Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Gaia Cermenati"'
Autor:
Alessandra Ferrari, Raffaella Longo, Erika Fiorino, Rui Silva, Nico Mitro, Gaia Cermenati, Federica Gilardi, Béatrice Desvergne, Annapaola Andolfo, Cinzia Magagnotti, Donatella Caruso, Emma De Fabiani, Scott W. Hiebert, Maurizio Crestani
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Histone deacetylases, such as HDAC3, have been shown to alter cellular metabolism in various tissues. Here the authors show that HDAC3 regulates WAT metabolism by activating a futile cycle of fatty acid synthesis and oxidation, which supports WAT bro
Externí odkaz:
https://doaj.org/article/e79e6f94830242d2a35e5f6ab7dac919
Autor:
Gaia Cermenati, Federico Abbiati, Solei Cermenati, Elisabetta Brioschi, Alessandro Volonterio, Guido Cavaletti, Enrique Saez, Emma De Fabiani, Maurizio Crestani, Luis M. Garcia-Segura, Roberto C. Melcangi, Donatella Caruso, Nico Mitro
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 2, Pp 300-310 (2012)
Diabetic peripheral neuropathy (DPN) is characterized by myelin abnormalities; however, the molecular mechanisms underlying such deficits remain obscure. To uncover the effects of diabetes on myelin alterations, we have analyzed myelin composition. I
Externí odkaz:
https://doaj.org/article/537aaa785a8d4d66a8124a6e26b33788
Autor:
Donatella Caruso, Silvia Giatti, Roberto Cosimo Melcangi, Nico Mitro, Matteo Audano, Marzia Pesaresi, Gaia Cermenati, Roberto Spezzano, Silvia Pedretti
Publikováno v:
Journal of Neurochemistry. 142:420-428
Neuroactive steroid levels are altered in several experimental models of peripheral neuropathy, and on this basis, they have been proposed as protective agents. For the first time, the levels of these molecules were here assessed in sterol regulatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8c49559de947d8efd6e7cc4b28007ed
https://doi.org/10.1111/jnc.14063
https://doi.org/10.1111/jnc.14063
Autor:
Silvia Giatti, Marzia Pesaresi, Matteo Audano, Roberto Cosimo Melcangi, Gaia Cermenati, Roberto Spezzano, Nico Mitro, Donatella Caruso
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 168:60-70
Due to the emerging association of diabetes with several psychiatric and neurodegenerative events, the evaluation of the effects of this pathology on the brain function has now a high priority in biomedical research. In particular, the effects of dia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f37a94441c2887f68590b315e5b57bf
https://doi.org/10.1016/j.jsbmb.2017.02.002
https://doi.org/10.1016/j.jsbmb.2017.02.002
Autor:
Donatella Caruso, Erika Fiorino, Maurizio Crestani, E. De Fabiani, Raffaella Longo, Nico Mitro, S. Barilla, Alessandra Ferrari, Uliano Guerrini, Marco Giudici, Gaia Cermenati, Antonello Mai
Publikováno v:
International Journal of Obesity. 41:289-298
In the last decade, a strict link between epigenetics and metabolism has been demonstrated. Histone deacetylases (HDACs) have emerged as key epigenetic regulators involved in metabolic homeostasis in normal and pathologic conditions. Here we investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40433e250c6d9d3df3a818d81f5a3213
https://doi.org/10.1038/ijo.2016.191
https://doi.org/10.1038/ijo.2016.191
Autor:
Maurizio Crestani, Nico Mitro, Donatella Caruso, Matteo Audano, Gaia Cermenati, Roberto Cosimo Melcangi, Emma De Fabiani
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1851:51-60
Lipids in the nervous system accomplish a great number of key functions, from synaptogenesis to impulse conduction, and more. Most of the lipids of the nervous system are localized in myelin sheaths. It has long been known that myelin structure and b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8815b8e02cb44d2f6b47f2ea775b5d19
https://doi.org/10.1016/j.bbalip.2014.08.011
https://doi.org/10.1016/j.bbalip.2014.08.011
Autor:
Nico Mitro, Elisabetta Brioschi, Enrique Saez, Tiziana Bonaldi, Gaia Cermenati, Giuseppe R. Diaferia, Serena Ghisletti, Giuseppe Danilo Norata, Alberico L. Catapano, Alessandro Cuomo, Emma De Fabiani, Donatella Caruso, Andrea Baragetti, Matteo Audano, Liliana Grigore, Marina Mora, Fabrizia Bonacina, Maurizio Crestani, Franco Salerno, Silvia Pedretti, Katia Garlaschelli
Publikováno v:
EMBO reports. 19(4)
Mitochondria are the energy-generating hubs of the cell. In spite of considerable advances, our understanding of the factors that regulate the molecular circuits that govern mitochondrial function remains incomplete. Using a genome-wide functional sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d8e15adf95ad39439129f621e1fdc8c
https://pubmed.ncbi.nlm.nih.gov/29507079
https://pubmed.ncbi.nlm.nih.gov/29507079
Autor:
Scott W. Hiebert, Emma De Fabiani, Cinzia Magagnotti, Erika Fiorino, Donatella Caruso, Béatrice Desvergne, Annapaola Andolfo, Maurizio Crestani, Rui Silva, Gaia Cermenati, Nico Mitro, Federica Gilardi, Raffaella Longo, Alessandra Ferrari
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Nature Communications
Nature Communications, vol. 8, no. 1, pp. 93
Nature Communications
Nature Communications, vol. 8, no. 1, pp. 93
White adipose tissue (WAT) can undergo a phenotypic switch, known as browning, in response to environmental stimuli such as cold. Post-translational modifications of histones have been shown to regulate cellular energy metabolism, but their role in w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c512383fec48820206bfc3269b78fc0b
https://doi.org/10.1038/s41467-017-00182-7
https://doi.org/10.1038/s41467-017-00182-7
Autor:
Donatella Caruso, Emma De Fabiani, Nico Mitro, Luis M. Garcia-Segura, Elisabetta Brioschi, Federico Abbiati, Iñigo Azcoitia, Matteo Audano, Silvia Giatti, Roberto Cosimo Melcangi, Maurizio Crestani, Gaia Cermenati
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 143:115-121
Diabetic peripheral neuropathy causes a decrease in the levels of dihydroprogesterone and 5α-androstane-3α,17β-diol (3α-diol) in the peripheral nerves. These two neuroactive steroids exert protective effects, by mechanisms that still remain elusi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96768c04ff2013fda512d7fea3ae794a
https://doi.org/10.1016/j.jsbmb.2014.02.015
https://doi.org/10.1016/j.jsbmb.2014.02.015
Autor:
C. Godio, E. Gers, Alice Gualerzi, Elena Donetti, Nico Mitro, Donatella Caruso, Gaia Cermenati, Alessandra Ferrari, Enrique Saez, Dante Rotili, Antonello Mai, Uliano Guerrini, Andrea Galmozzi, Emma De Fabiani, Federica Gilardi, Sergio Valente, Maurizio Crestani
Publikováno v:
Diabetes
Chromatin modifications are sensitive to environmental and nutritional stimuli. Abnormalities in epigenetic regulation are associated with metabolic disorders such as obesity and diabetes that are often linked with defects in oxidative metabolism. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c04afbc909846f1e10489704ce2833d1
https://doi.org/10.2337/db12-0548
https://doi.org/10.2337/db12-0548