Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Gaetan Ladouceur"'
Autor:
Anthony M. Treston, Gregory E. Agoston, LiQuan Wang, Gaetan Ladouceur, Zhenglai Fang, Mark Cushman
Publikováno v:
Tetrahedron. 65:10535-10543
ENMD-1198 is a biologically active analogue of the antitumor drug 2-methoxyestradiol. Four human metabolites of ENMD-1198 were identified through synthesis and liquid chromatography/mass spectrometry comparisons of the metabolites with the synthetic
Autor:
Jun Yang, Xiaoping Jiang, Stephanie Aungst, Anshu Marathe, Liang Zhou, Hong Zhao, Richard Pazdur, Gaetan Ladouceur, Abhilasha Nair, Liang Zhao, Amit K. Mitra, Whitney S. Helms, Kun He, Patricia Keegan, Emily Fox, Steven Lemery
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 21(23)
The FDA approved lenvatinib (Lenvima, Eisai Inc.) for the treatment of patients with locally recurrent or metastatic, progressive, radioactive iodine-refractory (RAI-refractory) differentiated thyroid cancer (DTC). In an international, multicenter, d
Autor:
Amna Ibrahim, Elimika Pfuma, Gaetan Ladouceur, Hui Zhang, Anne Marie Russell, Haw-Jyh Chiu, Todd R. Palmby, Rajeshwari Sridhara, Thomas Gwise, Rajesh Venugopal, Shenghui Tang, Amy E. McKee, Abraham Tzou, Liang Zhao, Eunice Y. Lee, Reena Philip, Tiffany K. Ricks, Richard Pazdur, Gwynn Ison, Qi Liu, Hongshan Li, Geoffrey Kim
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 21(19)
On December 19, 2014, the FDA approved olaparib capsules (Lynparza; AstraZeneca) for the treatment of patients with deleterious or suspected deleterious germline BRCA-mutated (gBRCAm) advanced ovarian cancer who have been treated with three or more p
Synthesis and evaluation of [125I]-(S)-iodozacopride, a high affinity radioligand for 5HT3 receptors
Autor:
Dale E. Mais, Gaetan Ladouceur, Douglas A. Schober, Donald R. Gehlert, David W. Robertson, Susan L. Gackenheimer
Publikováno v:
Neurochemistry International. 23:373-383
We have developed a high specific activity radioiodinated ligand for the biochemical evaluation and autoradiographic localization of 5HT3 receptors in the brain. [ 125 I ]-(S)- iodozacopride was synthesized by radioiodination of deschloro-(S)-zacopri
Autor:
Gaetan Ladouceur, Leo A. Paquette
Publikováno v:
Synthesis. 1992:185-191
Methodology is described for expedient synthesis of the A/B framework of 8,9-seco-ent-kaurenes and for introduction of the 5-methylene-2-cyclopentenone moiety. In the first part of the study, a sequence of only six steps is necessary to convert 2-(hy
Autor:
Leo A. Paquette, Gaetan Ladouceur
Publikováno v:
The Journal of Organic Chemistry. 54:4278-4279