Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Gaik W, Tew"'
Autor:
Margaret Neighbors, Qingling Li, Sha (Joe) Zhu, Jia Liu, Weng Ruh Wong, Guiquan Jia, Wendy Sandoval, Gaik W. Tew
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 6, Pp 100375- (2023)
Idiopathic pulmonary fibrosis (IPF) is a progressive disease with significant mortality. Prognostic biomarkers to identify rapid progressors are urgently needed to improve patient management. Since the lysophosphatidic acid (LPA) pathway has been imp
Externí odkaz:
https://doaj.org/article/6495128bfe724bb1ae4121a00cd0aaff
Autor:
Qingling Li, Weng Wong, Andrew Birnberg, Arindam Chakrabarti, Xiaoying Yang, David F. Choy, Julie Olsson, Erik Verschueren, Margaret Neighbors, Wendy Sandoval, Carrie M. Rosenberger, Michele A. Grimbaldeston, Gaik W. Tew
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background Chronic obstructive pulmonary disease (COPD) exacerbations are heterogenous and profoundly impact the disease trajectory. Bioactive lipid lysophosphatidic acid (LPA) has been implicated in airway inflammation but the significance
Externí odkaz:
https://doaj.org/article/fb00e03d0f8641e9bbfca8c9c870db5b
Autor:
Elise M. A. Slob, Alen Faiz, Jos vanNijnatten, Susanne J. H. Vijverberg, Cristina Longo, Merve Kutlu, Fook Tim Chew, Yang Yie Sio, Esther Herrera‐Luis, Antonio Espuela‐Ortiz, Javier Perez‐Garcia, Maria Pino‐Yanes, Esteban G. Burchard, Uroš Potočnik, Mario Gorenjak, Colin Palmer, Cyrielle Maroteau, Steve Turner, Katia Verhamme, Leila Karimi, Somnath Mukhopadhyay, Wim Timens, Pieter S. Hiemstra, Mariëlle W. Pijnenburg, Margaret Neighbors, Michele A. Grimbaldeston, Gaik W. Tew, Corry A. Brandsma, Vojko Berce, Hananeh Aliee, Fabian Theis, Don D. Sin, Xuan Li, Maarten van denBerge, Anke H. Maitland‐van der Zee, Gerard H. Koppelman
Publikováno v:
Clinical and Translational Allergy, Vol 12, Iss 8, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/aad33376d38744ce9d92723e7fc44c1d
Autor:
Arindam Chakrabarti, Jordan S. Mar, David F. Choy, Yi Cao, Nisha Rathore, Xiaoying Yang, Gaik W. Tew, Olga Li, Prescott G. Woodruff, Christopher E. Brightling, Michele Grimbaldeston, Stephanie A. Christenson, Mona Bafadhel, Carrie M. Rosenberger
Publikováno v:
ERJ Open Research, Vol 7, Iss 3 (2021)
Introduction COPD exacerbations are heterogeneous and can be triggered by bacterial, viral, or noninfectious insults. Exacerbations are also heterogeneous in neutrophilic or eosinophilic inflammatory responses. A noninvasive peripheral biomarker of C
Externí odkaz:
https://doaj.org/article/692862264ef245069cba5c9438c1380c
Autor:
Benedikt Ditz, Jeunard G. Boekhoudt, Hananeh Aliee, Fabian J. Theis, Martijn Nawijn, Corry-Anke Brandsma, Pieter S. Hiemstra, Wim Timens, Gaik W. Tew, Michele A. Grimbaldeston, Margaret Neighbors, Victor Guryev, Maarten van den Berge, Alen Faiz
Publikováno v:
ERJ Open Research, Vol 7, Iss 2 (2021)
Externí odkaz:
https://doaj.org/article/5bebb9ea5ee9414d8bed32f6738661c0
Autor:
Kasia Owczarczyk, Matthew D. Cascino, Cecile Holweg, Gaik W. Tew, Ward Ortmann, Timothy Behrens, Thomas Schindler, Carol A. Langford, E. William St. Clair, Peter A. Merkel, Robert Spiera, Philip Seo, Cees G.M. Kallenberg, Ulrich Specks, Noha Lim, John Stone, Paul Brunetta, Marco Prunotto, the RAVE-ITN Research Group
Publikováno v:
JCI Insight, Vol 5, Iss 18 (2020)
BACKGROUND Baseline expression of FCRL5, a marker of naive and memory B cells, was shown to predict response to rituximab (RTX) in rheumatoid arthritis. This study investigated baseline expression of FCRL5 as a potential biomarker of clinical respons
