Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Gail L Sturdevant"'
Autor:
Rebecca M Broeckel, Friederike Feldmann, Kristin L McNally, Abhilash I Chiramel, Gail L Sturdevant, Jacqueline M Leung, Patrick W Hanley, Jamie Lovaglio, Rebecca Rosenke, Dana P Scott, Greg Saturday, Fadila Bouamr, Angela L Rasmussen, Shelly J Robertson, Sonja M Best
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1009678 (2021)
Kyasanur Forest disease virus (KFDV) and the closely related Alkhurma hemorrhagic disease virus (AHFV) are emerging flaviviruses that cause severe viral hemorrhagic fevers in humans. Increasing geographical expansion and case numbers, particularly of
Externí odkaz:
https://doaj.org/article/e75b0f0e8a774ab2b7bf41f32357fe43
Autor:
Gayatri Subramanian, Adam Hage, Friederike Feldmann, Abhilash I. Chiramel, Kristin L. McNally, Gail L. Sturdevant, Paul A. Beare, Sonja M. Best
Publikováno v:
Viruses, Vol 16, Iss 9, p 1377 (2024)
The unprecedented research effort associated with the emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) included several extensive proteomic studies that identified host proteins that interact with individual viral gene produc
Externí odkaz:
https://doaj.org/article/b6f86d9456e7430c99d8646e2ca3fe4f
Autor:
Shelly J. Robertson, Olivia Bedard, Kristin L. McNally, Carl Shaia, Chad S. Clancy, Matthew Lewis, Rebecca M. Broeckel, Abhilash I. Chiramel, Jeffrey G. Shannon, Gail L. Sturdevant, Rebecca Rosenke, Sarah L. Anzick, Elvira Forte, Christoph Preuss, Candice N. Baker, Jeffrey M. Harder, Catherine Brunton, Steven Munger, Daniel P. Bruno, Justin B. Lack, Jacqueline M. Leung, Amirhossein Shamsaddini, Paul Gardina, Daniel E. Sturdevant, Jian Sun, Craig Martens, Steven M. Holland, Nadia A. Rosenthal, Sonja M. Best
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Inflammation in response to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection drives severity of coronavirus disease 2019 (COVID-19) and is influenced by host genetics. To understand mechanisms of inflammation, animal mo
Externí odkaz:
https://doaj.org/article/4707d2cef54a462c9164528ec8d5861f
Publikováno v:
Pathogens, Vol 13, Iss 2, p 167 (2024)
Single-cell RNA sequencing has soared in popularity in recent years. The ability to deeply profile the states of individual cells during the course of disease or infection has helped to expand our knowledge of coordinated responses. However, signific
Externí odkaz:
https://doaj.org/article/5b877b4717a34e428dcc232105ab2f33
Autor:
Shelly J, Robertson, Olivia, Bedard, Kristin L, McNally, Matthew, Lewis, Chad, Clancy, Carl, Shaia, Rebecca M, Broeckel, Abhilash I, Chiramel, Gail L, Sturdevant, Elvira, Forte, Christoph, Preuss, Candice N, Baker, Jeffrey, Harder, Catherine, Brunton, Steven, Munger, Daniel E, Sturdevant, Craig, Martens, Steven M, Holland, Nadia A, Rosenthal, Sonja M, Best
Publikováno v:
bioRxiv
Inflammation in response to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection drives severity of coronavirus disease 2019 (COVID-19), with effective versus dysregulated responses influenced by host genetics. To understand mechani
Autor:
Emily Speranza, Jyothi N Purushotham, Julia R Port, Benjamin Schwarz, Meaghan Flagg, Brandi N Williamson, Friederike Feldmann, Manmeet Singh, Lizzette Pérez-Pérez, Gail L Sturdevant, Lydia M Roberts, Aaron Carmody, Jonathan E Schulz, Neeltje van Doremalen, Atsushi Okumura, Jamie Lovaglio, Patrick W Hanley, Carl Shaia, Ronald N Germain, Sonja M Best, Vincent J Munster, Catharine M Bosio, Emmie de Wit
