Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Gail E. McElhaney-Feser"'
Autor:
Ursula Mocek, Ted L. Underiner, Sheldon E. Broedel, Gail E. McElhaney-Feser, Robert E. Raulli, Jodi A. Laakso, Paul Actor, Brian J. Hotovec, Ronald L. Cihlar
Publikováno v:
Journal of Natural Products. 66:1041-1046
A systematic screen for new natural products that displayed antifungal activity by inhibition of fungal fatty acid synthase (FAS) led to the discovery of two new fungal metabolites, designated CT2108A (1) and CT2108B (2). The metabolites were produce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed488c143650a930af65d96c4a156141
https://doi.org/10.1021/np030046g
https://doi.org/10.1021/np030046g
Publikováno v:
Infection and Immunity. 65:829-832
Disruption of both alleles of the Candida albicans FAS2 gene abolishes the ability of the organism to establish infection in a murine model of systemic candidiasis. Within 72 h all mice inoculated with 10(6) CFU of the parental C. albicans strain had
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eec14d07019e13662a3676139626de26
https://doi.org/10.1128/iai.65.2.829-832.1997
https://doi.org/10.1128/iai.65.2.829-832.1997
Autor:
Henk J. Busscher, Henny C. van der Mei, Jesse B. Cohen, Bastiaan P. Krom, Gail E. McElhaney-Feser, Ronald L. Cihlar
Publikováno v:
Candida albicans ISBN: 9781588297600
Development of Candida spp. biofilms on medical devices such as catheters and voice prosthesis has been recognized as an increasing clinical problem. Simple device removal is often impossible, while in addition, resulting candidal infections are diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3504b319d287a00b26741c5b2d385439
https://doi.org/10.1007/978-1-60327-151-6_7
https://doi.org/10.1007/978-1-60327-151-6_7
The candidacidal activity of nitric oxide (NO) as delivered by a class of compounds termed diazeniumdiolates has been investigated. Diazeniumdiolates are stable agents capable of releasing NO in a biologically usable form at a predicted rate, and thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fad2b7d26a40dafa98d0383c2676ea76
https://europepmc.org/articles/PMC105830/
https://europepmc.org/articles/PMC105830/
Autor:
Michael F. Cole, Gail E. McElhaney-Feser, Ronald L. Cihlar, Sheldon E. Broedel, Xiao-jiong Zhao, William H. Bowen
Publikováno v:
Microbiology (Reading, England). 142
The virulence of Candida albicans strains deficient in fatty acid synthase activity by virtue of disruption/deletion of the FAS2 gene was examined in a rat model of oropharyngeal candidiasis. The FAS2 alleles of C. albicans CAI4 (delta ura3::imm434/d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04ac1e74aa624d8de4afc44781ac2723
https://pubmed.ncbi.nlm.nih.gov/8828218
https://pubmed.ncbi.nlm.nih.gov/8828218