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Effects of the Known Pathogenic Mutations on the Aggregation Pathway of the Amyloidogenic Peptide of Apolipoprotein A-I

Publikováno v: Journal of Molecular Biology 407 (2011): 465–476. doi:10.1016/j.jmb.2011.01.044
info:cnr-pdr/source/autori:Raimondi S, Guglielmi F, Giorgetti S, Di Gaetano S, Arciello A, Monti DM,Relini A, Nichino D, Doglia SM, Natalello A, Pucci P, Mangione P, Obici L,Merlini G, Stoppini M, Robustelli P, Tartaglia GG, Vendruscolo M, Dobson CM,Piccoli R, Bellotti V/titolo:Effects of the known pathogenic mutations on theaggregation pathway of the amyloidogenic peptide of apolipoprotein A-I/doi:10.1016%2Fj.jmb.2011.01.044/rivista:Journal of Molecular Biology/anno:2011/pagina_da:465/pagina_a:476/intervallo_pagine:465–476/volume:407

The 93-residue N-terminal fragment of apolipoprotein A-I (ApoA-I) is the major constituent of fibrils isolated from patients affected by the amyloidosis caused by ApoA-I mutations. We have prepared eight polypeptides corresponding to all the currentl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c00a8bd9658106980c4a1a373b86af3
https://doi.org/10.1016/j.jmb.2011.01.044

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Akademický článek

High-Resolution Conformational Analysis of RGDechi-Derived Peptides Based on a Combination of NMR Spectroscopy and MD Simulations.

Autor: Acconcia C; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania-Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy., Paladino A; Institute of Biostructures and Bioimaging, CNR, Via Castellino 101, 80131 Naples, Italy., Valle MD; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania-Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy., Farina B; Institute of Biostructures and Bioimaging, CNR, Via Castellino 101, 80131 Naples, Italy.; Advanced Accelerator Applications, A Novartis Company, Via Ribes, 510010 Colleretto Giacosa, Italy., Del Gatto A; Institute of Biostructures and Bioimaging, CNR, Via Castellino 101, 80131 Naples, Italy.; Interdepartmental Center of Bioactive Peptide, University of Naples Federico II, Via Mezzocannone 16, 80134 Naples, Italy., Gaetano SD; Institute of Biostructures and Bioimaging, CNR, Via Castellino 101, 80131 Naples, Italy.; Interdepartmental Center of Bioactive Peptide, University of Naples Federico II, Via Mezzocannone 16, 80134 Naples, Italy., Capasso D; Interdepartmental Center of Bioactive Peptide, University of Naples Federico II, Via Mezzocannone 16, 80134 Naples, Italy.; Center for Life Sciences and Technologies (CESTEV), University of Naples Federico II, Via De Amicis 95, 80145 Naples, Italy., Gentile MT; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania-Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy., Malgieri G; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania-Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy., Isernia C; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania-Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy., Saviano M; Institute of Crystallography, CNR, URT Caserta, Via Vivaldi 43, 81100 Caserta, Italy., Fattorusso R; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania-Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy., Zaccaro L; Institute of Biostructures and Bioimaging, CNR, Via Castellino 101, 80131 Naples, Italy.; Interdepartmental Center of Bioactive Peptide, University of Naples Federico II, Via Mezzocannone 16, 80134 Naples, Italy., Russo L; Department of Environmental, Biological and Pharmaceutical Science and Technology, University of Campania-Luigi Vanvitelli, Via Vivaldi 43, 81100 Caserta, Italy.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Sep 20; Vol. 23 (19). Date of Electronic Publication: 2022 Sep 20.

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Akademický článek

Benzodifurans for biomedical applications: BZ4, a selective anti-proliferative and anti-amyloid lead compound.

Autor: Vicidomini C; CNR, Institute of Biostructure & Bioimaging, Via Mezzocannone site & Headquarters, 80134 Naples, Italy., Cioffi F; Nanobiophysics, Faculty of Science & Technology (TNW), Technical Medical Centre, University of Twente, The Netherlands., Broersen K; Nanobiophysics, Faculty of Science & Technology (TNW), Technical Medical Centre, University of Twente, The Netherlands., Roviello V; Advanced Metrologic Service Center (CeSMA), University of Naples Federico II, Corso N. Protopisani, 80146 Naples, Italy., Riccardi C; Department of Chemical Sciences, University of Naples Federico II, Via Cintia 21, 80126 Naples, Italy., Montesarchio D; Department of Chemical Sciences, University of Naples Federico II, Via Cintia 21, 80126 Naples, Italy., Capasso D; Department of Pharmacy, University of Naples Federico II, Via Mezzocannone 16, 80134 Naples, Italy., Gaetano SD; CNR, Institute of Biostructure & Bioimaging, Via Mezzocannone site & Headquarters, 80134 Naples, Italy., Musumeci D; CNR, Institute of Biostructure & Bioimaging, Via Mezzocannone site & Headquarters, 80134 Naples, Italy.; Department of Chemical Sciences, University of Naples Federico II, Via Cintia 21, 80126 Naples, Italy., Roviello GN; CNR, Institute of Biostructure & Bioimaging, Via Mezzocannone site & Headquarters, 80134 Naples, Italy.

Publikováno v: Future medicinal chemistry [Future Med Chem] 2019 Feb; Vol. 11 (4), pp. 285-302. Date of Electronic Publication: 2019 Feb 25.

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