Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Gabrielle Nickel"'
Autor:
Denis M. Tebit, Gabrielle Nickel, Richard Gibson, Myriam Rodriguez, Nicolas J. Hathaway, Katie Bain, Angel L. Reyes-Rodriguez, Pascal Ondoa, Jonathan L. Heeney, Yue Li, Jennifer Bongorno, David Canaday, David McDonald, Jeffrey A. Bailey, Eric J. Arts
Publikováno v:
EBioMedicine, Vol 100, Iss , Pp 104965- (2024)
Summary: Background: Simian immunodeficiency viruses (SIV) have been jumping between non-human primates in West/Central Africa for thousands of years and yet, the HIV-1 epidemic only originated from a primate lentivirus over 100 years ago. Methods: T
Externí odkaz:
https://doaj.org/article/2775faec513a4e519cd82b6bb90a918f
Autor:
Richard M. Gibson, Gabrielle Nickel, Michael Crawford, Fred Kyeyune, Colin Venner, Immaculate Nankya, Eva Nabulime, Emmanuel Ndashimye, Art F. Y. Poon, Robert A. Salata, Cissy Kityo, Peter Mugyenyi, Miguel E. Quiñones-Mateu, Eric J. Arts
Publikováno v:
Infectious Diseases of Poverty, Vol 6, Iss 1, Pp 1-13 (2017)
Abstract Background Thymidine analogs, namely AZT (Zidovudine or Retrovir™) and d4T (Stavudine or Zerit™) are antiretroviral drugs still employed in over 75% of first line combination antiretroviral therapy (cART) in Kampala, Uganda despite avers
Externí odkaz:
https://doaj.org/article/cc1b3016e85046149eaa13ef73e04de9
Autor:
Katja Klein, Gabrielle Nickel, Immaculate Nankya, Fred Kyeyune, Korey Demers, Emmanuel Ndashimye, Cynthia Kwok, Pai-Lien Chen, Sandra Rwambuya, Art Poon, Marshall Munjoma, Tsungai Chipato, Josaphat Byamugisha, Peter Mugyenyi, Robert A Salata, Charles S Morrison, Eric J Arts
Publikováno v:
PLoS Pathogens, Vol 14, Iss 1, p e1006754 (2018)
In the majority of cases, human immunodeficiency virus type 1 (HIV-1) infection is transmitted through sexual intercourse. A single founder virus in the blood of the newly infected donor emerges from a genetic bottleneck, while in rarer instances mul
Externí odkaz:
https://doaj.org/article/7082ff27c4014f5f90eb047f7e4ce0ef
Autor:
Jennifer Bonogo, Gabrielle Nickel, Nicolas J. Hathaway, David H. Canaday, Richard M. Gibson, David McDonald, Myriam E. Rodriguez, Jeffrey A. Bailey, Denis M. Tebit, Katie Bain, Angel L. Reyes-Rodriguez, Crystal Carpenter, Eric J. Arts
The HIV-1 epidemic originated from a cross-species transmission of a primate lentivirus from chimpanzees to humans near the turn of the 18thcentury. Simian immunodeficiency viruses have been jumping between old world monkeys in West/Central Africa fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa6b7f78ac6356fcab51fef646aec710
https://doi.org/10.1101/2020.10.13.337303
https://doi.org/10.1101/2020.10.13.337303
Autor:
Daniel J. Stieh, Adam Meadows, Yong Gao, Jamie F.S. Mann, Katja Klein, Jeffrey A. Bailey, Immaculate Nankya, Ann M. Carias, Hannah Cheeseman, Thomas J. Hope, Michael A. Lobritz, Gabrielle Nickel, Nicholas J. Hathaway, Annette N. Ratcliff, Eric J. Arts, Robin J. Shattock
Publikováno v:
Journal of Virology
During heterosexual HIV-1 transmission, a genetic bottleneck occurs in the newly infected individual as the virus passes from the mucosa, leading to systemic infection with a single transmitted HIV-1 clone in the recipient. This bottleneck in the rec
Autor:
Korey Demers, Charles S. Morrison, Eric J. Arts, Marshall Munjoma, Peter Mugyenyi, Josaphat Byamugisha, Gabrielle Nickel, Pai Lien Chen, Robert A. Salata, Art F. Y. Poon, Fred Kyeyune, Cynthia Kwok, Katja Klein, Tsungai Chipato, Immaculate Nankya, Emmanuel Ndashimye, Sandra Rwambuya
Publikováno v:
PLoS Pathogens, Vol 14, Iss 1, p e1006754 (2018)
PLoS Pathogens
PLoS Pathogens
In the majority of cases, human immunodeficiency virus type 1 (HIV-1) infection is transmitted through sexual intercourse. A single founder virus in the blood of the newly infected donor emerges from a genetic bottleneck, while in rarer instances mul
Autor:
Marjorie Robert-Guroff, Iart Luca Shytaj, Hye Kyung Chung, Celia C. LaBranche, Eric J. Arts, Anna Teresa Palamara, David C. Montefiori, Ranajit Pal, Mauro Biffoni, Mark G. Lewis, Diego A. Vargas-Inchaustegui, Gabrielle Nickel, Andrea Savarino, Nicholas Farrell, Jonah B. Sacha
Publikováno v:
Journal of Virology. 89:7521-7535
Off-therapy control of viremia by HIV-infected individuals has been associated with two likely players: a restricted viral reservoir and an efficient cell-mediated immune response. We previously showed that a combination of highly suppressive antiret
Autor:
Peter Mugyenyi, Cissy Kityo, Richard M. Gibson, Eva Nabulime, Emmanuel Ndashimye, Miguel E. Quiñones-Mateu, Fred Kyeyune, Gabrielle Nickel, Michael Crawford, Eric J. Arts, Robert A. Salata, Colin Venner, Art F. Y. Poon, Immaculate Nankya
Publikováno v:
Infectious Diseases of Poverty
Infectious Diseases of Poverty, Vol 6, Iss 1, Pp 1-13 (2017)
Infectious Diseases of Poverty, Vol 6, Iss 1, Pp 1-13 (2017)
Background Thymidine analogs, namely AZT (Zidovudine or Retrovir™) and d4T (Stavudine or Zerit™) are antiretroviral drugs still employed in over 75% of first line combination antiretroviral therapy (cART) in Kampala, Uganda despite aversion to pr
Autor:
Eric J. Arts, Srinivas S. Rao, Brennan S. Dirk, Colin Venner, Yong Gao, Mohammed Asmal, Linh Mach, Gabrielle Nickel, Meijuan Tian, Corinne Luedemann, Adam P. Buzby, Jimmy D. Dikeakos, Harikrishnan Balachandran, Norman L. Letvin, Sophie Lane
Publikováno v:
Virology. 499
For studies on vaccines and therapies for HIV disease, SIV-HIV chimeric viruses harboring the HIV-1 env gene (SHIVenv) remain the best virus in non-human primate models. However, there are still very few SHIVenv viruses that can cause AIDS in non-CD8
Autor:
PingfuFu, Shuying Sun, Eric J. Arts, Jonathan Kenyon, David Wald, Yulan Qing, Gabrielle Nickel-Meester, Stanton L. Gerson, Xiaodong Bai, Ellen Drake, Gabriela Santos-Guasch
Publikováno v:
International journal of stem cell research and therapy
Normal human hematopoietic stem and progenitor cells (HPC) lose expression of MLH1, an important mismatch repair (MMR) pathway gene, with age. Loss of MMR leads to replication dependent mutational events and microsatellite instability observed in sec