Externí odkaz:
https://doaj.org/article/b7bd1818f0e642e5849a9f696ba49b07
Autor:
Arindam Chakrabarti, Xiaoying Yang, Qingling Li, Margaret Neighbors, Erik Verschueren, Julie Olsson, Andrew Birnberg, Carrie M. Rosenberger, Weng Wong, Michele A. Grimbaldeston, Wendy Sandoval, David F. Choy, Gaik W. Tew
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-12 (2021)
Background Chronic obstructive pulmonary disease (COPD) exacerbations are heterogenous and profoundly impact the disease trajectory. Bioactive lipid lysophosphatidic acid (LPA) has been implicated in airway inflammation but the significance of LPA in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b31f0427f86658f99d652f2d6ed429b2
https://doaj.org/article/fb00e03d0f8641e9bbfca8c9c870db5b
https://doaj.org/article/fb00e03d0f8641e9bbfca8c9c870db5b
Autor:
Michele A. Grimbaldeston, Arindam Chakrabarti, Yi Cao, Nisha Rathore, Stephanie A. Christenson, Prescott G. Woodruff, Xiaoying Yang, Jordan S. Mar, Christopher E. Brightling, David F. Choy, Olga Li, Mona Bafadhel, Carrie M. Rosenberger, Gaik W. Tew
Publikováno v:
ERJ Open Research. :00836-2020
IntroductionCOPD exacerbations are heterogeneous and can be triggered by bacterial, viral, or non-infectious insults. Exacerbations are also heterogeneous in neutrophilic or eosinophilic inflammatory responses. A non-invasive peripheral biomarker of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7124477736b61ed80a20d5085657647
https://doi.org/10.1183/23120541.00836-2020
https://doi.org/10.1183/23120541.00836-2020
Autor:
K Malmström, A. Faiz, Maria Stella de Biase, Corry-Anke Brandsma, Michele A. Grimbaldeston, Gaik W. Tew, Basil Khuder, Cheng-Jian Xu, G. H. Koppelman, Pieter S. Hiemstra, Cancan Qi, Sile Hu, Roland F. Schwarz, Hananeh Aliee, Paul A. Reyfman, Florian Massip, Robert C. Rintoul, N. H. Hacken, Fabian J. Theis, Ian M. Adcock, Xiaoyu Zhang, Nazanin Zounemat Kermani, Bruce A.J. Ponder, Mika J. Mäkelä, Martijn C. Nawijn, Elin T G Kersten, Jos van Nijnatten, Judith M. Vonk, Roel Vermeulen, Kai Sun, Yike Guo, W. Timens, Margaret Neighbors, Maarten van den Berge
Publikováno v:
Allergy, 77(2), 690-694. Wiley-Blackwell
Allergy 77, 690-694 (2022)
Allergy
Allergy 77, 690-694 (2022)
Allergy
The recent outbreak of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), has led to a worldwide pandemic. One week after initial symptoms develop, a subset of patients progresses to se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbfc08900ba6bff3883ef5eb83e3323a
https://research.rug.nl/en/publications/833b995e-0f95-4c0e-867b-41a33d5370e4
https://research.rug.nl/en/publications/833b995e-0f95-4c0e-867b-41a33d5370e4
Autor:
Pieter S. Hiemstra, Gaik W. Tew, Hananeh Aliee, Benedikt Ditz, Maarten van den Berge, Jeunard Boekhoudt, Michele A. Grimbaldeston, Fabian J. Theis, Alen Faiz, Corry-Anke Brandsma, Martijn C. Nawijn, Victor Guryev, Wim Timens, Margaret Neighbors
Publikováno v:
ERJ Open Res. 7:00104-2021 (2021)
ERJ Open Research, 7(2):00104-2021. European Respiratory Society
ERJ Open Research, Vol 7, Iss 2 (2021)
ERJ Open Research, 7(2):00104-2021. European Respiratory Society
ERJ Open Research, Vol 7, Iss 2 (2021)
More DEGs are detected by RNA-Seq than microarrays in COPD lung biopsies and are associated with immunological pathways. Performing bulk tissue cell-type deconvolution in microarray lung samples, using the SVR method, reflects RNA-Seq results. https:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4311e7e95c645c3fb1efe0bb18d8bf95
https://doi.org/10.1183/23120541.00104-2021
https://doi.org/10.1183/23120541.00104-2021