Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Gadi Turgeman"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Although the effects of paternal exposure to insults on the offspring received limited attention in the past, it is currently gaining interest especially after understanding the mechanisms which may mediate such exposure effects. In the curr
Externí odkaz:
https://doaj.org/article/76bab92e56dc4be7a233bf9457e6d424
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 432 (2023)
Among the proposed mechanisms for autism spectrum disorders (ASD) is immune dysregulation. The proinflammatory cytokine Interleukine-17A (IL-17A) was shown to play a key role in mediating immune-related neurodevelopmental impairment of social behavio
Externí odkaz:
https://doaj.org/article/1aa82f2f0d084a52885c575a8f2f0834
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 5047 (2023)
Parental exposure to insults was initially considered safe if stopped before conception. In the present investigation, paternal or maternal preconception exposure to the neuroteratogen chlorpyrifos was investigated in a well-controlled avian model (F
Externí odkaz:
https://doaj.org/article/941bc09b65a64f7db5a7ae3d4c24fe27
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4490 (2023)
Age-related decline in cognitive functions is associated with reduced hippocampal neurogenesis caused by changes in the systemic inflammatory milieu. Mesenchymal stem cells (MSC) are known for their immunomodulatory properties. Accordingly, MSC are a
Externí odkaz:
https://doaj.org/article/60d8103d98704ee087273dd9b280fd32
Autor:
Yehoshua Willinger, Gadi Turgeman
Publikováno v:
Cells, Vol 11, Iss 3, p 343 (2022)
Post-traumatic stress disorder (PTSD) is a psychiatric disorder accompanied by deficits in cognitive and social skills. Adult hippocampal neurogenesis is a lifelong phenomenon, with new neurons being formed in the granular cell layer of the dentate g
Externí odkaz:
https://doaj.org/article/e79370978bee40b7bf27d5348788d2a8
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 21, p 5278 (2019)
In previous studies we produced autism like behavioral changes in mice by Valproic acid (VPA) with significant differences between genders. S-adenosine methionine (SAM) prevented the autism like behavior in both genders. The expression of 770 genes o
Externí odkaz:
https://doaj.org/article/90ee48e126484457b71cb1df18e14d36
Autor:
Gadi Turgeman
Publikováno v:
Neural Regeneration Research, Vol 10, Iss 5, Pp 698-699 (2015)
Externí odkaz:
https://doaj.org/article/1a7101bd9cd34ce8976c3a01774f3d0d
Publikováno v:
Molecular Psychiatry. 26:4448-4463
Schizophrenia is a neurodevelopmental disease with a mixed genetic and environmental aetiology. Impaired adult hippocampal neurogenesis was suggested both as a pathophysiological mechanism and as a target for therapy. In the present study, we utilize
Autor:
Gadi Turgeman, Issam Rimawi, Eliyahu M. Heifetz, Adi Pinkas, Dana Pulver, Itamar Altman, Joseph Yanai
Publikováno v:
Neurotoxicology and teratology. 90
Neurobehavioral teratology is the study of typically subtle neurobehavioral birth defects. Our previously described mouse model demonstrated septohippocampal cholinergic innervation-related molecular and behavioral deficits after prenatal exposure to
Autor:
Gadi Turgeman, Matanel Tfilin
Publikováno v:
Journal of Molecular Neuroscience. 69:254-263
Adult hippocampal neurogenesis plays an important role in health and disease. Regulating neurogenesis may be a key mechanism in the pathophysiology and treatment of several neurobehavioral disorders such as schizophrenia, depression, autism spectrum