Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Gaelle Chaffard"'
Publikováno v:
Pflügers Archiv, Vol. 471, No 2 (2019) pp. 337-345
The clonal INS-1E beta-cell line has proven to be instrumental for numerous studies investigating the mechanisms of glucose-stimulated insulin secretion. The composition of its culture medium has not changed over the years, although some compounds ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::996fcb1a9910bdefd99aa3cc28c1dd13
https://archive-ouverte.unige.ch/unige:116615
https://archive-ouverte.unige.ch/unige:116615
Autor:
Dorothée Caille, Mitsunori Fukuda, Amar Abderrahmani, Romano Regazzi, J-A. Haefliger, Pierre Maechler, Paolo Meda, Florent Allagnat, Gérard Waeber, David C. Martin, Gaelle Chaffard
Publikováno v:
Diabetologia, vol. 51, no. 8, pp. 1429-1439
Diabetologia
Diabetologia, Vol. 51, No 8 (2008) pp. 1429-39
Diabetologia
Diabetologia, Vol. 51, No 8 (2008) pp. 1429-39
AIMS/HYPOTHESIS: The expression of several neuronal genes in pancreatic beta cells is due to the absence of the transcription factor repressor element 1 (RE-1) silencing transcription factor (REST). The identification of these traits and their functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e53ca32c87440f1e7af61a142692c94
https://doi.org/10.1007/s00125-008-0984-1
https://doi.org/10.1007/s00125-008-0984-1
Autor:
Claes B. Wollheim, Sten Theander, Blanca Rubi, Gaelle Chaffard, Arnaud Merglen, Pierre Maechler
Publikováno v:
Endocrinology, Vol. 145, No 2 (2004) pp. 667-78
Rat insulinoma-derived INS-1 cells constitute a widely used β-cell surrogate. However, due to their nonclonal nature, INS-1 cells are heterogeneous and are not stable over extended culture periods. We have isolated clonal INS-1E cells from parental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c60b2f11da5d456fa3f9a1df46d0706
https://doi.org/10.1210/en.2003-1099
https://doi.org/10.1210/en.2003-1099
Publikováno v:
Biochemical Journal, Vol. 424, No 3 (2009) pp. 459-466
Transfer of reducing equivalents between cytosolic compartments and the mitochondrial matrix is mediated by NADH shuttles. Among these, the malate–aspartate shuttle has been proposed to play a major role in β-cells for the control of glucose-stimu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70541be245754d37c5b5e4fd5569f54e
https://archive-ouverte.unige.ch/unige:19728
https://archive-ouverte.unige.ch/unige:19728
Publikováno v:
Biochemical pharmacology. 72(8)
Topiramate (Topamax), primarily prescribed against epilepsy, was reported to reduce body weight and to ameliorate glycemic control in obese patients with diabetes. In rodent models of obesity and diabetes, topiramate treatment counteracts hyperglycem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3414975de5652b36bff2f1ee0e781428
https://pubmed.ncbi.nlm.nih.gov/16934763
https://pubmed.ncbi.nlm.nih.gov/16934763
Publikováno v:
Biochemical Journal; Dec2009, Vol. 424 Issue 3, p459-466, 8p