Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Gaetan Siriez"'
Autor:
Frédéric Delouvroy, Laetitia Malphettes, An-Vy Tran, Gaetan Siriez, Nadine Kochanowski, Larissa Mukankurayija
Publikováno v:
BMC Proceedings
Background Enhancing throughput of bioprocess development has become increasingly important to rapidly screen and optimize cell culture process parameters. With increasing timeline pressures to get therapeutic candidates into the clinic, resource int
Publikováno v:
BMC Proceedings, Vol 5, Iss Suppl 8, p P75 (2011)
BMC Proceedings
BMC Proceedings
Background Mammalian cells are used extensively in the production of recombinant proteins, and of monoclonal antibodies (MAbs) in particular. The trend towards avoiding animal-derived components in biopharmaceutical production processes has led to th
Host cell protein platform assay development for therapeutic mAb bioprocessing using mammalian cells
Autor:
Clemens Stilling, Laetitia Malphettes, Nadja Prang, Nadine Kochanowski, Larissa Mukankurayija, David Mainwaring, Gaetan Siriez, Alex Murray-Smith, Aurélie Delangle, Kevin Dromer, Annick Gervais
Publikováno v:
BMC Proceedings
Background Recombinant therapeutic proteins are usually produced by cell culture technology using genetically modified host cell lines. During the manufacturing process, a mixture of the protein of interest and host cell derived impurities, including