Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Gaelle Rondeau"'
Autor:
Yipeng Wang, Qiuju Yu, Ann H. Cho, Gaelle Rondeau, John Welsh, Eileen Adamson, Dan Mercola, Michael McClelland
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 8, Pp 748-760 (2005)
DNA methylation, copy number in the genomes of three immortalized prostate epithelial, five cancer cell lines (LNCaP, PC3, PC3M, PC3M-Pro4, PC3MLN4) were compared using a microarray-based technique. Genomic DNA is cut with a methylation-sensitive enz
Externí odkaz:
https://doaj.org/article/9e7c94292a25440ea57a51d7b2fcbb35
Autor:
Gaelle Rondeau, Parisa Abedinpour, Prerak Desai, Veronique T Baron, Per Borgstrom, John Welsh
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101160 (2014)
In metastasis, circulating tumor cells penetrate the walls of blood vessels and enter the metastatic target tissue, thereby becoming exposed to novel and relatively unsupportive microenvironments. In the new microenvironments, the tumor cells often r
Externí odkaz:
https://doaj.org/article/7602efcb5e3343c09867ef6b1a93aee0
Autor:
Li Bie, Gang Zhao, Pui Cheng, Gaelle Rondeau, Steffen Porwollik, Yan Ju, Xiao-Qin Xia, Michael McClelland
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25631 (2011)
Identification of gene expression changes that improve prediction of survival time across all glioma grades would be clinically useful. Four Affymetrix GeneChip datasets from the literature, containing data from 771 glioma samples representing all WH
Externí odkaz:
https://doaj.org/article/6746949db7d14a928a272f3210eb4f36
Autor:
John Welsh, Parisa Abedinpour, Véronique Baron, Adrian Chrastina, Gaelle Rondeau, Per Borgstrom
Publikováno v:
ChemMedChem. 15:1338-1347
Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) is a small molecule with potent anticancer activity. Like other 1,4-naphthoquinones, it exhibits electrophilic reactivity towards biological nucleophiles. We demonstrate that plumbagin and structurall
Autor:
Per Borgstrom, Gaelle Rondeau, Parisa Abedinpour, Adrian Chrastina, John Welsh, Jennifer Pelayo
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
Scientific Reports
Treatment of mice harboring PTEN-P2 tumors in the prostate or on prostate tissue in vivo with 5-hydroxy-2-methyl-1,4-naphthoquinone, also known as plumbagin, results in tumor regression in castrated mice, but not in intact mice. This suggested that d
Autor:
John Welsh, Adrian Chrastina, Gaelle Rondeau, Véronique Baron, Per Borgström, Parisa Abedinpour
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2018 (2018)
BioMed Research International, Vol 2018 (2018)
Background. Plumbagin, a medicinal plant-derived 5-hydroxy-2-methyl-1,4-naphthoquinone, is an emerging drug with a variety of pharmacological effects, including potent anticancer activity. We have previously shown that plumbagin improves the efficacy
Autor:
Adrian Chrastina, Per Borgström, Parisa Abedinpour, John Welsh, Gaelle Rondeau, Jennifer Pelayo, Véronique Baron
Publikováno v:
The Prostate. 77(16)
Background Plumbagin is a candidate drug for the treatment of prostate cancer. Previous observations indicated that it may improve the efficacy of androgen deprivation therapy (ADT). This study evaluates the effectiveness of treatment with combinatio
Publikováno v:
International Journal of Medical Microbiology. 303:210-216
E. coli is generally a commensal but includes some highly pathogenic strains carrying additional genes in plasmids and/or the chromosome. Based on these genes the pathogenic strains are divided into pathotypes including enteropathogenic (EPEC), enter
Autor:
Xiangyue Wu, Christi Tempesta, Aparna Kishor, Yufang Shi, Gaelle Rondeau, Naznin Daginawala, John Welsh, Mei-Ling Li, Guangwu Xu, Patricia Irizarry-Barreto, Reshma Patel, Gerald M. Wilson, Gary Brewer, Sandy Charles, Beth E. Zucconi, Sandra Chesoni
Publikováno v:
Nucleic Acids Research
The RNA-binding protein AUF1 binds AU-rich elements in 3'-untranslated regions to regulate mRNA degradation and/or translation. Many of these mRNAs are predicted microRNA targets as well. An emerging theme in post-transcriptional control of gene expr
Autor:
Mark E. Berrang, Fred Long, John Barrett, Johnnie A. Davis, S. N. Thitaram, Michael McClelland, Jonathan G. Frye, Mark D. Englen, Richard J. Meinersmann, Jennifer B. Turpin, Gaelle Rondeau, Charlene R. Jackson, Paula J. Fedorka-Cray, Steffen Porwollik, Rebecca L. Lindsey
Publikováno v:
Microbial Drug Resistance. 16:9-19
To understand the mechanisms and epidemiology of antimicrobial resistance (AR), the genetic elements responsible must be identified. Due to the myriad of possible genes, a high-density genotyping technique is needed for initial screening. To achieve