Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Gabsang Lee"'
Autor:
Hyerin Choi, Dongjin Oh, Mirae Kim, Ali Jawad, Haomiao Zheng, Lian Cai, Joohyeong Lee, Eunhye Kim, Gabsang Lee, Hyewon Jang, Changjong Moon, Sang-Hwan Hyun
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Background The establishment of stable porcine embryonic stem cells (pESCs) can contribute to basic and biomedical research, including comparative developmental biology, as well as assessing the safety of stem cell-based therapies. Despite t
Externí odkaz:
https://doaj.org/article/02c1d1fd4f8b44bf9a4a21eb99a277fd
Autor:
Kathryn R. Moss, Ruifa Mi, Riki Kawaguchi, Jeffrey T. Ehmsen, Qiang Shi, Paula I. Vargas, Bipasha Mukherjee-Clavin, Gabsang Lee, Ahmet Höke
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109855- (2024)
Summary: Establishing robust models of human myelinating Schwann cells is critical for studying peripheral nerve injury and disease. Stem cell differentiation has emerged as a key human cell model and disease motivating development of Schwann cell di
Externí odkaz:
https://doaj.org/article/389891808e4c4e01a9bfaa5738861059
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102609- (2023)
Summary: Alpha-synuclein (α-syn) aggregation is a principal factor in Parkinson’s disease (PD) onset. Here, we present a protocol for optogenetic induction of α-syn aggregation in human midbrain dopaminergic (mDA) neurons, facilitating a detailed
Externí odkaz:
https://doaj.org/article/7269bb2140764db29ebc4465e07c5235
Autor:
Dongjin Oh, Hyerin Choi, Mirae Kim, Lian Cai, Joohyeong Lee, Ali Jawad, Sohee Kim, Haomiao Zheng, Gabsang Lee, Yubyeol Jeon, Sang-Hwan Hyun
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Interleukin-7 (IL-7), a vital factor that affects cell development, proliferation, and survival, plays an important role in oocyte maturation. However, its role in embryonic development remains unknown. Therefore, in this study, we aimed to investiga
Externí odkaz:
https://doaj.org/article/e62055801bd546d1bb90c601468f8eff
Autor:
Hyerin Choi, Dongjin Oh, Mirae Kim, Lian Cai, Joohyeong Lee, Eunhye Kim, Gabsang Lee, Sang-Hwan Hyun
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The trace element Cu is required for the activity of various enzymes essential for physiological processes. In this study, we elucidated the copper transport system in porcine follicular cells and investigated the effect of Cu chelation during in vit
Externí odkaz:
https://doaj.org/article/52617413bbc04c01bc756e68741d675d
Autor:
Mirae Kim, Seon-Ung Hwang, Junchul David Yoon, Joohyeong Lee, Eunhye Kim, Lian Cai, Hyerin Choi, Dongjin Oh, Gabsang Lee, Sang-Hwan Hyun
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Neurotrophin-4 (NT-4), a granulosa cell-derived factor and a member of the neurotrophin family, is known to promote follicular development and oocyte maturation in mammals. However, the physiological and functional roles of NT-4 in porcine ovarian de
Externí odkaz:
https://doaj.org/article/943a838b2b504558bf789a9845f33959
Autor:
Yang Zhang, Xiang Xu, Yuxin Tong, Xijie Zhou, Jian Du, In Young Choi, Shouwei Yue, Gabsang Lee, Blake N. Johnson, Xiaofeng Jia
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-11 (2021)
Abstract Background Severe peripheral nerve injury significantly affects patients’ quality of life and induces neuropathic pain. Neural crest stem cells (NCSCs) exhibit several attractive characteristics for cell-based therapies following periphera
Externí odkaz:
https://doaj.org/article/c694c5e5f1e3444cb59073bffef239d0
Autor:
Arens Taga, Raha Dastgheyb, Christa Habela, Jessica Joseph, Jean‐Philippe Richard, Sarah K. Gross, Giuseppe Lauria, Gabsang Lee, Norman Haughey, Nicholas J. Maragakis
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 12, Pp 1272-1285 (2019)
Abstract The ability to generate human‐induced pluripotent stem cell (hiPSC)‐derived neural cells displaying region‐specific phenotypes is of particular interest for modeling central nervous system biology in vitro. We describe a unique method
Externí odkaz:
https://doaj.org/article/90f3a373826542afa217b6c5c8f992af
Autor:
Sarah M. Somers, Jordana Gilbert-Honick, In Young Choi, Emily K. W. Lo, HoTae Lim, Shaquielle Dias, Kathryn R. Wagner, Hai-Quan Mao, Patrick Cahan, Gabsang Lee, Warren L. Grayson
Publikováno v:
Bioengineering, Vol 9, Iss 11, p 693 (2022)
Tissue engineering strategies that combine human pluripotent stem cell-derived myogenic progenitors (hPDMs) with advanced biomaterials provide promising tools for engineering 3D skeletal muscle grafts to model tissue development in vitro and promote
Externí odkaz:
https://doaj.org/article/a6b89d7824424fbe817383c8b7bdca00
Autor:
In Young Choi, Hotae Lim, Hyeon Jin Cho, Yohan Oh, Bin-Kuan Chou, Hao Bai, Linzhao Cheng, Yong Jun Kim, SangHwan Hyun, Hyesoo Kim, Joo Heon Shin, Gabsang Lee
Publikováno v:
eLife, Vol 9 (2020)
Generation of skeletal muscle cells with human pluripotent stem cells (hPSCs) opens new avenues for deciphering essential, but poorly understood aspects of transcriptional regulation in human myogenic specification. In this study, we characterized th
Externí odkaz:
https://doaj.org/article/2ec2845de8084974b69d4de181793812