Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Gadisetti V. R. Chandramouli"'
1
Data from Global Expression Profiling Identifies Signatures of Tumor Virulence in MMTV-PyMT-Transgenic Mice
Autor: Edison T. Liu, Jeffrey E. Green, Nawal W. Alkharouf, Kent W. Hunter, Gadisetti V. R. Chandramouli, Ting Hu Qiu
FVB/N-Tg (MMTV-PyMT)634Mul-transgenic mice develop multifocal mammary tumors with a high incidence of pulmonary metastasis. We have demonstrated previously that mammary tumors derived from transgene-positive F1 progeny in particular inbred strains di
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::292f0fad5ec9b4b8bc9d1477ec432869
https://doi.org/10.1158/0008-5472.c.6494007
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3
Akademický článek
Ornithine decarboxylase as a therapeutic target for endometrial cancer.
Autor: Hong Im Kim, Chad R Schultz, Andrea L Buras, Elizabeth Friedman, Alyssa Fedorko, Leigh Seamon, Gadisetti V R Chandramouli, G Larry Maxwell, André S Bachmann, John I Risinger
Publikováno v: PLoS ONE, Vol 12, Iss 12, p e0189044 (2017)
Ornithine Decarboxylase (ODC) a key enzyme in polyamine biosynthesis is often overexpressed in cancers and contributes to polyamine-induced cell proliferation. We noted ubiquitous expression of ODC1 in our published endometrial cancer gene array data
Externí odkaz: https://doaj.org/article/493769d495114577beac397315f42d7f
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4
Pharmacological targeting of polyamine and hypusine biosynthesis reduces tumour activity of endometrial cancer
Autor: Hong Im Kim, Chad R. Schultz, Gadisetti V. R. Chandramouli, Dirk Geerts, John I. Risinger, André S. Bachmann
Publikováno v: Journal of drug targeting, 30(6), 623-633
Kim, H I, Schultz, C R, Chandramouli, G V R, Geerts, D, Risinger, J I & Bachmann, A S 2022, ' Pharmacological targeting of polyamine and hypusine biosynthesis reduces tumour activity of endometrial cancer ', Journal of drug targeting, vol. 30, no. 6, pp. 623-633 . https://doi.org/10.1080/1061186X.2022.2036164
Endometrial cancer (EC) is a common and deadly cancer in women and novel therapeutic approaches are urgently needed. Polyamines (putrescine, spermidine, spermine) are critical for mammalian cell proliferation and MYC coordinately regulates polyamine
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01fcf43aaa482551b02014fe14b57f98
https://research.vumc.nl/en/publications/bbf01a78-9965-47bd-b9ba-947cec7834ee
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5
Akademický článek
Gene expression in uterine leiomyoma from tumors likely to be growing (from black women over 35) and tumors likely to be non-growing (from white women over 35).
Autor: Barbara J Davis, John I Risinger, Gadisetti V R Chandramouli, Pierre R Bushel, Donna Day Baird, Shyamal D Peddada
Publikováno v: PLoS ONE, Vol 8, Iss 6, p e63909 (2013)
The study of uterine leiomyomata (fibroids) provides a unique opportunity to investigate the physiological and molecular determinants of hormone dependent tumor growth and spontaneous tumor regression. We conducted a longitudinal clinical study of pr
Externí odkaz: https://doaj.org/article/d8e4073e46a445559a6fba9cc0ee0715
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6
Evaluation of partial k-space strategies to speed up time-domain EPR imaging
Autor: Sankaran, Subramanian, Gadisetti V R, Chandramouli, Alan, McMillan, Rao P, Gullapalli, Nallathamby, Devasahayam, James B, Mitchell, Shingo, Matsumoto, Murali C, Krishna
Publikováno v: Magnetic resonance in medicine. 70(3)
Narrow-line spin probes derived from the trityl radical have led to the development of fast in vivo time-domain EPR imaging. Pure phase-encoding imaging modalities based on the single-point imaging scheme have demonstrated the feasibility of three-di
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b75728e24c65da3403d6ec4c607fdca9
https://pubmed.ncbi.nlm.nih.gov/23045171
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7
Dose-dependent effects of calorie restriction on gene expression, metabolism, and tumor progression are partially mediated by insulin-like growth factor-1
Autor: Huaitian Lui, Gadisetti V R Chandramouli, Leticia Nogueira, Jackie A. Lavigne, Stephen D. Hursting, J. Carl Barrett
Publikováno v: Cancer Medicine
The prevalence of obesity, an established risk and progression factor for breast and many other cancer types, remains very high in the United States and throughout the world. Calorie restriction (CR), a reduced-calorie dietary regimen typically invol
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de14dd64a25b92e0fff85d19b2733398
https://pubmed.ncbi.nlm.nih.gov/23342276
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8
The in vitro and in vivo effects of re-expressing methylated von Hippel-Lindau tumor suppressor gene in clear cell renal carcinoma with 5-aza-2'-deoxycytidine
Autor: Wade G, Alleman, Ray L, Tabios, Gadisetti V R, Chandramouli, Olga N, Aprelikova, Carlos, Torres-Cabala, Arnulfo, Mendoza, Craig, Rogers, Craig, Rodgers, Nikolai A, Sopko, W Marston, Linehan, James R, Vasselli
Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 10(20)
Clear cell renal carcinoma (ccRCC) is strongly associated with loss of the von Hippel-Lindau (VHL) tumor suppressor gene. The VHL gene is functionally lost through hypermethylation in up to 19% of sporadic ccRCC cases. We theorized that re-expressing
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b389005f1d287852c1aa139828d94fb4
https://pubmed.ncbi.nlm.nih.gov/15501981
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9
Global expression profiling identifies signatures of tumor virulence in MMTV-PyMT-transgenic mice: correlation to human disease
Autor: Ting Hu, Qiu, Gadisetti V R, Chandramouli, Kent W, Hunter, Nawal W, Alkharouf, Jeffrey E, Green, Edison T, Liu
Publikováno v: Cancer research. 64(17)
FVB/N-Tg (MMTV-PyMT)(634Mul)-transgenic mice develop multifocal mammary tumors with a high incidence of pulmonary metastasis. We have demonstrated previously that mammary tumors derived from transgene-positive F1 progeny in particular inbred strains
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::91d565ac7b07b084f77995029a2d4d6f
https://pubmed.ncbi.nlm.nih.gov/15342376
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