Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Gagliardi, Alessia"'
Autor:
Ceri, Stefano, Bernasconi, Anna, Gagliardi, Alessia, Martinenghi, Davide, Bellomarini, Luigi, Magnanimi, Davide
Publikováno v:
In Companion of the 2024 International Conference on Management of Data (SIGMOD/PODS '24). Association for Computing Machinery, New York, NY, USA, 373-385
Graph databases are emerging as the leading data management technology for storing large knowledge graphs; significant efforts are ongoing to produce new standards (such as the Graph Query Language, GQL), as well as enrich them with properties, types
Externí odkaz:
http://arxiv.org/abs/2307.07354
Autor:
Gagliardi, Alessia
Embryonic stem (ES) cells are maintained in an undifferentiated state by a gene regulatory network centred on the triumvirate of transcription factors Nanog, Oct4 and Sox2. Genome-wide chromatin immunoprecipitation studies indicate that in many cases
Externí odkaz:
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.699950
Akademický článek
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Graph databases are emerging as the leading data management technology for storing large knowledge graphs; significant efforts are ongoing to produce new standards (such as the Graph Query Language, GQL), as well as enrich them with properties, types
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff9f722e827b437df6eb90cceafbb041
http://arxiv.org/abs/2307.07354
http://arxiv.org/abs/2307.07354
Akademický článek
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Autor:
Chittaranjan, Suganthi, Song, Jungeun, Chan, Susanna Y., Lee, Stephen Dongsoo, Ahmad, Shiekh Tanveer, Brothers, William, Corbett, Richard D., Gagliardi, Alessia, Lum, Amy, Moradian, Annie, Pleasance, Stephen, Coope, Robin, Gregory Cairncross, J, Yip, Stephen, Laks, Emma, Aparicio, Samuel A.J.R., Chan, Jennifer A., Hughes, Christopher S., Morin, Gregg B., LeBlanc, Veronique G., Marra, Marco A.
Background CIC is a transcriptional repressor inactivated by loss-of-function mutations in several cancer types, including gliomas, lung cancers, and gastric adenocarcinomas. CIC alterations and/or loss of CIC activity have been associated with poore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=sharebioRxiv::cf0acd5335a962f14100e1114b25a6b2
Autor:
Festuccia, Nicola, Halbritter, Florian, Corsinotti, Andrea, Gagliardi, Alessia, Colby, Douglas, Tomlinson, Simon R, Chambers, Ian
Publikováno v:
Festuccia, N, Halbritter, F, Corsinotti, A, Gagliardi, A, Colby, D, Tomlinson, S R & Chambers, I 2018, ' Esrrb extinction triggers dismantling of naïve pluripotency and marks commitment to differentiation ', EMBO Journal, vol. 37, no. 21, e95476 . https://doi.org/10.15252/embj.201695476
The EMBO Journal
The EMBO Journal
Self‐renewal of embryonic stem cells (ESCs) cultured in LIF/fetal calf serum (FCS) is incomplete with some cells initiating differentiation. While this is reflected in heterogeneous expression of naive pluripotency transcription factors (TFs), the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6741db177aedcbf2001454a01fd40109
https://hdl.handle.net/20.500.11820/cbba74aa-ea6c-4528-9d4a-0a461aaf1539
https://hdl.handle.net/20.500.11820/cbba74aa-ea6c-4528-9d4a-0a461aaf1539
Autor:
Mullin, Nicholas, Gagliardi, Alessia, Khoa, Le Tran Phuc, Colby, Douglas, Hall-Ponsele, Elisa, Lowe, Arthur J., Chambers, Ian
Publikováno v:
Journal of Molecular Biology
Mullin, N, Gagliardi, A, Khoa, L T P, Colby, D, Hall-Ponsele, E, Lowe, A J & Chambers, I 2017, ' Distinct Contributions of Tryptophan Residues within the Dimerization Domain to Nanog Function ', Journal of Molecular Biology . https://doi.org/10.1016/j.jmb.2016.12.001
Mullin, N, Gagliardi, A, Khoa, L T P, Colby, D, Hall-Ponsele, E, Lowe, A J & Chambers, I 2017, ' Distinct Contributions of Tryptophan Residues within the Dimerization Domain to Nanog Function ', Journal of Molecular Biology . https://doi.org/10.1016/j.jmb.2016.12.001
The level of the transcription factor Nanog directly determines the efficiency of mouse embryonic stem cell self-renewal. Nanog protein exists as a dimer with the dimerization domain composed of a simple repeat region in which every fifth residue is
Akademický článek
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Autor:
Navarro Gil, Pablo, Festuccia, Nicola, Colby, Douglas, Gagliardi, Alessia, Mullin, Nicholas, Zhang, Wensheng, Karwacki-Neisius, Violetta, Osorno, Rodrigo, Kelly, David, Robertson, Morag, Chambers, Ian
Publikováno v:
EMBO Journal
EMBO Journal, EMBO Press, 2012, 31 (24), pp.4547-4562. ⟨10.1038/emboj.2012.321⟩
EMBO Journal, EMBO Press, 2012, 31 (24), pp.4547-4562. ⟨10.1038/emboj.2012.321⟩
International audience; NANOG, OCT4 and SOX2 form the core network of transcription factors supporting embryonic stem (ES) cell self-renewal. While OCT4 and SOX2 expression is relatively uniform, ES cells fluctuate between states of high NANOG expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::22def12105370a267f787b5dc932dd25
https://hal-pasteur.archives-ouvertes.fr/pasteur-02025074
https://hal-pasteur.archives-ouvertes.fr/pasteur-02025074