Zobrazeno 1 - 10
of 769
pro vyhledávání: '"Gadd45a"'
Autor:
Dan Du, Mingxia Zhou, Chenxi Ju, Jie Yin, Chang Wang, Xinyu Xu, Yunqing Yang, Yun Li, Le Cui, Zhengyang Wang, Yuqing Lei, Hongle Li, Fucheng He, Jing He
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-18 (2024)
Abstract Background RNA modifications of transfer RNAs (tRNAs) are critical for tRNA function. Growing evidence has revealed that tRNA modifications are related to various disease processes, including malignant tumors. However, the biological functio
Externí odkaz:
https://doaj.org/article/2952b19721fd42eeae5d67470604132e
Autor:
Shitao Wang, Zhenrong Xie, Tian Jun, Xuelu Ma, Mengen Zhang, Feng Rao, Hui Xu, Jinghong Lu, Xiangqian Ding, Zongyou Li
Publikováno v:
European Journal of Medical Research, Vol 29, Iss 1, Pp 1-7 (2024)
Abstract Background Epilepsy, a central neurological disorder, has a complex genetic architecture. There is some evidence suggesting that genetic factors play a role in both the occurrence of epilepsy and its treatment. However, the genetic determina
Externí odkaz:
https://doaj.org/article/bf4799d276434c9186c5dfc5627b0bfd
Publikováno v:
Open Medicine, Vol 18, Iss 1, Pp 835750-54 (2023)
Lung epithelial cells and fibroblasts poorly express angiotensin-converting enzyme 2, and the study aimed to investigate the role of the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on inflammation and epithelial–me
Externí odkaz:
https://doaj.org/article/0a26888eb22f45e7b8cbeae489c6c0d5
Autor:
Yuhang Hou, Hongyun Hao, Yan Yuan, Jing Zhang, Zhengrui Liu, Yimin Nie, Shichang Zhang, Shengtao Yuan, Mei Yang
Publikováno v:
Pharmaceuticals, Vol 17, Iss 10, p 1269 (2024)
(1) Background: Nifuratel (NF113), derived from nitrofuran, has a specific anti-tumor effect. However, the potential mechanisms of NF113 in triple-negative breast cancer remain unknown. (2) Methods: In the study, CCK8 assay and colony formation assay
Externí odkaz:
https://doaj.org/article/55feb1c1705d4df2b55a55a55a38a190
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Obesity, characterized by excessive white adipose tissue expansion, is associated with several metabolic complications. Identifying new adipogenesis regulators may lead to effective therapies for obesity-induced metabolic disorder
Externí odkaz:
https://doaj.org/article/0f32e860f7244d38a558d6032dd2913b
Publikováno v:
Journal of Obstetrics and Gynaecology, Vol 43, Iss 2 (2023)
AbstractObjective Tanshinol is an active constituent of Salvia miltiorrhiza that possesses anti-inflammatory, antioxidant, and antibacterial activities. Therefore, this study attempted to detect whether it has a role in the treatment of preeclampsia
Externí odkaz:
https://doaj.org/article/d142886b45b74351a4107d58d5423a57
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Purpose To evaluate the anticancer activities of lenvatinib in ICC and its possible molecular mechanisms. Methods Patients-derived xenograft (PDX) model and cell line-derived xenograft (CDX) model were both used for the in vivo study. For in
Externí odkaz:
https://doaj.org/article/439ea212fb39440193dfe56c87ce6cb4
Autor:
Wenjing You, Shiqi Liu, Jianfei Ji, Defeng Ling, Yuang Tu, Yanbing Zhou, Wentao Chen, Teresa G. Valencak, Yizhen Wang, Tizhong Shan
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 1, Pp 326-341 (2023)
Abstract Background Skeletal muscle fat infiltration is a common feature during ageing, obesity and several myopathies associated with muscular dysfunction and sarcopenia. However, the regulatory mechanisms of intramuscular adipogenesis and strategie
Externí odkaz:
https://doaj.org/article/e9d83c933131464ea3ecee11dfb064d4
Autor:
Lu-Rong Yu, Xian-Zhong Han, Ying-Zi Tang, Dan Liu, Xian-Qin Luo, Xue-Wen Qiu, Jie Feng, Wen-Xiao Yuan, Jia-Yu Ding
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 4, p 160 (2024)
Background: Nasopharyngeal carcinoma (NPC) is a malignant tumor associated with Epstein-Barr virus (EBV) infection. Chemoradiotherapy is the mainstream treatment for locally advanced NPC, and chemotherapeutic drugs are an indispensable part of NPC tr
Externí odkaz:
https://doaj.org/article/9d6337a5951b449e9c2d8cfa9f7de52a
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