Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Gabrielle S. Tender"'
Autor:
Alice J. Michel, Lewis M. Ward, Shana K. Goffredi, Katherine S. Dawson, Daniel T. Baldassarre, Alec Brenner, Kiyoko M. Gotanda, John E. McCormack, Sean W. Mullin, Ariel O’Neill, Gabrielle S. Tender, J. Albert C. Uy, Kristie Yu, Victoria J. Orphan, Jaime A. Chaves
Publikováno v:
Microbiome, Vol 6, Iss 1, Pp 1-14 (2018)
Abstract Background Darwin’s finches are a clade of 19 species of passerine birds native to the Galápagos Islands, whose biogeography, specialized beak morphologies, and dietary choices—ranging from seeds to blood—make them a classic example o
Externí odkaz:
https://doaj.org/article/516aa3d615b343728612103f48022f0b
Autor:
Kayvon Pedram, D. Judy Shon, Gabrielle S. Tender, Natalia R. Mantuano, Jason J. Northey, Kevin J. Metcalf, Simon P. Wisnovsky, Nicholas M. Riley, Giovanni C. Forcina, Stacy A. Malaker, Angel Kuo, Benson M. George, Caitlyn L. Miller, Kerriann M. Casey, José G. Vilches-Moure, Valerie M. Weaver, Heinz Laübli, Carolyn R. Bertozzi
Targeted protein degradation is an emerging strategy for the elimination of classically undruggable proteins. Here, to expand the landscape of substrates that can be selectively degraded, we designed degraders which are dependent on both peptide sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9eae7cde10003a5bd8961704a25b061e
https://doi.org/10.1101/2022.05.20.492748
https://doi.org/10.1101/2022.05.20.492748
Autor:
Christophe Marchand, Yves Pommier, Bradley R. Kossmann, Chunli Yan, Sophia Lopez, Monica Abdelmalak, Gabrielle S. Tender, Ivaylo Ivanov
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:3232-3236
Tyrosyl-DNA phosphodiesterase 2 (TDP2) processes protein/DNA adducts resulting from abortive DNA topoisomerase II (Top2) activity. TDP2 inhibition could provide synergism with the Top2 poison class of chemotherapeutics. By virtual screening of the NC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e06ce5a26131458b3cd1e4cc2663de3
https://doi.org/10.1016/j.bmcl.2016.05.065
https://doi.org/10.1016/j.bmcl.2016.05.065
Autor:
Mark Cushman, Monica Abdelmalak, Gabrielle S. Tender, Christophe Marchand, P. V. Narasimha Reddy, Yves Pommier, Keli Agama, Daniel E. Beck, Sophia Lopez, Wei Lv
Publikováno v:
Journal of Medicinal Chemistry. 59:3840-3853
Several indenoisoquinolines have shown promise as anticancer agents in clinical trials. Incorporation of a nitrogen atom into the indenoisoquinoline scaffold offers the possibility of favorably modulating ligand-binding site interactions, physicochem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f34b412fcbcb155b7212ee37b997258
https://doi.org/10.1021/acs.jmedchem.6b00003
https://doi.org/10.1021/acs.jmedchem.6b00003
Autor:
Dagmar H. Leary, Baochuan Lin, Leonard M. Tender, Anthony P. Malanoski, Sarah M. Strycharz-Glaven, Gabrielle S. Tender, Brian J. Eddie, Zheng Wang, William Judson Hervey, Gary J. Vora
Publikováno v:
PROTEOMICS. 15:3486-3496
Microorganisms that respire electrodes may be exploited for biotechnology applications if key pathways for extracellular electron transfer can be identified and manipulated through bioengineering. To determine whether expression of proposed Biocathod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a085ccf4bd59128a88c763e659cd3f4
https://doi.org/10.1002/pmic.201400585
https://doi.org/10.1002/pmic.201400585
Autor:
Christophe Marchand, Yves Pommier, P. V. Narasimha Reddy, Gabrielle S. Tender, Monica Abdelmalak, Keli Agama, Mark Cushman, Elizaveta O’Neill, Wei Lv, Daniel E. Beck
Publikováno v:
J Med Chem
3-Nitroindenoisoquinoline human topoisomerase IB (Top1) poisons have potent antiproliferative effects on cancer cells. The undesirable nitro toxicophore could hypothetically be replaced by other functional groups that would retain the desired biologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eae306ea73beb33f1fa7e9fb76198d0
https://doi.org/10.1021/acs.jmedchem.5b00303
https://doi.org/10.1021/acs.jmedchem.5b00303
Publikováno v:
eNeuro
A cation-π interaction between the ammonium group of an agonist and a conserved tryptophan termed TrpB is a near universal feature of agonist binding to nicotinic acetylcholine receptors (nAChRs). TrpB is one of five residues that form the aromatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6d158e37ecb1e634a3d5c0ca64374e3
https://resolver.caltech.edu/CaltechAUTHORS:20170612-100040551
https://resolver.caltech.edu/CaltechAUTHORS:20170612-100040551
Publikováno v:
Biophysical Journal. 110(3)
The Erwinia ligand-gated ion channel (ELIC) is a bacterial pentameric ligand ion channel (pLGIC) originally identified in the enterobacterium Erwinia chrysanthemii. ELIC is closely related to a large class of neurotransmitter-gated ion channels (Cys-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab873d2b2d604c5def2540f1dc83e6c
Autor:
Gary J. Vora, Leonard M. Tender, Robert W. Li, Sarah M. Strycharz-Glaven, Dagmar H. Leary, Baochuan Lin, Shelley G. Yanosky, Zheng Wang, Brian J. Eddie, Gabrielle S. Tender, W. Judson Hervey, Anthony P. Malanoski
Biocathode extracellular electron transfer (EET) may be exploited for biotechnology applications, including microbially mediated O 2 reduction in microbial fuel cells and microbial electrosynthesis. However, biocathode mechanistic studies needed to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4c661cebcb6928c1aca2028926bdb1d
https://resolver.caltech.edu/CaltechAUTHORS:20150206-102256272
https://resolver.caltech.edu/CaltechAUTHORS:20150206-102256272