Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Gaetana Serio"'
Autor:
Irene Schiano Lomoriello, Giovanni Giangreco, Claudia Iavarone, Chiara Tordonato, Giusi Caldieri, Gaetana Serio, Stefano Confalonieri, Stefano Freddi, Fabrizio Bianchi, Stefania Pirroni, Giovanni Bertalot, Giuseppe Viale, Davide Disalvatore, Daniela Tosoni, Maria Grazia Malabarba, Andrea Disanza, Giorgio Scita, Salvatore Pece, Brian K. Pilcher, Manuela Vecchi, Sara Sigismund, Pier Paolo Di Fiore
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
It is unclear if genetic alterations in endocytic proteins play a causal role in high incidence human cancers. Here, the authors report the oncogenic role of Epsin3 (EPN3) in breast cancer, and show EPN3 to drive tumorigenesis through induction of a
Externí odkaz:
https://doaj.org/article/13d80ead99db4faeaae47bea7bd4c693
Autor:
Sara Sigismund, Giuseppe Viale, Salvatore Pece, Claudia Iavarone, Maria Grazia Malabarba, Giovanni Giangreco, Pier Paolo Di Fiore, Chiara Tordonato, Fabrizio Bianchi, Giovanni Bertalot, Gaetana Serio, Stefano Freddi, Brian K. Pilcher, Manuela Vecchi, Stefania Pirroni, Giorgio Scita, Andrea Disanza, Davide Disalvatore, Giusi Caldieri, Stefano Confalonieri, Irene Schiano Lomoriello, Daniela Tosoni
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
The subversion of endocytic routes leads to malignant transformation and has been implicated in human cancers. However, there is scarce evidence for genetic alterations of endocytic proteins as causative in high incidence human cancers. Here, we repo
Autor:
Letizia Lanzetti, Jiri Bartek, Federico Bussolino, Valentina Margaria, Gaetana Serio, Amanda Oldani, Sanne B. Jensen
Publikováno v:
Proceedings of the National Academy of Sciences; Vol 108
Rab5 is a small GTPase known to regulate vesicular trafficking during interphase. Here, we show that Rab5 also plays an unexpected role during mitotic progression. RNAi-mediated silencing of Rab5 caused defects in chromosome congression and extensive
Autor:
Giovanni Spinelli, Gaetana Serio, Domenica Di Caro, Claudia Alessandro, Valentina Di Caro, Franco Palla, Vincenzo Cavalieri, Raffaella Melfi
Publikováno v:
Journal of molecular biology. 342(5)
The tandem repeated sea urchin alpha-histone genes are developmentally regulated by gene-specific promoter elements. Coordinate transcription of the five genes begins after meiotic maturation of the oocyte, continues through cleavage, and reaches its