Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Gaby S. Brouns"'
Publikováno v:
Immunogenetics. 48:305-311
B-cell commitment is characterized by the expression of specific membrane proteins and the rearrangement and expression of immunoglobulin (Ig) heavy (H) and light (L) chain genes. At early stages of B-cell development, unrearranged Ig loci are transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c86cbb9e775e48943ba0f730f06e077a
https://doi.org/10.1007/s002510050437
https://doi.org/10.1007/s002510050437
Publikováno v:
International Immunology. 7:359-368
The B cell antigen receptor (BCR) complex consists of transmembrane (m) Ig, in non-covalent association with a disulphide-linked heterodimer of mb-1 and B29 gene products. The MB-1-B29 heterodimer is required for deposition of the BCR at the plasma m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::448108d86958958ee498d1db882c0e6f
https://doi.org/10.1093/intimm/7.3.359
https://doi.org/10.1093/intimm/7.3.359
Autor:
Ruud K. B. Schuurman, Rudolf W. Hendriks, Gaby S. Brouns, Christine Kinnon, Jannie Borst, S. Hinshelwood, M. De Weers
Publikováno v:
Journal of Biological Chemistry. 269:23857-23860
X-linked agammaglobulinemia (XLA) is an inherited human immunodeficiency disease, characterized by an arrest in B-cell development, which results in a dramatic decrease in immunoglobulin production. The gene product defective in XLA has been identifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::716294953e837619f9c1e616182b70f4
https://doi.org/10.1016/s0021-9258(19)51014-6
https://doi.org/10.1016/s0021-9258(19)51014-6
Autor:
M. C. M. Verschuren, David Y. Mason, Evert de Vries, Jacques J.M. van Dongen, Gaby S. Brouns, Jannie Borst
Publikováno v:
Scopus-Elsevier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f74f5289224a6e3f6fbdbf2fc8bec3a9
https://doi.org/10.1111/j.1600-065x.1993.tb00837.x
https://doi.org/10.1111/j.1600-065x.1993.tb00837.x
Autor:
Ruth C. Lovering, Rob G.J. Mensink, Gaby S. Brouns, M. De Weers, Ruud K. B. Schuurman, Margriet E. M. Kraakman, Rudolf W. Hendriks, Jannie Borst, G. M. Dingjan
Publikováno v:
Clinical and experimental immunology. 107(2)
SUMMARY X-linked agammaglobulinaemia (XLA) is an immunodeficiency caused by mutations in Bruton's tyrosine kinase (Btk) and is characterized by an almost complete arrest of B cell development. We analysed expression of Btk in B lymphoblastoid cell li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd6569f889b51c140ca0b7fb9ee685e5
https://pubmed.ncbi.nlm.nih.gov/9030858
https://pubmed.ncbi.nlm.nih.gov/9030858
Publikováno v:
The Journal of biological chemistry. 271(32)
The pre-B cell receptor (BCR) complex, consisting of micro heavy chain, a pseudo-light chain, and the Mb-1/B29 heterodimer, directs the transition to the mature B cell stage. Plasma membrane expression of the pre-BCR is extremely low, despite its pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::899ba036eba0ba2f85553cd6d376dc6a
https://pubmed.ncbi.nlm.nih.gov/8702609
https://pubmed.ncbi.nlm.nih.gov/8702609
Publikováno v:
Current opinion in immunology. 8(2)
The precursor T-cell receptors (TCRs) and B-cell receptors (BCRs) direct lymphocyte development to the mature T-cell and B-cell stage, respectively. Recent genetic and biochemical experiments reveal the striking parallel in structure and function of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2b0f09854a617842b021c93b085c931
https://pubmed.ncbi.nlm.nih.gov/8725941
https://pubmed.ncbi.nlm.nih.gov/8725941