Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Gail L Griffin"'
Autor:
Tracy L Adair-Kirk, Gail L Griffin, Michelle J Meyer, Diane G Kelley, Jeffrey H Miner, Douglas R Keene, M Peter Marinkovich, J Michael Ruppert, Jouni Uitto, Robert M Senior
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45546 (2012)
Laminin-332 is a heterotrimeric basement membrane component comprised of the α3, ß3, and γ2 laminin chains. Laminin-332 modulates epithelial cell processes, such as adhesion, migration, and differentiation and is prominent in many embryonic and ad
Externí odkaz:
https://doaj.org/article/0d0b7f25a524459b96d7840d807b0f76
Autor:
Gail L. Griffin, Jeffrey J. Atkinson, Daphne E. deMello, Robert M. Senior, Mark A. Watson, Tomoko Betsuyaku, Diane G. Kelley, Tracy L. Adair-Kirk
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 39:400-411
Cigarette smoke (CS) is the main risk factor for chronic obstructive pulmonary disease (COPD). Terminal bronchioles are critical zones in the pathophysiology of COPD, but little is known about the cellular and molecular changes that occur in cells li
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 25:278-284
Terminal airways are affected in many lung diseases and toxic inhalations. To elucidate the changes in terminal airways in these diverse situations it will be helpful to profile and quantify gene expression in terminal bronchiolar epithelium. We used
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 23:742-747
Laminins are trimeric glycoprotein components of basement membranes. Each laminin has three structurally similar chains, designated alpha, beta, and gamma. Five laminin alpha chains are now known. In previous studies using monoclonal antibody 4C7, la
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 276:L131-L136
Human pulmonary surfactant protein D (SP-D) is a collagenous C-type lectin with high binding specificity to α-d-glucosyl residues. It is composed of four regions: a short NH2-terminal noncollagen sequence, a collagenous domain, a short linking domai
Autor:
H D Gresham, Robert M. Senior, Albert E. Chung, Jyh-Cheng Hsieh, Li-Jin Dong, Gail L. Griffin, Irene L. Graham
Publikováno v:
Journal of Biological Chemistry. 271:30587-30594
Extracellular matrix proteins activate neutrophils to up-regulate many physiologic functions that are necessary at sites of tissue injury. To elucidate the ligand-receptor interactions that mediate these functions, we examined neutrophil activation b
Autor:
Richard A. Pierce, M. A. Moxley, Gail L. Griffin, Robert M. Senior, W. J. Longmore, M. S. Mudd
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 14:239-247
Although the composition of the subepithelial basement membrane of the alveolar septum has been studied in detail, there is relatively little information about which cells produce it. We examined intact rat lung and isolated rat alveolar type II cell
Autor:
Howard G. Welgus, G. Murphy, Robert M. Senior, Ulrike I. Sires, Robert P. Mecham, Gail L. Griffin, Thomas J. Broekelmann, A.E. Chung
Publikováno v:
Journal of Biological Chemistry. 268:2069-2074
Entactin is the basement membrane protein which bridges laminin and type IV collagen. Entactin is known to be degraded by serine proteinases, but its susceptibility to matrix metalloproteinases has not been determined. We have studied the capacity of
Autor:
Gail L. Griffin, Tracy L. Adair-Kirk, Robert M. Senior, J. M. Ruppert, Adrian Shifren, Jouni Uitto, Diane G. Kelley
Publikováno v:
D64. CELL-CELL/CELL-MATRIX INTERACTIONS.
Autor:
Robert J. Fallon, Robert M. Senior, Anna M. August, S P Adams, Gail L. Griffin, Gregg Joslin, David H. Perlmutter
Publikováno v:
Journal of Clinical Investigation. 90:1150-1154
The serpin-enzyme complex (SEC) receptor mediates catabolism of alpha 1-antitrypsin (alpha 1-AT)-elastase complexes and increases in synthesis of alpha 1-AT in cell culture. The SEC receptor recognizes a pentapeptide domain on alpha 1-AT-elastase com