Publikováno v:
Life science alliance. 5(4)
Advanced age is a key predictor of severe COVID-19. To gain insight into this relationship, we used the rhesus macaque model of SARS-CoV-2 infection. Eight older and eight younger macaques were inoculated with SARS-CoV-2. Animals were evaluated using
Autor:
Shelly J. Robertson, Olivia Bedard, Kristin L. McNally, Carl Shaia, Chad Clancy, Matthew Lewis, Rebecca M. Broeckel, Abhilash I. Chiramel, Jeffrey G. Shannon, Gail L. Sturdevant, Rebecca Rosenke, Sarah L. Anzick, Elvira Forte, Christoph Preuss, Candice N. Baker, Jeffrey Harder, Catherine Brunton, Steven Munger, Daniel P. Bruno, Justin B. Lack, Jacqueline M. Leung, Amirhossein Shamsaddini, Paul Gardina, Daniel E. Sturdevant, Jian Sun, Craig Martens, Steven M. Holland, Nadia A. Rosenthal, Sonja M. Best
Inflammation in response to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection drives severity of coronavirus disease 2019 (COVID-19) and is influenced by host genetics. To understand mechanisms of inflammation, animal models that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7acc6cacad3e94dcb00d2fb0b4b8e651
https://doi.org/10.1101/2021.09.17.460664
https://doi.org/10.1101/2021.09.17.460664
Autor:
Jyothi N. Purushotham, Julia R Port, Manmeet Singh, Lydia M. Roberts, Jonathan E Schulz, Patrick W. Hanley, Catharine M. Bosio, Atsushi Okumura, Benjamin Schwarz, Gail L. Sturdevant, Brandi N. Williamson, Sonja M. Best, Lizzette Pérez-Pérez, Jamie Lovaglio, Friederike Feldmann, Ronald N. Germain, Emily Speranza, Aaron B. Carmody, Carl Shaia, Emmie de Wit, Vincent J. Munster, Meaghan Flagg, Neeltje van Doremalen
Advanced age is a key predictor of severe COVID-19. To gain insight into this relationship, particularly with respect to immune responses, we utilized the rhesus macaque model of SARS-CoV-2 infection. Two cohorts of eight older (16-23 years) and eigh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::726dae533f9e34fc120335482920f1bb
https://doi.org/10.1101/2021.09.08.459430
https://doi.org/10.1101/2021.09.08.459430
Autor:
Rebecca Rosenke, Craig Martens, Cindi L. Schwartz, Forrest Jessop, Shelly J. Robertson, Dylan Gallegos, Catherine Kendall, Sonja M. Best, Arielle Hay, Greg Saturday, Matthew Lewis, Gail L. Sturdevant, Kristin L. McNally, Sanket S. Ponia, Catharine M. Bosio
Dysregulated inflammation dominated by chemokine expression is a key feature of disease following infection with the globally important human pathogens, Zika virus (ZIKV) and dengue virus, but a mechanistic understanding of how pro-inflammatory respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::942ec6fc777b65ea2a20f8cc87d0bee5
https://doi.org/10.1101/2021.01.29.428870
https://doi.org/10.1101/2021.01.29.428870
Autor:
Heinz Feldmann, Atsushi Okumura, Kimberly Meade-White, Brandi N. Williamson, Friederike Feldmann, Brian J. Smith, Sonja M. Best, Lizzette Pérez Pérez, Jamie Lovaglio, Emmie de Wit, Gail L. Sturdevant, Vincent J. Munster, Carl Shaia, Emily Speranza, Craig Martens
Publikováno v:
Science Translational Medicine
Single-cell RNA sequencing of lungs of SARS-CoV-2–infected African green monkeys reveals virus replication and host response dynamics in vivo.
A dynamic response to SARS-CoV-2 While a number of animal models for SARS-CoV-2 have been developed,
A dynamic response to SARS-CoV-2 While a number of animal models for SARS-CoV-2 have been developed,