno v:
International Journal of Nanomedicine
Thomas Abraham,1 Christopher O McGovern,2 Samuel S Linton,2 Zachary Wilczynski,3 James H Adair,3,4 Gail L Matters2 1Departments of Neural and Behavioral Sciences and the Microscopy Imaging Core Facility, The Pennsylvania State University College of M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e5bdb4292a8def3e2f3599934b7d779
https://www.dovepress.com/aptamer-targeted-calcium-phosphosilicate-nanoparticles-for-effective-i-peer-reviewed-article-IJN
https://www.dovepress.com/aptamer-targeted-calcium-phosphosilicate-nanoparticles-for-effective-i-peer-reviewed-article-IJN
Autor:
Bernadette M. Adair, Cecilia Zemanek, Gail L. Matters, Andrea M. Mastro, Alison B. Shupp, Christopher M. Gigliotti, Christopher O. McGovern, Zi Kui Liu, Karen M. Bussard, Welley Siu Loc, Jenna M. Snyder, Nicholas T. Gigliotti, Zachary R. Wilczynski, James H. Adair, Kacey D Meisel
Publikováno v:
Nanomedicine
Calcium phosphosilicate nanoparticles (CPSNPs) are bioresorbable nanoparticles that can be bioconjugated with targeting molecules and encapsulate active agents -and deliver them to tumor cells without causing damage to adjacent healthy tissue. Data o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bc8a70aaad70cc314c6042f7894fbc2
https://doi.org/10.1016/j.nano.2021.102383
https://doi.org/10.1016/j.nano.2021.102383
Autor:
Walter Varhue, Nathan S. Swami, Mark Kester, Gail L. Matters, Vahid Farmehini, Samuel S. Linton, John H. Moore, Yi-Hsuan Su, Todd E. Fox
Publikováno v:
Analytical chemistry. 91(16)
Diagnostics based on exosomes and other extracellular vesicles (EVs) are emerging as strategies for informing cancer progression and therapies, since the lipid content and macromolecular cargo of EVs can provide key phenotypic and genotypic informati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c9fe3d3d316f33a13ad13cd37d88554
https://pubmed.ncbi.nlm.nih.gov/31333013
https://pubmed.ncbi.nlm.nih.gov/31333013
Autor:
Christopher O. McGovern, Thomas Abraham, Gail L. Matters, James H. Adair, Gary A. Clawson, Wade Edris, Xiaomeng Tang
Publikováno v:
Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XVII.
Prostate cancer (PCA) is the most common cancer and the third most common cause of cancer death in men. Targeted nanoparticles (NPs) that deliver effective doses of chemotherapeutic drugs specifically to PCA could improve chemotherapy efficacy withou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47733a4af1de16a458c8e8fdc59272eb
https://doi.org/10.1117/12.2508833
https://doi.org/10.1117/12.2508833
Autor:
John F. Harms, Gail L. Matters
Publikováno v:
Biomedicines, Vol 6, Iss 2, p 65 (2018)
Biomedicines
Biomedicines
It is estimated that early detection of pancreatic ductal adenocarcinoma (PDAC) could increase long-term patient survival by as much as 30% to 40% (Seufferlein, T. et al., Nat. Rev. Gastroenterol. Hepatol. 2016, 13, 74–75). There is an unmet need f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4173a85cbf583a4a5dc744cc1eb2ef3c
http://www.mdpi.com/2227-9059/6/2/65
http://www.mdpi.com/2227-9059/6/2/65