Zobrazeno 1 - 10
of 437
pro vyhledávání: '"Gail Eckhardt"'
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/747d98bb50a740bbb288548f0e610dfd
Autor:
John J. Tentler, Julie Lang, Anna Capasso, Deog Joong Kim, Ely Benaim, Young B. Lee, Andrew Eisen, Stacey M. Bagby, Sarah J. Hartman, Betelehem W. Yacob, Brian Gittleman, Todd M. Pitts, Roberta Pelanda, S. Gail Eckhardt, Jennifer R. Diamond
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype with limited systemic treatment options. RX-5902 is a novel anti-cancer agent that inhibits phosphorylated-p68 and thus attenuates nuclear β-catenin sign
Externí odkaz:
https://doaj.org/article/1dcda43bbcb945d6ae883320daa5d648
Autor:
Woojung Shin, Alexander Wu, Soyoun Min, Yong Cheol Shin, R. Y. Declan Fleming, S. Gail Eckhardt, Hyun Jung Kim
Publikováno v:
iScience, Vol 23, Iss 8, Pp 101372- (2020)
Summary: In a conventional culture of three-dimensional human intestinal organoids, extracellular matrix hydrogel has been used to provide a physical space for the growth and morphogenesis of organoids in the presence of exogenous morphogens such as
Externí odkaz:
https://doaj.org/article/d796b1ac37cb424ab58e2473ad1322ef
Autor:
Peter J. Klauck, Stacey M. Bagby, Anna Capasso, Erica L. Bradshaw-Pierce, Heather M. Selby, Anna Spreafico, John J. Tentler, Aik Choon Tan, Jihye Kim, John J. Arcaroli, Alicia Purkey, Wells A. Messersmith, Keisuke Kuida, S. Gail Eckhardt, Todd M. Pitts
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background Polo-like kinase 1 (Plk1) is a serine/threonine kinase that is a key regulator of multiple stages of mitotic progression. Plk1 is upregulated in many tumor types including colorectal cancer (CRC) and portends a poor prognosis. TAK
Externí odkaz:
https://doaj.org/article/d4dd779ae0964c9eb1a995ae2b3952c9
Autor:
Xu Hua, Yongsheng Li, Sairahul R. Pentaparthi, Daniel J. McGrail, Raymond Zou, Li Guo, Aditya Shrawat, Kara M. Cirillo, Qing Li, Akshay Bhat, Min Xu, Dan Qi, Ashok Singh, Francis McGrath, Steven Andrews, Kyaw Lwin Aung, Jishnu Das, Yunyun Zhou, Alessia Lodi, Gordon B. Mills, S. Gail Eckhardt, Marc L. Mendillo, Stefano Tiziani, Erxi Wu, Jason H. Huang, Nidhi Sahni, S. Stephen Yi
Publikováno v:
Cancer Research. 83:59-73
Somatic mutations are a major source of cancer development, and many driver mutations have been identified in protein coding regions. However, the function of mutations located in miRNA and their target binding sites throughout the human genome remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88cb29e8ae8421d1dd36a93b92b336ae
https://doi.org/10.1158/0008-5472.can-20-0371
https://doi.org/10.1158/0008-5472.can-20-0371
Autor:
Milad Soleimani, Alexander Somma, Tamer Kaoud, Ria Goyal, Jorge Bustamante, Dennis C. Wylie, Nisha Holay, Agnieszka Looney, Uma Giri, Todd Triplett, Kevin Dalby, Jeanne Kowalski, S. Gail Eckhardt, Carla Van Den Berg
Publikováno v:
Molecular Cancer Therapeutics. 21:1547-1560
The heterogeneity and aggressiveness of triple-negative breast cancer (TNBC) contribute to its early recurrence and metastasis. Despite substantial research to identify effective therapeutic targets, TNBC remains elusive in terms of improving patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab09dfa0d80024292cbba0fa5a68d31f
https://doi.org/10.1158/1535-7163.mct-21-1044
https://doi.org/10.1158/1535-7163.mct-21-1044
Autor:
S. Gail Eckhardt, Patrick W. Vincent, Shawn M. O'Connell, Robyn Fabrey, Esha Gangolli, Todd M. Pitts, Peter J. Klauck, S. Lindsey Davis, Kelli M. Robertson, Kelsey L. Brunkow, Heather M. Selby, Aik-Choon Tan, John J. Tentler, Lindsey N. Micel
Suppl Figure 3. Immunoblot of Effector Proteins and Markers of Apoptosis in Melanoma Cell Lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::029a0ba35ac9fcdd6c94102286927194
https://doi.org/10.1158/1535-7163.22502620.v1
https://doi.org/10.1158/1535-7163.22502620.v1
Autor:
Douglas K. Graham, Deborah DeRyckere, H. Shelton Earp, Stephen V. Frye, Xiaodong Wang, S. Gail Eckhardt, Tal Burstyn-Cohen, Rotem Kami, William A. Robinson, Stacey M. Bagby, Jacqueline Carrico, John J. Tentler, Katherine A. Minson, Lenka Sinik
Supplemental Figure 2 shows impact of UNC2025 on colony forming potential.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13be068ca67762efe397a83c5d6586b8
https://doi.org/10.1158/1535-7163.22508884.v1
https://doi.org/10.1158/1535-7163.22508884.v1
Autor:
S. Gail Eckhardt, Patrick W. Vincent, Shawn M. O'Connell, Robyn Fabrey, Esha Gangolli, Todd M. Pitts, Peter J. Klauck, S. Lindsey Davis, Kelli M. Robertson, Kelsey L. Brunkow, Heather M. Selby, Aik-Choon Tan, John J. Tentler, Lindsey N. Micel
Suppl Figure 2. Immunoblot Analysis of Effector Proteins in Melanoma Cell Lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::684326f5e97806bb407ca57792581e9b
https://doi.org/10.1158/1535-7163.22502626
https://doi.org/10.1158/1535-7163.22502626
Autor:
Douglas K. Graham, Deborah DeRyckere, H. Shelton Earp, Stephen V. Frye, Xiaodong Wang, S. Gail Eckhardt, Tal Burstyn-Cohen, Rotem Kami, William A. Robinson, Stacey M. Bagby, Jacqueline Carrico, John J. Tentler, Katherine A. Minson, Lenka Sinik
Supplemental Figure 4 shows TAM-family kinase expression in melanoma cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e925147742d72fe1c33fb2b661b6de5
https://doi.org/10.1158/1535-7163.22508878.v1
https://doi.org/10.1158/1535-7163.22508878.v1