Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Gaelle Filhoulaud"'
Autor:
Gaelle Filhoulaud, Fadila Benhamed, Patrick Pagesy, Caroline Bonner, Yann Fardini, Anissa Ilias, Jamileh Movassat, Anne-Françoise Burnol, Sandra Guilmeau, Julie Kerr-Conte, François Pattou, Tarik Issad, Catherine Postic
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Thioredoxin interacting protein (TxNIP), which strongly responds to glucose, has emerged as a central mediator of glucotoxicity in pancreatic β cells. TxNIP is a scaffold protein interacting with target proteins to inhibit or stimulate their activit
Externí odkaz:
https://doaj.org/article/9c5a66758ef54b9384f0c41f8fdc18bd
Publikováno v:
Trends in endocrinology and metabolism: TEM. 24(5)
Glucose is an energy source that also controls the expression of key genes involved in energetic metabolism through the glucose-signaling transcription factor carbohydrate response element-binding protein (ChREBP). ChREBP has recently emerged as a ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7770dbc8ddbb5f72ba3b134470227a19
https://pubmed.ncbi.nlm.nih.gov/23597489
https://pubmed.ncbi.nlm.nih.gov/23597489
Autor:
Benedicte Noblet, Fadila Benhamed, InSug O-Sullivan, Wenwei Zhang, Gaëlle Filhoulaud, Alexandra Montagner, Arnaud Polizzi, Solenne Marmier, Anne-Françoise Burnol, Sandra Guilmeau, Tarik Issad, Hervé Guillou, Catherine Bernard, Terry Unterman, Catherine Postic
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102218- (2021)
Summary: TxNIP (Thioredoxin-interacting protein) is considered as a potential drug target for type 2 diabetes. Although TxNIP expression is correlated with hyperglycemia and glucotoxicity in pancreatic β cells, its regulation in liver cells has been
Externí odkaz:
https://doaj.org/article/54c26cec1c3f4bb594dcc0aa898781ca