Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Gaetano Clavenna"'
Autor:
Gianfranco Caselli, M. Gentile, Gaetano Clavenna, Gabriella Melillo, Paola Maffei, Giancarlo Ceschel, M. C. Dragani, Porzio Stefano
Publikováno v:
Drug Delivery. 9:259-263
Thiocolchicoside, a muscle relaxant agent with anti-inflammatory and analgesic actions, also is used topically for the treatment of muscular spasms and for rheumatologic, orthopedic, and traumatologic disorders. In this study, thiocolchicoside was fo
Autor:
Marcello Allegretti, Wilma Sabbatini, Gandolfi Carmelo A, Pellegrini Luigi, Roberto Anacardio, Giancarlo Sciortino, Gabriella Melillo, Gaetano Clavenna, Gianfranco Caselli, Simonetta Fiorentino, Marco Mantovanini, Anna Teti, Riccardo Bertini
Publikováno v:
Journal of Bone and Mineral Research. 12:972-981
In the search for a new class of bone-sparing agents for treating osteopenic disorders, we hypothesized that tartronic acid derivatives, sharing the chemical characteristics both of bisphosphonates and of Gla residues contained in matrix proteins suc
Autor:
G. Fedele, E Mainetti, Simonetta Fiorentino, Gianfranco Caselli, Gaetano Clavenna, C D'Agostino, Gabriella Melillo
Publikováno v:
Pharmacological Research. 33:277-281
Immobilization and the consequent unloading can cause osteopenia both in humans and in animals due to an increased bone resorption and a parallel reduction in bone formation. Non-steroidal anti-inflammatory drugs (NSAIDs), and in particular the aryl
Autor:
Luisa Daffonchio, C. Asti, C. Omini, A. Hernandez, Gaetano Clavenna, Gabriella Melillo, Gianfranco Caselli
Publikováno v:
Pharmacological Research. 31:387-392
We investigated the possible effects of the mucoactive drug Carbocysteine lysine salt monohydrate (CLS.H2O) on experimentally-induced airway inflammation and hyperresponsiveness. CLS.H2O given by the oral route (300 mg kg(-1)) significantly reduced n
Publikováno v:
European Journal of Pharmacology: Environmental Toxicology and Pharmacology. 228:257-261
We verified the possible effect of the new antitussive drug levodropropizine on airway hyperreactivity and lung inflammation induced by cigarette smoke exposure in anaesthetized guinea-pigs. Levodropropizine, administered by aerosol at 25 mg/ml for 3
Publikováno v:
Agents and Actions. 33:181-184
The nature of histamine receptors in peripheral tissues is still controversial. However, evidence of heterogeneous classes of binding sites for [3H]-mepyramine are reported in the literature. The aim of our study was, therefore, to investigate the na
Publikováno v:
European Journal of Pharmacology. 187:19-25
Esaprazole, N-cyclohexyl-1-piperazineacetamide monohydrochloride, was studied for its activity to prevent gastric mucosal damage induced by several necrotizing agents in the rat. Its effects on acid gastric secretion and the role of gastric mucosal p
Publikováno v:
Pulmonary Pharmacology. 3:145-150
We have investigated the changes in airway reactivity induced in guinea-pigs by passive cigarette smoke exposure. In particular, we studied the development of airway hyperresponsiveness both in vivo and in vitro after passive exposure of the animals
Autor:
Gianfranco Caselli, Gaetano Clavenna, M. Gentile, Pellegrini Luigi, Porzio Stefano, A Coppola, L Boltri, Gabriella Melillo, M Del Rosario, Valentina Pallottini
Publikováno v:
Pharmacological research. 37(1)
The aim of this study was to evaluate the percutaneous permeation of a new topical Gel-Spray formulation, containing 15% of ketoprofen lysine salt (KLS), both in vitro, using the Franz-type diffusion cells and in vivo, by evaluating urinary recovery
Publikováno v:
Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 45(5)
We investigated the capacity of ketoprofen lysine salt (KLS) to counteract the pulmonary effects of some mediators of airway inflammation. The protective effect of KLS and its R-isomer against bradykinin (BK) induced plasma extravasation in the airwa