Rôle d'ADAR1 dans le développement de la crête neurale

Autor: Gacem, Nadjet

Les cellules de le crête neurale sont une population de cellules précurseurs multipotentes qui émergent aux frontières du tube neural et de l’ectoderme non neural, migrent de manière extensive dans tout l'embryon et se différencient en une va

Externí odkaz: http://www.theses.fr/2019PESC0016

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ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development

Autor: Gacem, Nadjet, Kavo, Anthula, Zerad, Lisa, Richard, Laurence, Mathis, Stephane, Kapur, Raj, Parisot, Mélanie, Amiel, Jeanne, de La Grange, Pierre, Pingault, Veronique, Vallat, Jean, Bondurand, Nadege, Dufour, Sylvie

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.198. ⟨10.1038/s41467-019-14090-5⟩
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications, 2020, 11 (1), pp.198. ⟨10.1038/s41467-019-14090-5⟩

The neural crest gives rise to numerous cell types, dysfunction of which contributes to many disorders. Here, we report that adenosine deaminase acting on RNA (ADAR1), responsible for adenosine-to-inosine editing of RNA, is required for regulating th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::859166586e80a1961ccdcb1605eb2782
https://www.hal.inserm.fr/inserm-02494188

ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development.

Autor: Gacem N; Laboratory of Embryology and Genetics of Human Malformation, Imagine Institute, INSERM UMR 1163, Universite Paris Descartes-Universite de Paris, Paris, France.; INSERM, U955, Equipe 06, 8, rue du General Sarrail, 94010, Creteil Cedex, France., Kavo A; INSERM, U955, Equipe 06, 8, rue du General Sarrail, 94010, Creteil Cedex, France.; Faculte de Medecine, Universite Paris Est, 94000, Creteil, France., Zerad L; Laboratory of Embryology and Genetics of Human Malformation, Imagine Institute, INSERM UMR 1163, Universite Paris Descartes-Universite de Paris, Paris, France., Richard L; Department of Neurology, Centre de Reference Neuropathies Peripheriques Rares, 2 avenue Martin-Luther-King, 87042, Limoges, France., Mathis S; Department of Neurology (Nerve-Muscle Unit) and Grand Sud-Ouest National Reference Center for Neuromuscular Disorders, CHU Bordeaux, Pellegrin Hospital, 33076, Bordeaux, France., Kapur RP; Department of Pathology, Seattle Children's Hospital and University of Washington, 4800 Sand Point Way NE, Seattle, WA, 98105, USA., Parisot M; Genomics Core Facility, Institut Imagine-Structure Federative de Recherche Necker, INSERM U1163 and INSERM US24/CNRS UMS3633, 24 bvd Montparnasse, 75015, Paris, France., Amiel J; Laboratory of Embryology and Genetics of Human Malformation, Imagine Institute, INSERM UMR 1163, Universite Paris Descartes-Universite de Paris, Paris, France., Dufour S; INSERM, U955, Equipe 06, 8, rue du General Sarrail, 94010, Creteil Cedex, France.; Faculte de Medecine, Universite Paris Est, 94000, Creteil, France., de la Grange P; GenoSplice, Paris, France., Pingault V; Laboratory of Embryology and Genetics of Human Malformation, Imagine Institute, INSERM UMR 1163, Universite Paris Descartes-Universite de Paris, Paris, France.; Service de Genetique Moleculaire, Hopital Necker-Enfants-Malades, 149 rue de Sevres, 75015, Paris, France., Vallat JM; Department of Neurology, Centre de Reference Neuropathies Peripheriques Rares, 2 avenue Martin-Luther-King, 87042, Limoges, France., Bondurand N; Laboratory of Embryology and Genetics of Human Malformation, Imagine Institute, INSERM UMR 1163, Universite Paris Descartes-Universite de Paris, Paris, France. nadege.bondurand@inserm.fr.; INSERM, U955, Equipe 06, 8, rue du General Sarrail, 94010, Creteil Cedex, France. nadege.bondurand@inserm.fr.

Publikováno v: Nature communications [Nat Commun] 2020 Jan 10; Vol. 11 (1), pp. 198. Date of Electronic Publication: 2020 Jan 10.