A study protocol for a multi-country cluster randomized controlled trial of the impact of a multi-component One Health strategy to eliminate Opisthorchis viverrini and soil transmitted helminths in the Lower Mekong Basin

Autor: Mary Lorraine Mationg, Archie C. A. Clements, Gail M. Williams, Matthew Kelly, Donald E. Stewart, Catherine A. Gordon, Kinley Wangdi, Sirikachorn Tangkawattana, Apiporn T. Suwannatrai, Vanathom Savathdy, Visal Khieu, Sangduan Wannachart, Suji Yoo O’Connor, Simon Forsyth, Sean Gannon, Peter Odermatt, Donald P. McManus, Somphou Sayasone, Virak Khieu, Banchob Sripa, Darren J. Gray

Publikováno v: Trials, Vol 25, Iss 1, Pp 1-12 (2024)

Abstract Background Opisthorchis viverrini (OV) and soil-transmitted helminths (STH) are two of the most common helminths contributing to the Neglected Tropical Disease (NTDs) burden in the Lower Mekong Basin. Although mass drug administration is the

Externí odkaz: https://doaj.org/article/3d45a826c81e40a29dc36f9bdec6db56

First bovine vaccine to prevent human schistosomiasis - a cluster randomised Phase 3 clinical trial

Autor: Allen G. Ross, Donald A. Harn, Delia Chy, Marianette Inobaya, Jerric R. Guevarra, Lisa Shollenberger, Yuesheng Li, Donald P. McManus, Darren J. Gray, Gail M. Williams

Publikováno v: International Journal of Infectious Diseases, Vol 129, Iss , Pp 110-117 (2023)

Objective: Schistosomiasis is a neglected tropical parasitic disease caused by blood flukes of the genus Schistosoma. Schistosoma japonicum is zoonotic in China, the Philippines, and Indonesia, with bovines acting as major reservoirs of human infecti

Externí odkaz: https://doaj.org/article/6804d26ae1da4facba67f5bc20d36fcb

High prevalence of soil-transmitted helminth infections in Myanmar schoolchildren

Autor: Eindra Aung, Kay Thwe Han, Catherine A. Gordon, Nyein Nyein Hlaing, Moe Moe Aye, Myo Win Htun, Khin Thet Wai, Su Mon Myat, Thida Lay Thwe, Aung Tun, Kinley Wangdi, Yuesheng Li, Gail M. Williams, Archie C. A. Clements, Susana Vaz Nery, Donald P. McManus, Darren J. Gray

Publikováno v: Infectious Diseases of Poverty, Vol 11, Iss 1, Pp 1-12 (2022)

Abstract Background Achieving the elimination of soil-transmitted helminth (STH) infections requires a sufficient understanding of the current epidemiological status of STH endemicity. We aimed to examine the status of STH in Myanmar – a country wi

Externí odkaz: https://doaj.org/article/30a5db3b64c24410a075c8e9fbde77a4

Genetic association study of childhood aggression across raters, instruments, and age

