Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Gaelle, Auguste"'
Autor:
Jordi Coste Pradas, Gaelle Auguste, Scot J. Matkovich, Raffaella Lombardi, Suet Nee Chen, Tyrone Garnett, Kyle Chamberlain, Jalish Mahmud Riyad, Thomas Weber, Sanjay K. Singh, Matthew J. Robertson, Cristian Coarfa, Ali J. Marian, Priyatansh Gurha
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 16 (2020)
Background Mutations in the LMNA gene, encoding LMNA (lamin A/C), causes distinct disorders, including dilated cardiomyopathies, collectively referred to as laminopathies. The genes (coding and noncoding) and regulatory pathways controlled by LMNA in
Externí odkaz:
https://doaj.org/article/30a260c5a89642f9bc7832cd03058595
Autor:
Leila, Rouhi, Gaelle, Auguste, Qiong, Zhou, Raffaella, Lombardi, Melis, Olcum, Kimia, Pourebrahim, Sirisha M, Cheedipudi, Saman, Asghar, Kui, Hong, Matthew J, Robertson, Cristian, Coarfa, Priyatansh, Gurha, Ali J, Marian
Publikováno v:
The journal of cardiovascular aging. 2(3)
Mutations in theThe purpose of the study was to determine the contribution of the fibroblasts to DCM caused by LMNA deficiency.TheDeletion of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e4c7bdba7f5de22f50df0c917b3cb19c
https://pubmed.ncbi.nlm.nih.gov/35891706
https://pubmed.ncbi.nlm.nih.gov/35891706
BET bromodomain inhibition attenuates cardiac phenotype in myocyte-specific lamin A/C–deficient mice
Autor:
Ali J. Marian, Matthew J. Robertson, Leila Rouhi, Gaelle Auguste, Priyatansh Gurha, Cristian Coarfa, Grazyna Czernuszewicz, Scot J. Matkovich
Publikováno v:
J Clin Invest
Mutation in the LMNA gene, encoding lamin A/C, causes a diverse group of diseases called laminopathies. Cardiac involvement is the major cause of death and manifests as dilated cardiomyopathy, heart failure, arrhythmias, and sudden death. There is no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e242d9a9609211192f5dfb069950b61a
https://doi.org/10.1172/jci135922
https://doi.org/10.1172/jci135922
Autor:
Wei Feng Ma, Euan A. Ashley, Johan L.M. Björkegren, Emily Farber, Soumya Kundu, Clint L. Miller, Sheng'en Hu, Thomas Quertermous, Anshul Kundaje, Lijiang Ma, Jason C. Kovacic, Aloke V. Finn, Chani J. Hodonsky, Adam W. Turner, Suna Onengut-Gumuscu, Nicholas J. Leeper, Jose Verdezoto Mosquera, Chongzhi Zang, Gaelle Auguste, Nicolas G. Lopez, Saikat Ghosh, Doris Wong, Katia Sol-Church
Coronary artery disease (CAD) is a complex inflammatory disease involving genetic influences across several cell types. Genome-wide association studies (GWAS) have identified over 170 loci associated with CAD, where the majority of risk variants resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6ae790cd5771f4a56ff3d13de3ab113
https://doi.org/10.1101/2021.06.07.447388
https://doi.org/10.1101/2021.06.07.447388
Autor:
James T. Willerson, Gaelle Auguste, Raffaella Lombardi, Priyatansh Gurha, Ali J. Marian, Cristian Coarfa
Publikováno v:
Circulation research. 122(5)
Rationale: Mutations in the LMNA gene, encoding nuclear inner membrane protein lamin A/C, cause distinct phenotypes, collectively referred to as laminopathies. Heart failure, conduction defects, and arrhythmias are the common causes of death in lamin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0cc3356225efd18b3a05517b07f9639
https://pubmed.ncbi.nlm.nih.gov/29496792
https://pubmed.ncbi.nlm.nih.gov/29496792
Publikováno v:
Circulation Research. 123
Lamin A/C (LMNA) is a major component of the nuclear membrane, involved in regulation of gene expression. Mutations in the LMNA gene cause a heterogeneous group of diseases, collectively referred to as laminopathies. Cardiac involvement is one of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d9cd0ccd86793f9a87b3e4a6a4f3b5a
https://doi.org/10.1161/res.123.suppl_1.232
https://doi.org/10.1161/res.123.suppl_1.232
Specific Activation of the Alternative Cardiac Promoter of Cacna1c by the Mineralocorticoid Receptor
Autor:
Marc Lombès, Angélica Rueda, Amaya Fernández-Celis, Rogelio Salazar-Enciso, Ana María Gómez, Sandra Lauton Santos, Susana Gomez, Débora Falcón, Patrick Lechêne, Gema Ruiz-Hurtado, Natalia López-Andrés, Eric Morel, Florence Lefebvre, Jessica Sabourin, Jean-Pierre Benitah, Gaelle Auguste, Thassio R. Mesquita, Valérie Nicolas, Say Viengchareun, Hussein Kobeissy
Publikováno v:
Circulation Research. 122
Rationale: The MR (mineralocorticoid receptor) antagonists belong to the current therapeutic armamentarium for the management of cardiovascular diseases, but the mechanisms conferring their beneficial effects are poorly understood. Part of the cardio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3409bd3817c9f1828a266b87dde06534
https://doi.org/10.1161/circresaha.117.312451
https://doi.org/10.1161/circresaha.117.312451
Autor:
Gema Ruiz-Hurtado, Jérôme Fagart, Florian Le-Billan, Jean-Pierre Benitah, Valérie Rouffiac, Eric Morel, Marc Lombès, Thassio R. Mesquita, Florence Lefebvre, Jessica Sabourin, Gaelle Auguste, Say Viengchareun, Ana Maria Gomez
Publikováno v:
Biophysical Journal. 110:438a-439a
Regulation of expression of the ubiquitous L-type Cav1.2 Ca2+ channels (encoded by the CaCNA1C gene) is critically involved in the pathogenesis of serious neurological, retinal, cardiac, vascular and metabolic disorders, in which the mineralocorticoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f70b48389cdf2081c289547c999cc5cc
https://doi.org/10.1016/j.bpj.2015.11.2365
https://doi.org/10.1016/j.bpj.2015.11.2365