Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Gail, Sharpless"'
Autor:
Kathryn A. Carson, Garry R. Cutting, Joseph M. Collaco, Peter J. Mogayzel, Pamela L. Zeitlin, Melis A. Aksit, Vanessa L. Richardson, Beth L. Laube, Christopher M. Evans, Gail Sharpless
Publikováno v:
Pediatric Research. 91:612-620
Background This research characterized mucociliary clearance (MCC) in young children with cystic fibrosis (CF). Methods Fourteen children (5-7 years old) with CF underwent: two baseline MCC measurements (Visits 1 and 2); one MCC measurement approxima
Autor:
Gail Sharpless, Christopher M. Evans, Peter J. Mogayzel, Kathryn A. Carson, Vanessa L. Richardson, Pamela L. Zeitlin, Beth L. Laube
Publikováno v:
Pediatr Pulmonol
Objectives (a) To quantify changes in mucociliary clearance (MCC) over time in children with cystic fibrosis (CF) and the relationship between MCC and rate of infection with Pseudomonas aeruginosa (PA); (b) to determine the impact of MCC on the evolu
Publikováno v:
J Aerosol Med Pulm Drug Deliv
Background: Little is known of the repeatability and reliability of mucociliary clearance (MCC) in former tobacco smokers who have both chronic obstructive pulmonary disease (COPD) and chronic bronchitis (CB). Less is known of the effect of roflumila
Autor:
Beth L, Laube, Kathryn A, Carson, Christopher M, Evans, Melis A, Aksit, Joseph M, Collaco, Vanessa L, Richardson, Gail, Sharpless, Pamela L, Zeitlin, Garry R, Cutting, Peter J, Mogayzel
Publikováno v:
Pediatric research. 91(3)
This research characterized mucociliary clearance (MCC) in young children with cystic fibrosis (CF).Fourteen children (5-7 years old) with CF underwent: two baseline MCC measurements (Visits 1 and 2); one MCC measurement approximately 1 year later (V
Autor:
Gail Sharpless, Scott H. Donaldson, Jihong Wu, Peter J. Mogayzel, Beth L. Laube, Kirby L. Zeman, William D. Bennett
Publikováno v:
Journal of Aerosol Medicine and Pulmonary Drug Delivery. 31:204-211
Background: Using planar gamma scintigraphy of inhaled radioaerosols, we have developed new analytical methods for assessing homogeneity of aerosol deposition and time-dependent particle clearance on a pixel-by-pixel basis, and applied them to a ther
Deposition of Dry Powder Generated by Solovent in Sophia Anatomical Infant Nose-Throat (SAINT) Model
Publikováno v:
Aerosol Science and Technology. 46:514-520
Purpose: To quantify deposition of 99mtechnetium-labeled powder in the Sophia Anatomical Infant Nose-Throat (SAINT) model of a 9-month old. Methods: Powder was generated by the Solovent (BD Technologies), an active dry powder inhaler with spacer, dur
Autor:
Keith Sedberry, Gail Sharpless, Vincent Harrand, Darin Knaus, Simeon J. Zinreich, Mark J. Papania, Ami R. Vikani, Beth L. Laube, James J. Barry
Publikováno v:
Journal of aerosol medicine and pulmonary drug delivery. 28(5)
To our knowledge, quantification of intranasal deposition of aerosol generated by Accuspray(™) (AS) in children has never been published. We hypothesized that deposition would vary significantly with age and with placement of the device within, or
Publikováno v:
The Journal of pediatrics. 164(4)
Objective To determine if mucus removal is impaired in children with cystic fibrosis (CF) who have been recently infected with Pseudomonas aeruginosa . Study design We compared mucociliary clearance (MCC), cough clearance (CC), lung morphology, and f
Autor:
Jihong Wu, Kristina Thomas, William D. Bennett, Joseph M. Pilewski, Peter J. Mogayzel, Gail Sharpless, Scott H. Donaldson, Timothy E. Corcoran, Beth L. Laube, Kirby L. Zeman
Publikováno v:
Journal of aerosol medicine and pulmonary drug delivery. 26(3)
A standardized protocol for measuring mucociliary (MCC) and cough clearance (CC) was developed and tested at the University of North Carolina at Chapel Hill, NC (UNC), Johns Hopkins University (JHU), and the University of Pittsburgh (Pitt).A total of
Autor:
Gail Sharpless, Charles Shermer, Kenneth G. Powell, Omer Nasir, Beth L. Laube, Vincent J. Sullivan
Publikováno v:
Pharmaceutical research. 27(8)
To quantify distribution of albuterol aerosol generated by a pneumatic nebulizer within the nose and lungs of a model of a 9-month-old child (SAINT) and aerosol loss to the environment, during simulated breathing at increasing tidal volumes (TVs).(99