Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Gabrielle Smith"'
Autor:
Emily Warmington, Gabrielle Smith, Vasileios Chortis, Raimunde Liang, Juliane Lippert, Sonja Steinhauer, Laura-Sophie Landwehr, Constanze Hantel, Katja Kiseljak-Vassiliades, Margaret E Wierman, Barbara Altieri, Paul A Foster, Cristina L Ronchi
Publikováno v:
Endocrine Connections, Vol 13, Iss 1, Pp 1-12 (2023)
Adrenocortical carcinoma (ACC) is an aggressive malignancy with limited treatment options. Polo-like kinase 1 (PLK1) is a promising drug target; PLK1 inhibitors (PLK1i) have been investigated in solid cancers and are more effective in TP53-mutated ca
Externí odkaz:
https://doaj.org/article/e4efec62f5f64d8ab3df24cff09f9c14
Autor:
Daniela Nasteska, Nicholas H. F. Fine, Fiona B. Ashford, Federica Cuozzo, Katrina Viloria, Gabrielle Smith, Aisha Dahir, Peter W. J. Dawson, Yu-Chiang Lai, Aimée Bastidas-Ponce, Mostafa Bakhti, Guy A. Rutter, Remi Fiancette, Rita Nano, Lorenzo Piemonti, Heiko Lickert, Qiao Zhou, Ildem Akerman, David J. Hodson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Beta cell subpopulations with low expression in PDX1, MAFA, and insulin might contribute to islet function and insulin release. Here the authors show that altering the proportion of PDX1LOW MAFALOW to PDX1HIGH MAFAHIGH cells impairs islet function.
Externí odkaz:
https://doaj.org/article/cf504598ffd644018cbb1c9c1fc2bf2c
Autor:
Ildem Akerman, Bahar Kasaai, Alina Bazarova, Pau Biak Sang, Isabelle Peiffer, Marie Artufel, Romain Derelle, Gabrielle Smith, Marta Rodriguez-Martinez, Manuela Romano, Sandrina Kinet, Peter Tino, Charles Theillet, Naomi Taylor, Benoit Ballester, Marcel Méchali
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
In metazoan the DNA sequence elements characterizing origin specification are unknown. By generating and analysing 19 SNS-seq datasets from different human cell types, the authors reveal a class and features of Core origins of replication which can b
Externí odkaz:
https://doaj.org/article/9fd4abfa0458400da994ba8ead8f7cae
Autor:
Connar S.J. Westgate, Hannah F. Botfield, Zerin Alimajstorovic, Andreas Yiangou, Mark Walsh, Gabrielle Smith, Rishi Singhal, James L. Mitchell, Olivia Grech, Keira A. Markey, Daniel Hebenstreit, Daniel A. Tennant, Jeremy W. Tomlinson, Susan P. Mollan, Christian Ludwig, Ildem Akerman, Gareth G. Lavery, Alexandra J. Sinclair
Publikováno v:
JCI Insight, Vol 6, Iss 10 (2021)
BACKGROUND Idiopathic intracranial hypertension (IIH) is a condition predominantly affecting obese women of reproductive age. Recent evidence suggests that IIH is a disease of metabolic dysregulation, androgen excess, and an increased risk of cardiov
Externí odkaz:
https://doaj.org/article/ad869628076c4e20ba99df429a35f377
Autor:
Daniela Nasteska, Nicholas H. F. Fine, Fiona B. Ashford, Federica Cuozzo, Katrina Viloria, Gabrielle Smith, Aisha Dahir, Peter W. J. Dawson, Yu-Chiang Lai, Aimée Bastidas-Ponce, Mostafa Bakhti, Guy A. Rutter, Remi Fiancette, Rita Nano, Lorenzo Piemonti, Heiko Lickert, Qiao Zhou, Ildem Akerman, David J. Hodson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/babcfb71b6f54a778b28993243b49eed
Autor:
Gabrielle Smith
Publikováno v:
Critique. :480-494
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::286b61600a3e03a8e23c25721814ad88
https://doi.org/10.3917/criti.901.0480
https://doi.org/10.3917/criti.901.0480
Autor:
Christina H. Moon, Gabrielle Smith
Publikováno v:
Critique. :461-471
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c37e03dd0010743d6625f4c21033b63
https://doi.org/10.3917/criti.901.0461
https://doi.org/10.3917/criti.901.0461
Autor:
Juliane Lippert, Barbara Altieri, Breanna Morrison, Sonja Steinhauer, Gabrielle Smith, Antonia Lorey, Hanna Urlaub, Stefan Kircher, Alice Sitch, Martin Fassnacht, Cristina L Ronchi
Publikováno v:
The Journal of clinical endocrinology and metabolism. 107(10)
Context Adrenocortical carcinoma (ACC) is a rare aggressive disease with heterogeneous prognoses. Previous studies identified hypermethylation in the promoter region of specific genes to be associated with poor clinical outcome. Objective Comparative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe7893d6ae0b9bed8e49bcbc9802e6c9
https://pubmed.ncbi.nlm.nih.gov/35929659
https://pubmed.ncbi.nlm.nih.gov/35929659
Background: Current management recommendations for asymptomatic bacteriuria (ABU) in pregnancy is based primarily on expert opinion and requires further study. We examined the role of screening urine cultures and “test of cure” urine cultures (TO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7988a4e5cdad78f7b70704b002e793f2
https://doi.org/10.21203/rs.3.rs-1667326/v1
https://doi.org/10.21203/rs.3.rs-1667326/v1
Autor:
Gabrielle Smith
Publikováno v:
The Graduate Inequality Review. 1
Wastewater management is difficult and expensive at the best of times but is particularly challenging under harsh Arctic conditions. In Nunavut, wastewater is treated via waste stabilisation ponds because of their relatively low capital and operation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2962f4b4bef47d095da70c1b4c40748c
https://doi.org/10.56298/h3fafkngms
https://doi.org/10.56298/h3fafkngms