Stabilized Arylzinc Iodides in Negishi Acylative Cross-Coupling: A Modular Synthesis of Chalcones

Autor: Michele Pierigé, Anna Iuliano, Gaetano Angelici, Gianluca Casotti

Publikováno v: Organics, Vol 3, Iss 2, Pp 87-94 (2022)

Stabilized arylzinc iodides, synthesized by direct insertion of zinc into the corresponding halides, were used as nucleophiles into an acylative Negishi coupling reaction to synthesize chalcones. The reaction conditions were optimized to afford optim

Externí odkaz: https://doaj.org/article/564d63daac15462e90a8ef4d79f9dfb3

A Unique and Stable Polyproline I Helix Sorted out from Conformational Equilibrium by Solvent Polarity

Autor: Matteo Pollastrini, Luca Pasquinelli, Marcin Górecki, Federica Balzano, Lorenzo Cupellini, Filippo Lipparini, Gloria Uccello Barretta, Fabio Marchetti, Gennaro Pescitelli, Gaetano Angelici

Publikováno v: The Journal of Organic Chemistry. 87:13715-13725

Polyproline I helical structures are often considered as the hidden face of their most famous geminal sibling, Polyproline II, as PPI is generally spotted only within a conformational equilibrium. We designed and synthesized a stable Polyproline I st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd4e7ef35c37e3cc96ba21887e2fa9a
https://doi.org/10.1021/acs.joc.2c01377

Total Synthesis of Asparenydiol by Two Sonogashira Cross-Coupling Reactions Promoted by Supported Pd and Cu Catalysts

Autor: Gianluca Casotti, Graziano Fusini, Claudio Evangelisti, Matteo Ferreri, Luca Pardini, Adriano Carpita, Gaetano Angelici

Publikováno v: Synthesis (Stuttg.) 52 (2020): 1795–1803. doi:10.1055/s-0039-1690852
info:cnr-pdr/source/autori:Casotti G.; Fusini G.; Ferreri M.; Pardini L.F.; Evangelisti C.; Angelici G.; Carpita A./titolo:Total Synthesis of Asparenydiol by Two Sonogashira Cross-Coupling Reactions Promoted by Supported Pd and Cu Catalysts/doi:10.1055%2Fs-0039-1690852/rivista:Synthesis (Stuttg.)/anno:2020/pagina_da:1795/pagina_a:1803/intervallo_pagine:1795–1803/volume:52

Asparenydiol, which is an important natural compound with potential pharmacological activities, was synthesized through two Sonogashira­ cross-coupling reactions catalyzed by supported Pd and Cu catalysts and by a Mitsunobu etherification. The optim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe07e6d7d9604e6aee6a2010faf9f4e6
https://doi.org/10.1055/s-0039-1690852

Synthesis of Pterostilbene through supported-catalyst promoted Mizoroki-Heck reaction, and its transposition in continuous flow reactor

Autor: Gianluca Casotti, Gabriele Laudadio, Gaetano Angelici, Adriano Carpita, Graziano Fusini, Claudio Evangelisti

Publikováno v: Journal of Flow Chemistry, 9(2), 133-143. Akademiai Kiadó

Pterostilbene, an important polyphenolic compound with interesting biological activities, has been efficiently synthesized through a Mizoroki-Heck reaction catalyzed by commercially available Pd catalysts immobilized onto heterogeneous supports. The

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ca8752b0aac608cf184ed70ba993caa
https://doi.org/10.1007/s41981-019-00033-0

A Proline Mimetic for the Design of New Stable Secondary Structures: Solvent-Dependent Amide Bond Isomerization of (

Autor: Matteo, Pollastrini, Filippo, Lipparini, Luca, Pasquinelli, Federica, Balzano, Gloria Uccello, Barretta, Gennaro, Pescitelli, Gaetano, Angelici

Publikováno v: The Journal of Organic Chemistry

A thorough experimental and computational study on the conformational properties of (S)-indoline-2-carboxylic acid derivatives has been conducted. Methyl (S)-1-acetylindoline-2-carboxylate, both a mimetic of proline and phenylalanine, shows a remarka

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::818c435a6dd32b9d2cf4476559b1d7f6
https://pubmed.ncbi.nlm.nih.gov/34080867