Výsledky vyhledávání - "Gael, Boivin"

Akademický článek

Lung Organotypic Slices Enable Rapid Quantification of Acute Radiotherapy Induced Toxicity

Autor: Maxime Dubail, Sophie Heinrich, Lucie Portier, Jessica Bastian, Lucia Giuliano, Lilia Aggar, Nathalie Berthault, José-Arturo Londoño-Vallejo, Marta Vilalta, Gael Boivin, Ricky A. Sharma, Marie Dutreix, Charles Fouillade

Publikováno v: Cells, Vol 12, Iss 20, p 2435 (2023)

To rapidly assess healthy tissue toxicities induced by new anti-cancer therapies (i.e., radiation alone or in combination with drugs), there is a critical need for relevant and easy-to-use models. Consistent with the ethical desire to reduce the use

Externí odkaz: https://doaj.org/article/ef3dbdb660124597aecf336248a066ab

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Akademický článek

Durable and controlled depletion of neutrophils in mice

Autor: Gael Boivin, Julien Faget, Pierre-Benoit Ancey, Aspasia Gkasti, Julie Mussard, Camilla Engblom, Christina Pfirschke, Caroline Contat, Justine Pascual, Jessica Vazquez, Nathalie Bendriss-Vermare, Christophe Caux, Marie-Catherine Vozenin, Mikael J. Pittet, Matthias Gunzer, Etienne Meylan

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)

Anti-Ly6G or ant-Gr1 antibodies are commonly used to deplete neutrophils in vivo. Here the authors provide mechanistic insight into why these approaches may not specifically or durably reduce the number of neutrophils in mice, and also present a new

Externí odkaz: https://doaj.org/article/d3653b7e42a14239a9541459d01f0ce4

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Akademický článek

Neutrophils and Snail Orchestrate the Establishment of a Pro-tumor Microenvironment in Lung Cancer

Autor: Julien Faget, Svenja Groeneveld, Gael Boivin, Martial Sankar, Nadine Zangger, Miguel Garcia, Nicolas Guex, Inti Zlobec, Loïc Steiner, Alessandra Piersigilli, Ioannis Xenarios, Etienne Meylan

Publikováno v: Cell Reports, Vol 21, Iss 11, Pp 3190-3204 (2017)

Understanding the immune compartment of tumors facilitates the development of revolutionary new therapies. We used a Kras(G12D)-driven mouse model of lung cancer to establish an immune signature and identified a contribution of Gr1+ neutrophils to di

Externí odkaz: https://doaj.org/article/41248bbbba0546148e82ff48eaa672e0

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