Autor: Hill F. Ip, Camiel M. van der Laan, Eva M. L. Krapohl, Isabell Brikell, Cristina Sánchez-Mora, Ilja M. Nolte, Beate St Pourcain, Koen Bolhuis, Teemu Palviainen, Hadi Zafarmand, Lucía Colodro-Conde, Scott Gordon, Tetyana Zayats, Fazil Aliev, Chang Jiang, Carol A. Wang, Gretchen Saunders, Ville Karhunen, Anke R. Hammerschlag, Daniel E. Adkins, Richard Border, Roseann E. Peterson, Joseph A. Prinz, Elisabeth Thiering, Ilkka Seppälä, Natàlia Vilor-Tejedor, Tarunveer S. Ahluwalia, Felix R. Day, Jouke-Jan Hottenga, Andrea G. Allegrini, Kaili Rimfeld, Qi Chen, Yi Lu, Joanna Martin, María Soler Artigas, Paula Rovira, Rosa Bosch, Gemma Español, Josep Antoni Ramos Quiroga, Alexander Neumann, Judith Ensink, Katrina Grasby, José J. Morosoli, Xiaoran Tong, Shelby Marrington, Christel Middeldorp, James G. Scott, Anna Vinkhuyzen, Andrey A. Shabalin, Robin Corley, Luke M. Evans, Karen Sugden, Silvia Alemany, Lærke Sass, Rebecca Vinding, Kate Ruth, Jess Tyrrell, Gareth E. Davies, Erik A. Ehli, Fiona A. Hagenbeek, Eveline De Zeeuw, Toos C.E.M. Van Beijsterveldt, Henrik Larsson, Harold Snieder, Frank C. Verhulst, Najaf Amin, Alyce M. Whipp, Tellervo Korhonen, Eero Vuoksimaa, Richard J. Rose, André G. Uitterlinden, Andrew C. Heath, Pamela Madden, Jan Haavik, Jennifer R. Harris, Øyvind Helgeland, Stefan Johansson, Gun Peggy S. Knudsen, Pal Rasmus Njolstad, Qing Lu, Alina Rodriguez, Anjali K. Henders, Abdullah Mamun, Jackob M. Najman, Sandy Brown, Christian Hopfer, Kenneth Krauter, Chandra Reynolds, Andrew Smolen, Michael Stallings, Sally Wadsworth, Tamara L. Wall, Judy L. Silberg, Allison Miller, Liisa Keltikangas-Järvinen, Christian Hakulinen, Laura Pulkki-Råback, Alexandra Havdahl, Per Magnus, Olli T. Raitakari, John R. B. Perry, Sabrina Llop, Maria-Jose Lopez-Espinosa, Klaus Bønnelykke, Hans Bisgaard, Jordi Sunyer, Terho Lehtimäki, Louise Arseneault, Marie Standl, Joachim Heinrich, Joseph Boden, John Pearson, L. John Horwood, Martin Kennedy, Richie Poulton, Lindon J. Eaves, Hermine H. Maes, John Hewitt, William E. Copeland, Elizabeth J. Costello, Gail M. Williams, Naomi Wray, Marjo-Riitta Järvelin, Matt McGue, William Iacono, Avshalom Caspi, Terrie E. Moffitt, Andrew Whitehouse, Craig E. Pennell, Kelly L. Klump, S. Alexandra Burt, Danielle M. Dick, Ted Reichborn-Kjennerud, Nicholas G. Martin, Sarah E. Medland, Tanja Vrijkotte, Jaakko Kaprio, Henning Tiemeier, George Davey Smith, Catharina A. Hartman, Albertine J. Oldehinkel, Miquel Casas, Marta Ribasés, Paul Lichtenstein, Sebastian Lundström, Robert Plomin, Meike Bartels, Michel G. Nivard, Dorret I. Boomsma

Publikováno v: Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)

Abstract Childhood aggressive behavior (AGG) has a substantial heritability of around 50%. Here we present a genome-wide association meta-analysis (GWAMA) of childhood AGG, in which all phenotype measures across childhood ages from multiple assessors

Externí odkaz: https://doaj.org/article/882fa84e3ace4249a3c5e7bb582ea021

'The Magic Glasses Philippines': a cluster randomised controlled trial of a health education package for the prevention of intestinal worm infections in schoolchildren

Autor: Mary Lorraine S Mationg, Gail M Williams, Veronica L Tallo, Remigio M Olveda, Eindra Aung, Portia Alday, Mark Donald Reñosa, Chona Mae Daga, Jhoys Landicho, Maria Paz Demonteverde, Eunice Diane Santos, Thea Andrea Bravo, Franziska Angly Bieri, Andrew Bedford, Yuesheng Li, Archie C A Clements, Peter Steinmann, Kate Halton, Donald E Stewart, Donald P McManus, Darren J Gray

Publikováno v: The Lancet Regional Health. Western Pacific, Vol 18, Iss , Pp 100312- (2022)

Summary: Background: Soil-transmitted helminths (STH) cause substantial disease and disability globally. Health education has proven complementary to school-based drug administration programs for STH control. We determined the generalizability of the

Externí odkaz: https://doaj.org/article/cc7681dc1574421f941820b813dcb482