Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Gail H. Gurtner"'
Publikováno v:
Journal of Applied Toxicology. 18:321-329
This study investigated the post-treatment effect of isoproterenol (ISO) on pulmonary parameters in rabbits whole-body-exposed to a lethal dose of the toxic gas phosgene. Phosgene is widely used in industry as a chemical intermediate for the producti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83069cd639ed523011e57cfdb7867b57
https://doi.org/10.1002/(sici)1099-1263(1998090)18:5<321::aid-jat516>3.0.co
https://doi.org/10.1002/(sici)1099-1263(1998090)18:5<321::aid-jat516>3.0.co
Publikováno v:
Experimental Lung Research. 23:317-332
Pretreatment with aminophylline has been shown to protect against various types of acute lung injury. Mechanisms responsible for protection are multifactorial but are thought to involve upregulation of cAMP. While previous studies focused on pretreat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13104303372764d179c9c777aaea3d2d
https://doi.org/10.3109/01902149709039229
https://doi.org/10.3109/01902149709039229
Publikováno v:
Journal of Applied Physiology. 80:149-157
Phosgene, a toxic gas widely used as an industrial chemical intermediate, is known to cause life-threatening latent noncardiogenic pulmonary edema. Mechanisms related to its toxicity appear to involve lipoxygenase mediators of arachidonic acid (AA) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::568e5d37bcdc5492c5cfd2615a4ba08e
https://doi.org/10.1152/jappl.1996.80.1.149
https://doi.org/10.1152/jappl.1996.80.1.149
Publikováno v:
Journal of Applied Physiology. 72:416-422
Exposing rabbits for 1 h to 100% O2 at 4 atm barometric pressure markedly increases the concentration of thromboxane B2 in alveolar lavage fluid [1,809 +/- 92 vs. 99 +/- 24 (SE) pg/ml, P less than 0.001], pulmonary arterial pressure (110 +/- 17 vs. 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f1002cecccf184ddbf3521005a696f9
https://doi.org/10.1152/jappl.1992.72.2.416
https://doi.org/10.1152/jappl.1992.72.2.416
Publikováno v:
Journal of Applied Physiology. 68:1252-1259
Two major lines of defense exist against oxidant lung injury: tissue antioxidants and antioxidant enzymes. We studied pretreatment with the antioxidants, vitamin E and butylated hydroxyanisole (BHA), and the antioxidant enzymes, superoxide dismutase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1635ed433be5b935d11c167fbca209e3
https://doi.org/10.1152/jappl.1990.68.3.1252
https://doi.org/10.1152/jappl.1990.68.3.1252
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781489918154
We have previously found that 5,6-EET (epoxyeicosatrienoic acid)(50 nM) significantly dilates the vascular bed(42%) of the isolated, constantly perfused rabbit lung, which has been constricted with U46619(5-8 pM). We studied the role of EDRF-NO and p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edbea08c313b7c57da4dfa6c87f129d1
https://doi.org/10.1007/978-1-4899-1813-0_85
https://doi.org/10.1007/978-1-4899-1813-0_85
Publikováno v:
American journal of respiratory and critical care medicine. 151(3 Pt 1)
We examined the effects of treatment with N-acetylcysteine (NAC) on pulmonary edema formation in isolated perfused rabbit lungs following in vivo phosgene exposure. This study focused on posttreatment intratracheal administration of NAC after exposur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d80104fd9e4725a35e879bb93d17d5
https://pubmed.ncbi.nlm.nih.gov/7881668
https://pubmed.ncbi.nlm.nih.gov/7881668
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 74(6)
We find spontaneous light emission from isolated Krebs-Henseleit-perfused rabbit lungs when the light-emitting super-oxide trap lucigenin is added to the perfusate. Lucigenin light emission appears to be specific for superoxide anion, because light e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d68cdf43988a51233b3c889a46ed8a3
https://pubmed.ncbi.nlm.nih.gov/8396109
https://pubmed.ncbi.nlm.nih.gov/8396109
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 74(3)
We studied the effects of three chemically distinct protein kinase C activators on pulmonary vascular tone in the buffer-perfused isolated rabbit lung. The three activators, 12-deoxyphorbol 13-isobutyrate (12,13-phorbol), mezerein, and 1-oleoyl-2-ace
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71ddb41d1330764670ac1260642b344
https://pubmed.ncbi.nlm.nih.gov/8482672
https://pubmed.ncbi.nlm.nih.gov/8482672
Autor:
Gail H. Gurtner
Publikováno v:
Vascular Endothelium ISBN: 9781461360353
We find spontaneous light emission from isolated Krebs Henseleit perfused rabbit lungs when the light emitting superoxide trap lucigenin is added to the perfusate. Lucigenin light emission appears to be specific for superoxide anion since light emiss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbc7ce6062bf41cc79a815672f837aca
https://doi.org/10.1007/978-1-4615-2437-3_30
https://doi.org/10.1007/978-1-4615-2437-3_30