Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Gail K. Provuncher"'
Hypoxia due to cardiac arrest induces a time-dependent increase in serum amyloid β levels in humans.
Autor:
Henrik Zetterberg, Erik Mörtberg, Linan Song, Lei Chang, Gail K Provuncher, Purvish P Patel, Evan Ferrell, David R Fournier, Cheuk W Kan, Todd G Campbell, Ray Meyer, Andrew J Rivnak, Brian A Pink, Kaitlin A Minnehan, Tomasz Piech, David M Rissin, David C Duffy, Sten Rubertsson, David H Wilson, Kaj Blennow
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28263 (2011)
Amyloid β (Aβ) peptides are proteolytic products from amyloid precursor protein (APP) and are thought to play a role in Alzheimer disease (AD) pathogenesis. While much is known about molecular mechanisms underlying cerebral Aβ accumulation in fami
Externí odkaz:
https://doaj.org/article/bd279e68e5df447f8caafa35e86ed2e2
Autor:
Robert P. Thiel, Gail K. Provuncher, Lei Chang, Lori J. Sokoll, Dan W. Chan, Linan Song, Alan W. Partin, Carol D. Cheli, Evan P. Ferrell, David C. Duffy, David Fournier, Herbert Lepor, David H. Wilson, Purvish P. Patel, David Hanlon
Publikováno v:
Clinical Chemistry. 57:1712-1721
BACKGROUNDMeasurement of prostate-specific antigen (PSA) in prostate cancer patients following radical prostatectomy (RP) has been hindered by the limit of quantification of available assays. Because radical prostatectomy removes the tissue responsib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42bb31613d8057471afdba187bc01014
https://doi.org/10.1373/clinchem.2011.169540
https://doi.org/10.1373/clinchem.2011.169540
Autor:
David H. Wilson, Purvish P. Patel, Linan Song, Andrew J. Rivnak, Brian A. Pink, Mary A. Till, Lei Chang, Cheuk W. Kan, David C. Duffy, Gail K. Provuncher, David Hanlon, Kaitlin A. Minnehan, David Fournier, William A. Faubion, Evan P. Ferrell, Todd G. Campbell
Publikováno v:
Journal of Immunological Methods. 372:177-186
The quantitative measurement of inflammatory cytokines in blood has been limited by insufficient sensitivity of conventional immunoassays. This limitation has prevented the widespread clinical monitoring of cytokine concentrations in chronic inflamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e50154c2f5380203bc377483f10542b7
https://doi.org/10.1016/j.jim.2011.07.015
https://doi.org/10.1016/j.jim.2011.07.015
Autor:
Cheuk W. Kan, Brian A. Pink, David H. Wilson, Purvish P. Patel, David C. Duffy, David M. Rissin, Linan Song, David Fournier, Evan P. Ferrell, Andrew J. Rivnak, Tomasz Piech, Gail K. Provuncher, Stuart C. Howes, Lei Chang, Kaitlin A. Minnehan, Todd G. Campbell
Publikováno v:
Analytical Chemistry. 83:2279-2285
We report a method for combining the detection of single molecules (digital) and an ensemble of molecules (analog) that is capable of detecting enzyme label from 10(-19) M to 10(-13) M, for use in high sensitivity enzyme-linked immunosorbent assays (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3779dfc2a308af6b419c2748130c308c
https://doi.org/10.1021/ac103161b
https://doi.org/10.1021/ac103161b
Autor:
Jeffrey Randall, Cheuk W. Kan, Andrew J. Rivnak, Tomasz Piech, Purvish P. Patel, David C. Duffy, David R. Walt, David Fournier, Gail K. Provuncher, Stuart C. Howes, Lei Chang, David M. Rissin, Linan Song, Todd G. Campbell, Evan P. Ferrell
Publikováno v:
Nature biotechnology
The ability to detect single protein molecules in blood could accelerate the discovery and use of more sensitive diagnostic biomarkers. To detect low-abundance proteins in blood, we captured them on microscopic beads decorated with specific antibodie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae6867354f00d0c7695315b37a4dcef6
https://doi.org/10.1038/nbt.1641
https://doi.org/10.1038/nbt.1641
Autor:
Andreas Jeromin, Jeff Randall, Denise Wilson, Stefania Mondello, Firas Kobeissy, Gail K. Provuncher, David Hanlon, Andras Buki, Pál Barzó
Publikováno v:
Scientific Reports
The role of amyloid-β (Aβ) neuropathology and its significant changes in biofluids after traumatic brain injury (TBI) is still debated. We used ultrasensitive digital ELISA approach to assess amyloid-β1-42 (Aβ42) concentrations and time-course in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ca7034e7a4444a74269b6ca90e48c0
https://pubmed.ncbi.nlm.nih.gov/25300247
https://pubmed.ncbi.nlm.nih.gov/25300247
Autor:
Erik Mörtberg, Kaj Blennow, Sten Rubertsson, David Fournier, Jeffrey Randall, Henrik Zetterberg, David H. Wilson, Gail K. Provuncher, David C. Duffy
Publikováno v:
Resuscitation. 84(3)
To conduct a pilot study to evaluate the prognostic potential of serum tau protein measurements to predict neurological outcome 6 months following resuscitation from cardiac arrest.In this retrospective observational study, we employed a new ultra se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ada57dac0bde508cedb3d90c47247f4
https://pubmed.ncbi.nlm.nih.gov/22885094
https://pubmed.ncbi.nlm.nih.gov/22885094
Autor:
Kaj Blennow, Brian A. Pink, Erik Mörtberg, David Fournier, Sten Rubertsson, Gail K. Provuncher, Lei Chang, Ray E. Meyer, Andrew J. Rivnak, David H. Wilson, Purvish P. Patel, Evan P. Ferrell, David M. Rissin, Henrik Zetterberg, Linan Song, Todd G. Campbell, Kaitlin A. Minnehan, Cheuk W. Kan, David C. Duffy, Tomasz Piech
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28263 (2011)
PLoS ONE
PLoS ONE
Amyloid β (Aβ) peptides are proteolytic products from amyloid precursor protein (APP) and are thought to play a role in Alzheimer disease (AD) pathogenesis. While much is known about molecular mechanisms underlying cerebral Aβ accumulation in fami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd1b36190d6adda85de62526025506c4
https://doi.org/10.1371/journal.pone.0028263
https://doi.org/10.1371/journal.pone.0028263
Autor:
David M. Rissin, Tomasz Piech, Jeff Randall, David M. Wilson, David R. Walt, Cheuk W. Kan, Andrew J. Rivnak, Stuart C. Howes, Linan Song, Gail K. Provuncher, Purvish P. Patel, David C. Duffy, David Fournier, Evan P. Ferrell, Todd G. Campbell
Publikováno v:
Clinical Cancer Research. 16:B14-B14
Purpose: Develop a method for measuring prostate specific antigen (PSA) in the serum of patients who have undergone radical prostatectomy (RP). The method is based on Single Molecule Array (SiMoATM) technology in which individual molecules of analyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cdedc88b0ec52ae45aecce1793e24af
https://doi.org/10.1158/diag-10-b14
https://doi.org/10.1158/diag-10-b14