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Two decades of molecular surveillance in Senegal reveal changes in known drug resistance mutations associated with historical drug use and seasonal malaria chemoprevention.

Autor: Ndiaye YD; International Research Training Center on Genomics and Health Surveillance (CIGASS), Cheikh Anta Diop University, Dakar, 16477, Senegal., Wong W; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, 665 Huntington Ave, Boston, MA, 02115, USA., Thwing J; Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA ,30329, USA., Schaffner SS; Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA, 02142, USA., Tine A; International Research Training Center on Genomics and Health Surveillance (CIGASS), Cheikh Anta Diop University, Dakar, 16477, Senegal., Diallo MA; International Research Training Center on Genomics and Health Surveillance (CIGASS), Cheikh Anta Diop University, Dakar, 16477, Senegal., Deme A; International Research Training Center on Genomics and Health Surveillance (CIGASS), Cheikh Anta Diop University, Dakar, 16477, Senegal., Sy M; International Research Training Center on Genomics and Health Surveillance (CIGASS), Cheikh Anta Diop University, Dakar, 16477, Senegal., Bei AK; Yale School of Public Health, 60 College St, New Haven, CT 06510., Thiaw AB; Department of biochemistry and Functional Genomics, Sherbrooke University, 2500 Bd de l'Universite, Sherbrooke, QC J1K 2R1, Canada., Daniels R; RNA Therapeutics Institute, UMass Chan Medical School, 368 Plantation Street, Worcester MA 01605., Ndiaye T; International Research Training Center on Genomics and Health Surveillance (CIGASS), Cheikh Anta Diop University, Dakar, 16477, Senegal., Gaye A; International Research Training Center on Genomics and Health Surveillance (CIGASS), Cheikh Anta Diop University, Dakar, 16477, Senegal., Ndiaye IM; International Research Training Center on Genomics and Health Surveillance (CIGASS), Cheikh Anta Diop University, Dakar, 16477, Senegal., Toure M; International Research Training Center on Genomics and Health Surveillance (CIGASS), Cheikh Anta Diop University, Dakar, 16477, Senegal., Gadiaga N; International Research Training Center on Genomics and Health Surveillance (CIGASS), Cheikh Anta Diop University, Dakar, 16477, Senegal., Sene A; International Research Training Center on Genomics and Health Surveillance (CIGASS), Cheikh Anta Diop University, Dakar, 16477, Senegal., Sow D; International Research Training Center on Genomics and Health Surveillance (CIGASS), Cheikh Anta Diop University, Dakar, 16477, Senegal., Garba MN; International Research Training Center on Genomics and Health Surveillance (CIGASS), Cheikh Anta Diop University, Dakar, 16477, Senegal., Yade MS; International Research Training Center on Genomics and Health Surveillance (CIGASS), Cheikh Anta Diop University, Dakar, 16477, Senegal., Dieye B; International Research Training Center on Genomics and Health Surveillance (CIGASS), Cheikh Anta Diop University, Dakar, 16477, Senegal., Diongue K; International Research Training Center on Genomics and Health Surveillance (CIGASS), Cheikh Anta Diop University, Dakar, 16477, Senegal., Zoumarou D; International Research Training Center on Genomics and Health Surveillance (CIGASS), Cheikh Anta Diop University, Dakar, 16477, Senegal., Ndiaye A; International Research Training Center on Genomics and Health Surveillance (CIGASS), Cheikh Anta Diop University, Dakar, 16477, Senegal., Gomis J; International Research Training Center on Genomics and Health Surveillance (CIGASS), Cheikh Anta Diop University, Dakar, 16477, Senegal., Fall FB; Yale School of Public Health, 60 College St, New Haven, CT 06510., Ndiop M; National Malaria Control Program (NMCP), Rue FN 20, Dakar 25270, Senegal., Diallo I; National Malaria Control Program (NMCP), Rue FN 20, Dakar 25270, Senegal., Sene D; National Malaria Control Program (NMCP), Rue FN 20, Dakar 25270, Senegal., Macinnis B; Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA, 02142, USA., Seck MC; International Research Training Center on Genomics and Health Surveillance (CIGASS), Cheikh Anta Diop University, Dakar, 16477, Senegal., Ndiaye M; International Research Training Center on Genomics and Health Surveillance (CIGASS), Cheikh Anta Diop University, Dakar, 16477, Senegal., Badiane AS; International Research Training Center on Genomics and Health Surveillance (CIGASS), Cheikh Anta Diop University, Dakar, 16477, Senegal., Hartl DL; Department of Organismic and Evolutionary Biology, Harvard University, 16 Divinity Avenue, Cambridge, MA, 02138 USA., Volkman SK; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, 665 Huntington Ave, Boston, MA, 02115, USA.; Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA, 02142, USA.; Simmons University, 300 The Fenway, Boston, MA, 02115, USA., Wirth DF; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, 665 Huntington Ave, Boston, MA, 02115, USA.; Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA, 02142, USA., Ndiaye D; International Research Training Center on Genomics and Health Surveillance (CIGASS), Cheikh Anta Diop University, Dakar, 16477, Senegal.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, 665 Huntington Ave, Boston, MA, 02115, USA.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2023 Apr 26. Date of Electronic Publication: 2023 Apr 26.