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pro vyhledávání: '"Gade Balaji"'
Autor:
V.J. Sebastian, Sanjita Sasmal, Rashmi Talwar, Pradip Kumar Sasmal, Hariprasada R. Kanna Reddy, Gujjary Srinivas, D. Balasubrahmanyam, ShivaKumar Kyasa, K. Harinder Reddy, Gade Balaji, Ish Kumar Khanna, Syed Muzeeb, Jerad Suresh, Øystein Rist, Thomas Högberg, Lisbeth Elster, Dhanya Shashikumar, Thomas M. Frimurer, Vikram P. Jadhav
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:3157-3162
Melanin concentrating hormone (MCH) is an important mediator of energy homeostasis and plays a role in metabolic and CNS disorders. The modeling-supported design, synthesis and multi-parameter optimization (biological activity, solubility, metabolic