Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Gaia Giuntini"'
Autor:
Alessandro Falsini, Gaia Giuntini, Mattia Mori, Francesca Ghirga, Deborah Quaglio, Antonino Cucinotta, Federica Coppola, Irene Filippi, Antonella Naldini, Bruno Botta, Fabio Carraro
Publikováno v:
Pharmaceuticals, Vol 17, Iss 2, p 227 (2024)
Melanoma is the principal cause of death in skin cancer due to its ability to invade and cause metastasis. Hypoxia, which characterises the tumour microenvironment (TME), plays an important role in melanoma development, as cancer cells can adapt and
Externí odkaz:
https://doaj.org/article/3cbc55a18b1a4bdab49b40f3076dabf2
Autor:
Marta Venturella, Alessandro Falsini, Federica Coppola, Gaia Giuntini, Fabio Carraro, Davide Zocco, Antonio Chiesi, Antonella Naldini
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6122 (2023)
Cutaneous melanoma is a highly aggressive skin cancer, with poor prognosis. The tumor microenvironment is characterized by areas of hypoxia. Carbonic anhydrase IX (CA-IX) is a marker of tumor hypoxia and its expression is regulated by hypoxia-inducib
Externí odkaz:
https://doaj.org/article/1062f65fb62e4eac800082269eb0fda0
Autor:
Sara Monaci, Federica Coppola, Daniela Rossi, Gaia Giuntini, Irene Filippi, Giuseppe Marotta, Silvano Sozzani, Fabio Carraro, Antonella Naldini
Publikováno v:
Cells, Vol 11, Iss 10, p 1695 (2022)
Hypoxia is a component of both physiological and pathological conditions, including inflammation, solid tumors, and lymphoid tissues, where O2 demand is not balanced by O2 supply. During their lifespan, dendritic cells (DCs) are exposed to different
Externí odkaz:
https://doaj.org/article/0e14d1c8ebc843c6a3381b6c64a73dc8
Autor:
Sara Monaci, Carlo Aldinucci, Daniela Rossi, Gaia Giuntini, Irene Filippi, Cristina Ulivieri, Giuseppe Marotta, Silvano Sozzani, Fabio Carraro, Antonella Naldini
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
During their lifespan, dendritic cells (DCs) are exposed to different pO2 levels that affect their differentiation and functions. Autophagy is one of the adaptive responses to hypoxia with important implications for cell survival. While the autophagi
Externí odkaz:
https://doaj.org/article/7d45cba4252840c4b67aa2b97628167e
Autor:
Sara Monaci, Federica Coppola, Gaia Giuntini, Rossella Roncoroni, Francesco Acquati, Silvano Sozzani, Fabio Carraro, Antonella Naldini
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 14, p 7564 (2021)
Hypoxia is a key component of the tumor microenvironment (TME) and promotes not only tumor growth and metastasis, but also negatively affects infiltrating immune cells by impairing host immunity. Dendritic cells (DCs) are the most potent antigen-pres
Externí odkaz:
https://doaj.org/article/3e9865688dfa4e03b49854f6d0e21946
Autor:
Camilla Evangelisti, Francesca Paganelli, Gaia Giuntini, Elisabetta Mattioli, Alessandra Cappellini, Giulia Ramazzotti, Irene Faenza, Maria Cristina Maltarello, Alberto M. Martelli, Katia Scotlandi, Francesca Chiarini, Giovanna Lattanzi
Publikováno v:
Cells, Vol 9, Iss 3, p 774 (2020)
A type lamins are fundamental components of the nuclear lamina. Changes in lamin A expression correlate with malignant transformation in several cancers. However, the role of lamin A has not been explored in osteosarcoma (OS). Here, we wanted to inve
Externí odkaz:
https://doaj.org/article/9cfa258b67404b31b16e33f93be44379
Autor:
Gaia Giuntini, Federica Coppola, Alessandro Falsini, Irene Filippi, Sara Monaci, Antonella Naldini, Fabio Carraro
Publikováno v:
Cancers; Volume 14; Issue 19; Pages: 4776
Background: Malignant melanoma is the leading cause of death among skin cancer patients due to its tendency to metastasize. Alterations at the molecular level are often evident, which is why melanoma biology has garnered increasing interest. The hedg
Publikováno v:
Cancers
Volume 12
Issue 10
Cancers, Vol 12, Iss 3018, p 3018 (2020)
Volume 12
Issue 10
Cancers, Vol 12, Iss 3018, p 3018 (2020)
Background: Intratumoral hypoxia contributes to cancer progression and poor prognosis. Carbonic anhydrases IX (CAIX) and XII (CAXII) play pivotal roles in tumor cell adaptation and survival, as aberrant Hedgehog (Hh) pathway does. In malignant melano
Autor:
Antonella Naldini, Daniela Rossi, Irene Filippi, Sara Monaci, Fabio Carraro, Silvano Sozzani, Cristina Ulivieri, Giuseppe Marotta, Gaia Giuntini, Carlo Aldinucci
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology
During their lifespan, dendritic cells (DCs) are exposed to different pO2 levels that affect their differentiation and functions. Autophagy is one of the adaptive responses to hypoxia with important implications for cell survival. While the autophagi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c9cc25ee6fc37b4a734e91ea13fff7
http://hdl.handle.net/11573/1475223
http://hdl.handle.net/11573/1475223
Autor:
Francesca Chiarini, Elisabetta Mattioli, Irene Faenza, Gaia Giuntini, Camilla Evangelisti, Alberto M. Martelli, Alessandra Cappellini, Francesca Paganelli, Maria Cristina Maltarello, Giovanna Lattanzi, Katia Scotlandi, Giulia Ramazzotti
Publikováno v:
Cells
Volume 9
Issue 3
Cells, Vol 9, Iss 3, p 774 (2020)
Volume 9
Issue 3
Cells, Vol 9, Iss 3, p 774 (2020)
A type lamins are fundamental components of the nuclear lamina. Changes in lamin A expression correlate with malignant transformation in several cancers. However, the role of lamin A has not been explored in osteosarcoma (OS). Here, we wanted to inve