Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Gaia Pedriali"'
Autor:
Esther Densu Agyapong, Gaia Pedriali, Daniela Ramaccini, Esmaa Bouhamida, Elena Tremoli, Carlotta Giorgi, Paolo Pinton, Giampaolo Morciano
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Acute myocardial infarction (AMI) is a serious condition that occurs when part of the heart is subjected to ischemia episodes, following partial or complete occlusion of the epicardial coronary arteries. The resulting damage to heart muscle
Externí odkaz:
https://doaj.org/article/3718a08fe980456aaf1f78d3374639c5
Autor:
Gaia Pedriali, Daniela Ramaccini, Esmaa Bouhamida, Mariusz R. Wieckowski, Carlotta Giorgi, Elena Tremoli, Paolo Pinton
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Cardiovascular disease is the most common cause of death worldwide and in particular, ischemic heart disease holds the most considerable position. Even if it has been deeply studied, myocardial ischemia-reperfusion injury (IRI) is still a side-effect
Externí odkaz:
https://doaj.org/article/d180767971644109924df195ded2fab2
Autor:
Esmaa Bouhamida, Giampaolo Morciano, Gaia Pedriali, Daniela Ramaccini, Elena Tremoli, Carlotta Giorgi, Paolo Pinton, Simone Patergnani
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 11105 (2023)
Calcific aortic valve stenosis (CAVS) is among the most common causes of cardiovascular mortality in an aging population worldwide. The pathomechanisms of CAVS are such a complex and multifactorial process that researchers are still making progress t
Externí odkaz:
https://doaj.org/article/2a3e2885c6df4605b7b16e11dd1be452
Autor:
Gaia Pedriali, Daniela Ramaccini, Esmaa Bouhamida, Alessio Branchini, Giulia Turrin, Elisabetta Tonet, Antonella Scala, Simone Patergnani, Mirko Pinotti, Claudio Trapella, Carlotta Giorgi, Elena Tremoli, Gianluca Campo, Giampaolo Morciano, Paolo Pinton
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6191 (2023)
Permeability transition pore (PTP) molecular composition and activity modulation have been a matter of research for several years, especially due to their importance in ischemia reperfusion injury (IRI). Notably, c subunit of ATP synthase (Csub) has
Externí odkaz:
https://doaj.org/article/6615912d10184b4dbb87c6e0f8db38c6
Autor:
Giampaolo Morciano, Caterina Boncompagni, Daniela Ramaccini, Gaia Pedriali, Esmaa Bouhamida, Elena Tremoli, Carlotta Giorgi, Paolo Pinton
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3414 (2023)
The most common alterations affecting mitochondria, and associated with cardiac pathological conditions, implicate a long list of defects. They include impairments of the mitochondrial electron transport chain activity, which is a crucial element for
Externí odkaz:
https://doaj.org/article/f4c12e5fa3a2432db91d95674014b65a
Autor:
Giampaolo Morciano, Gaia Pedriali, Massimo Bonora, Rita Pavasini, Elisa Mikus, Simone Calvi, Matteo Bovolenta, Magdalena Lebiedzinska-Arciszewska, Mirko Pinotti, Alberto Albertini, Mariusz R. Wieckowski, Carlotta Giorgi, Roberto Ferrari, Lorenzo Galluzzi, Gianluca Campo, Paolo Pinton
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108983- (2021)
Summary: Preclinical models of ischemia/reperfusion injury (RI) demonstrate the deleterious effects of permeability transition pore complex (PTPC) opening in the first minutes upon revascularization of the occluded vessel. The ATP synthase c subunit
Externí odkaz:
https://doaj.org/article/827b58fa4eb044499de5d9de3ee09408
Autor:
Daniela Ramaccini, Gaia Pedriali, Mariasole Perrone, Esmaa Bouhamida, Lorenzo Modesti, Mariusz R. Wieckowski, Carlotta Giorgi, Paolo Pinton, Giampaolo Morciano
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 726 (2022)
The heart is one of the most fascinating organs in living beings. It beats up to 100,000 times a day throughout the lifespan, without resting. The heart undergoes profound anatomical, biochemical, and functional changes during life, from hypoxemic fe
Externí odkaz:
https://doaj.org/article/ed72184897a8417bb68311c867c26191
Autor:
Gaia Pedriali, Giampaolo Morciano, Simone Patergnani, Paolo Cimaglia, Cristina Morelli, Elisa Mikus, Roberto Ferrari, Vincenzo Gasbarro, Carlotta Giorgi, Mariusz R. Wieckowski, Paolo Pinton
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 14, p 4899 (2020)
Calcific aortic stenosis is a disorder that impacts the physiology of heart valves. Fibrocalcific events progress in conjunction with thickening of the valve leaflets. Over the years, these events promote stenosis and obstruction of blood flow. Known
Externí odkaz:
https://doaj.org/article/3300c481b1e446078f7f8da418defeef
Autor:
Massimo Bonora, Simone Patergnani, Daniela Ramaccini, Giampaolo Morciano, Gaia Pedriali, Asrat Endrias Kahsay, Esmaa Bouhamida, Carlotta Giorgi, Mariusz R. Wieckowski, Paolo Pinton
Publikováno v:
Biomolecules, Vol 10, Iss 7, p 998 (2020)
Mitochondrial permeability transition (MPT) is the sudden loss in the permeability of the inner mitochondrial membrane (IMM) to low-molecular-weight solutes. Due to osmotic forces, MPT is paralleled by a massive influx of water into the mitochondrial
Externí odkaz:
https://doaj.org/article/982f269e7ca6460c899bea75b73bc4e4
Autor:
Gaia Pedriali, Alessandro Rimessi, Luigi Sbano, Carlotta Giorgi, Mariusz R. Wieckowski, Maurizio Previati, Paolo Pinton
Publikováno v:
Frontiers in Oncology, Vol 7 (2017)
Inter-organelle membrane contact sites are emerging as major sites for the regulation of intracellular Ca2+ concentration and distribution. Here, extracellular stimuli operate on a wide array of channels, pumps, and ion exchangers to redistribute int
Externí odkaz:
https://doaj.org/article/57095460c9884ef4afa3ad7253bdeda1