Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Gabrielle R. Neises"'
Autor:
Richard L. Ornberg, Frances M. Platt, Philip G. Woodman, Terry D. Butters, Gabrielle R. Neises
Publikováno v:
Biology of the Cell. 89:123-131
The imino sugar N-butyldeoxynojirimycin inhibits the N-linked oligosaccharide processing enzymes α-glucosidases I and II, and the ceramide specific glucosyltransferase which catalyses the first step in glucosphingolipid biosynthesis. We have studied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f2263f93fbd2c21ca5666c1c8779a41
https://doi.org/10.1111/j.1768-322x.1997.tb01000.x
https://doi.org/10.1111/j.1768-322x.1997.tb01000.x
Autor:
Raymond A. Dwek, V H Perry, Frances M. Platt, T D Butters, Gabriele Reinkensmeier, M J Townsend, B Winchester, Richard L. Proia, Gabrielle R. Neises
Publikováno v:
Science. 276:428-431
The glycosphingolipid (GSL) lysosomal storage diseases result from the inheritance of defects in the genes encoding the enzymes required for catabolism of GSLs within lysosomes. A strategy for the treatment of these diseases, based on an inhibitor of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca501cba4e591536da1f4b41f4876761
https://doi.org/10.1126/science.276.5311.428
https://doi.org/10.1126/science.276.5311.428
Publikováno v:
Journal of Biological Chemistry. 269:27108-27114
We have previously reported that the imino sugar N-butyldeoxynojirimycin (NB-DNJ) inhibits glycolipid biosynthesis, in addition to its known activity as an inhibitor of the N-linked oligosaccharide processing enzyme alpha-glucosidase I. In an attempt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6d34ba0ac6794788b04b0fe5015b4ec
https://doi.org/10.1016/s0021-9258(18)47132-3
https://doi.org/10.1016/s0021-9258(18)47132-3
Publikováno v:
Journal of Biological Chemistry. 269:8362-8365
The imino sugar deoxynojirimycin and its alkylated derivatives are inhibitors of the N-linked oligosaccharide processing enzymes alpha-glucosidase I and II. These compounds are glucose analogues and have the potential to inhibit both glucosidases and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::340ecf50489fa54065b5095b28d0eb8f
https://doi.org/10.1016/s0021-9258(17)37202-2
https://doi.org/10.1016/s0021-9258(17)37202-2
Publikováno v:
The Anatomical Record. 205:57-63
Two morphological differences distinguish the membranes of the end bulb-spherical cell synapse in rats and mice from those in guinea pigs and chinchillas. First, in freeze-fracture replicas, the membranes of rat and mouse spherical cells lack perisyn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02ec35cfa9c17620592be3f653517e4b
https://doi.org/10.1002/ar.1092050108
https://doi.org/10.1002/ar.1092050108
Autor:
Jo-David Fine, Stephen M. Breathnach, Patricia A. Fox, Gabrielle R. Neises, John R. Stanley, Stephen I. Katz, Robert E. Jones
Publikováno v:
The American Journal of Dermatopathology. 7:171-180
Basic principles of production of monoclonal antibodies are discussed in this paper. In order to illustrate the usefulness of such production, studies of a new monoclonal antibody designated KF-2 which defines a unique cell-surface antigen found excl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c79b39f68a9823c747982b2da1970b6
https://doi.org/10.1097/00000372-198504000-00013
https://doi.org/10.1097/00000372-198504000-00013
Autor:
Patricia A. Fox, Gabrielle R. Neises, Stephen M. Breathnach, John R. Stanley, Stephen I. Katz
Publikováno v:
Journal of Investigative Dermatology. 80:392-395
The basement membrane zone (BMZ) of human skin is a complex structure which contains several well-defined components including bullous pemphigoid antigen, laminin, type IV collagen, and proteoglycan. Characterization of additional basement membrane (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9bc12ecee056a7344c4be865f2eaeb5
https://doi.org/10.1111/1523-1747.ep12553200
https://doi.org/10.1111/1523-1747.ep12553200
Publikováno v:
Journal of Investigative Dermatology. (1):39-43
We have studied various tissues from 10 patients with cicatricial pemphigoid using direct and indirect immunofluorescence, mechanical suction blister induction, and immunoelectron microscopy. In 8 of the 10 patients, direct immunofluorescence of bucc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9307b7cd78d6490fbabc7ba4c1e4d3ce
Publikováno v:
Journal of Investigative Dermatology. (2):108-113
In order to gain insight into the metabolism of keratin intermediate filaments (KIF) as well as the ability of KIF degradation products to interact with the immune system, we performed enzymatic degradation of purified KIF and examined their interact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::569a8657dcceb23661fdbfb6c02bcc7e
Publikováno v:
The Anatomical record. 204(3)
The freeze-fracture technique was used to study the maturation of the postsynaptic membrane of spherical cells of the anteroventral cochlear nucleus (AVCN) of the developing rat brain. Observations were made at 2-day intervals from birth to 16 days o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84444f5dd9c15b405555006db2e9f2da
https://pubmed.ncbi.nlm.nih.gov/7158832
https://pubmed.ncbi.nlm.nih.gov/7158832