Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Gaetan Chicanne"'
Autor:
Xènia Massana-Muñoz, Marie Goret, Vasugi Nattarayan, David Reiss, Christine Kretz, Gaetan Chicanne, Bernard Payrastre, Bart Vanhaesebroeck, Jocelyn Laporte
Publikováno v:
JCI Insight, Vol 8, Iss 9 (2023)
Phosphoinositides (PIs) are membrane lipids that regulate signal transduction and vesicular trafficking. X-linked centronuclear myopathy (XLCNM), also called myotubular myopathy, results from loss-of-function mutations in the MTM1 gene, which encodes
Externí odkaz:
https://doaj.org/article/7c87ab32f731424ea2d18197b699faec
Publikováno v:
Current topics in microbiology and immunology. 436
Highly conserved from yeast to mammals, vacuolar protein sorting 34 (Vps34) is the sole member of the third class of the phosphoinositide 3-kinase (PI3K) family. By producing phosphatidylinositol-3-monophosphate (PtdIns3P) through its scaffolding fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::45d2c6e0a99af2d5b03cd46b0e9500e8
https://pubmed.ncbi.nlm.nih.gov/36243840
https://pubmed.ncbi.nlm.nih.gov/36243840
Publikováno v:
Current Topics in Microbiology and Immunology ISBN: 9783031065651
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::674fdf11c459f7383bd72e5b52168d30
https://doi.org/10.1007/978-3-031-06566-8_3
https://doi.org/10.1007/978-3-031-06566-8_3
Autor:
Gaëtan Chicanne, Jean Darcourt, Justine Bertrand-Michel, Cédric Garcia, Agnès Ribes, Bernard Payrastre
Publikováno v:
Platelets, Vol 34, Iss 1 (2023)
Besides their proteome, platelets use, in all responses to the environmental cues, a huge and diverse family of hydrophobic and amphipathic small molecules involved in structural, metabolic and signaling functions; the lipids. Studying how platelet l
Externí odkaz:
https://doaj.org/article/0960a3360c0242c390284ba6f8facd7b
Autor:
Antoine Oprescu, Déborah Michel, Adrien Antkowiak, Elodie Vega, Julien Viaud, Sara A. Courtneidge, Anita Eckly, Henri de la Salle, Gaëtan Chicanne, Catherine Léon, Bernard Payrastre, Frédérique Gaits-Iacovoni
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Bone marrow megakaryocytes (MKs) undergo a maturation involving contacts with the microenvironment before extending proplatelets through sinusoids to deliver platelets in the bloodstream. We demonstrated that MKs assemble linear F-actin-enri
Externí odkaz:
https://doaj.org/article/3c534a032d894f3da7e0844798600b5c
Autor:
Yu Wu, Nassim Mahtal, Eléa Paillares, Léa Swistak, Sara Sagadiev, Mridu Acharya, Caroline Demeret, Sylvie Van Der Werf, Florence Guivel-Benhassine, Olivier Schwartz, Serena Petracchini, Amel Mettouchi, Lucie Caramelle, Pierre Couvineau, Robert Thai, Peggy Barbe, Mathilde Keck, Priscille Brodin, Arnaud Machelart, Valentin Sencio, François Trottein, Martin Sachse, Gaëtan Chicanne, Bernard Payrastre, Florian Ville, Victor Kreis, Michel-Robert Popoff, Ludger Johannes, Jean-Christophe Cintrat, Julien Barbier, Daniel Gillet, Emmanuel Lemichez
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104537- (2022)
Summary: The development of anti-infectives against a large range of AB-like toxin-producing bacteria includes the identification of compounds disrupting toxin transport through both the endolysosomal and retrograde pathways. Here, we performed a hig
Externí odkaz:
https://doaj.org/article/a1115a643e6e4c1fb159e5c28cc1dc8c
Autor:
Abdulrahman Mujalli, Julien Viaud, Sonia Severin, Marie-Pierre Gratacap, Gaëtan Chicanne, Karim Hnia, Bernard Payrastre, Anne-Dominique Terrisse
Publikováno v:
Biomolecules, Vol 13, Iss 4, p 583 (2023)
Phosphoinositides (PIs) play a crucial role in regulating intracellular signaling, actin cytoskeleton rearrangements, and membrane trafficking by binding to specific domains of effector proteins. They are primarily found in the membrane leaflets faci
Externí odkaz:
https://doaj.org/article/8bf7234329ed485abc94a2e26f66bf70
Autor:
Sonia Severin, Alessandra Consonni, Gaëtan Chicanne, Sophie Allart, Bernard Payrastre, Marie-Pierre Gratacap
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 958 (2023)
The Src homology 2 domain-containing inositol 5-phosphatase 1 (SHIP1) is known to dephosphorylate PtdIns(3,4,5)P3 into PtdIns(3,4)P2 and to interact with several signaling proteins though its docking functions. It has been shown to negatively regulat
Externí odkaz:
https://doaj.org/article/e5a65ef8b94c43c2903ef38c8d6b6203
Autor:
Gaëtan Chicanne, Maria N. Barrachina, Anaelle Durbec, Justine Bertrand-Michel, Sara Troitiño, Lidia Hermida-Nogueira, Aurelio M. Sueiro, María Pardo, Bernard Payrastre, Ángel García
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8326 (2022)
Obesity is associated with a pro-inflammatory and pro-thrombotic state that supports atherosclerosis progression and platelet hyper-reactivity. During the last decade, the platelet lipidome has been considered a treasure trove, as it is a source of b
Externí odkaz:
https://doaj.org/article/7b03e54e30be47b29e5e41a944e41a04
Autor:
Benoit Bilanges, Samira Alliouachene, Wayne Pearce, Daniele Morelli, Gyorgy Szabadkai, Yuen-Li Chung, Gaëtan Chicanne, Colin Valet, Julia M. Hill, Peter J. Voshol, Lucy Collinson, Christopher Peddie, Khaled Ali, Essam Ghazaly, Vinothini Rajeeve, Georgios Trichas, Shankar Srinivas, Claire Chaussade, Rachel S. Salamon, Jonathan M. Backer, Cheryl L. Scudamore, Maria A. Whitehead, Erin P. Keaney, Leon O. Murphy, Robert K. Semple, Bernard Payrastre, Sharon A. Tooze, Bart Vanhaesebroeck
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Vps34 is a lipid kinase conserved from yeast to humans and involved in in intracellular vesicular trafficking and autophagy. Here Bilanges et al. show that inhibition of this kinase in mice improves glucose tolerance and diet-induced steatosis by mod
Externí odkaz:
https://doaj.org/article/555f2b0adcb149a18a070a3da3035320