Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Gaelle Muller-Greven"'
Autor:
Wei Michael Liu, Ping Huang, Niladri Kar, Monica Burgett, Gaelle Muller-Greven, Amy S Nowacki, Clark W Distelhorst, Justin D Lathia, Jeremy N Rich, John C Kappes, Candece L Gladson
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70804 (2013)
Members of the Src family kinases (SFK) can modulate diverse cellular processes, including division, death and survival, but their role in autophagy has been minimally explored. Here, we investigated the roles of Lyn, a SFK, in promoting the survival
Externí odkaz:
https://doaj.org/article/28a1bcb0b36d4560a0b45c51242afaef
Publikováno v:
Cancer Research. 83:4593-4593
Glioblastoma (GBM) is the most common primary brain tumor in adults with a 15-month median survival, despite surgical-resection and radio-chemotherapy, and a recurrence rate of 90%. Despite improving survival in only a small percentage of patients, b
Autor:
Lingling Du, Manmeet Ahluwalia, Robert J. Weil, Maha A. Qadan, Amy S. Nowacki, Ruth A. Keri, Nooshin Hashemi-Sadraei, Gaelle Muller-Greven, Thomas Budd, Richard A. Prayson, Candece L. Gladson, Monica E. Burgett, Ilya V. Ulasov, Adam Lauko, Fadi W. Abdul-Karim, Jill S. Barnholtz-Sloan, Erinn Downs-Kelly, Samuel T. Chao
Publikováno v:
Journal of Neuro-Oncology. 140:237-248
Macroautophagy/autophagy is considered to play key roles in tumor cell evasion of therapy and establishment of metastases in breast cancer. High expression of LC3, a residual autophagy marker, in primary breast tumors has been associated with metasta
Autor:
Gaelle Muller-Greven, Jeongwu Lee, Candece L. Gladson, Bianca-Maria Marin, Edward Reilly, Cathleen R. Carlin, M. Bredel, Jann N. Sarkaria
Publikováno v:
Neuro-Oncology. 20:vi283-vi284
Therapy with ABT-414 (depatux-m), a humanized monoclonal antibody drug conjugate (ADC) directed toward EGFRvIII and activated wild-type EGFR linked to MMAF, has demonstrated promising clinical activity in glioblastoma (GBM) patients with amplified EG
Autor:
Manmeet Ahluwalia, Justin D. Lathia, Maha A. Qadan, Cameron Herting, Amy S. Nowacki, Steven A. Toms, Dolores Hambardzumyan, Gaelle Muller-Greven, Adam Lauko, Petra Hamerlik, Markus Bredel, Monica E. Burgett, Jann N. Sarkaria, Cathleen R. Carlin, Candece L. Gladson
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 23(22)
Purpose: Bevacizumab, a humanized monoclonal antibody to VEGF, is used routinely in the treatment of patients with recurrent glioblastoma (GBM). However, very little is known regarding the effects of bevacizumab on the cells in the perivascular space
Autor:
Justin D. Lathia, Petra Hamerlik, Gaelle Muller-Greven, Candece L. Gladson, Manmeet Ahluwalia, Markus Bredel, Steven A. Toms, Cathleen R. Carlin, Jeremy N. Rich
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390bdc9fd8267e732f653e37e3564eb5
https://europepmc.org/articles/PMC4639244/
https://europepmc.org/articles/PMC4639244/
Autor:
Manmeet Ahluwalia, Petra Hamerlik, Steven A. Toms, Justin D. Lathia, Gaelle Muller-Greven, Markus Bredel, Candece L. Gladson, Jeremy N. Rich, Cathleen R. Carlin
Publikováno v:
Neuro-Oncology. 18:vi188-vi189
Autor:
Gaelle Muller-Greven, Cathleen R. Carlin, Jeremy N. Rich, Justin D. Lathia, Candece L. Gladson, Petra Hamerlik
Antiangiogenic therapy shows great promise for treatment of cancer. Bevacizumab is a humanized mAb that blocks VEGF-A, thereby inhibiting angiogenesis. It has received FDA approval for patients with recurrent glioblastoma (GBM); however, approximatel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe0492a1b5ba6dd7406dedc489f6a2f1
https://europepmc.org/articles/PMC4218582/
https://europepmc.org/articles/PMC4218582/
Autor:
Gaelle Muller-Greven, Jeremy N. Rich, Wei Michael Liu, Amy S. Nowacki, Monica E. Burgett, Candece L. Gladson, Ping Huang, Clark W. Distelhorst, John C. Kappes, Niladri S. Kar, Justin D. Lathia
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 8, p e70804 (2013)
PLoS ONE, Vol 8, Iss 8, p e70804 (2013)
Members of the Src family kinases (SFK) can modulate diverse cellular processes, including division, death and survival, but their role in autophagy has been minimally explored. Here, we investigated the roles of Lyn, a SFK, in promoting the survival
Autor:
Petra Hamerlik, Manmeet Ahluwalia, Jeremy N. Rich, Cathleen R. Carlin, Justin D. Lathia, Markus Bredel, Gaelle Muller-Greven, Steven A. Toms, Candece L. Gladson
Publikováno v:
Cancer Research. 76:3276-3276
Most patients with recurrent glioblastoma (GBM) are treated with bevacizumab, a humanized monoclonal antibody (mAb) that binds VEGF-A and inhibits its binding to VEGFR. Approximately 30% of GBM patients are non-responsive to bevacizumab and the under