Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Gabrielle M Siegers"'
Autor:
Tyler T. Cooper, Dylan Z. Dieters-Castator, Jiahui Liu, Gabrielle M. Siegers, Desmond Pink, Lorena Veliz, John D. Lewis, François Lagugné-Labarthet, Yangxin Fu, Helen Steed, Gilles A. Lajoie, Lynne-Marie Postovit
Publikováno v:
Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-20 (2024)
Abstract Background The five-year prognosis for patients with late-stage high-grade serous carcinoma (HGSC) remains dismal, underscoring the critical need for identifying early-stage biomarkers. This study explores the potential of extracellular vesi
Externí odkaz:
https://doaj.org/article/9ae1b15f3d5847c1bbd54eb50095e5a9
Autor:
Julia Schueler, Dagmar Wider, Kerstin Klingner, Gabrielle M Siegers, Annette M May, Ralph Wäsch, Heinz-Herbert Fiebig, Monika Engelhardt
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79939 (2013)
BackgroundWe systematically analyzed multiple myeloma (MM) cell lines and patient bone marrow cells for their engraftment capacity in immunodeficient mice and validated the response of the resulting xenografts to antimyeloma agents.Design and methods
Externí odkaz:
https://doaj.org/article/084d0622fa22403885cc394eda0e439b
Autor:
Daniela F Quail, Guihua Zhang, Logan A Walsh, Gabrielle M Siegers, Dylan Z Dieters-Castator, Scott D Findlay, Heather Broughton, David M Putman, David A Hess, Lynne-Marie Postovit
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48237 (2012)
Breast cancers expressing human embryonic stem cell (hESC)-associated genes are more likely to progress than well-differentiated cancers and are thus associated with poor patient prognosis. Elevated proliferation and evasion of growth control are sim
Externí odkaz:
https://doaj.org/article/7915dbe6ff8a45268257ce18fb1d04f6
Autor:
Gabrielle M Siegers, Tania C Felizardo, A Mark Mathieson, Yoko Kosaka, Xing-Hua Wang, Jeffrey A Medin, Armand Keating
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16700 (2011)
Gamma delta T cells (GDTc) lyse a variety of hematological and solid tumour cells in vitro and in vivo, and are thus promising candidates for cellular immunotherapy. We have developed a protocol to expand human GDTc in vitro, yielding highly cytotoxi
Externí odkaz:
https://doaj.org/article/b6ca6aecb7e84cf49698d16e04dfd348
Autor:
Bruna Victorasso Jardim-Perassi, Pietro Irrera, Oluwaseyi E. Oluwatola, Dominique Abrahams, Veronica C. Estrella, Bryce Ordway, Samantha R. Byrne, Andrew A. Ojeda, Christopher J. Whelan, Jongphil Kim, Matthew S. Beatty, Sultan Damgaci-Erturk, Dario Livio Longo, Kim J. Gaspar, Gabrielle M. Siegers, Barbara A. Centeno, Justin Y. C. Lau, Shari A. Pilon-Thomas, Arig Ibrahim-Hashim, Robert J. Gillies
Publikováno v:
Biomedicines, Vol 12, Iss 2, p 461 (2024)
Acidosis is an important immunosuppressive mechanism that leads to tumor growth. Therefore, we investigated the neutralization of tumor acidity to improve immunotherapy response. L-DOS47, a new targeted urease immunoconjugate designed to neutralize t
Externí odkaz:
https://doaj.org/article/5a610c872c3d4c0c81b99911fe84d7cd
Autor:
Martin Köbel, Lynne-Marie Postovit, Gilles A. Lajoie, Gabrielle M. Siegers, Linda E. Kelemen, Peter F. Rambau, Dylan Z. Dieters-Castator
Workflow, proteins identified, gene ontology, tumour purity, Pearson correlation, staining controls and tissue microarray scoring, Q Exactive Plus results, and HGSC molecular subtype comparison
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ac58b2f028efd1386a649d6ed28437
https://doi.org/10.1158/1078-0432.22472157
https://doi.org/10.1158/1078-0432.22472157
Autor:
Martin Köbel, Lynne-Marie Postovit, Gilles A. Lajoie, Gabrielle M. Siegers, Linda E. Kelemen, Peter F. Rambau, Dylan Z. Dieters-Castator
Purpose:Ovarian carcinomas are a group of distinct diseases classified by histotypes. As histotype-specific treatment evolves, accurate classification will become critical for optimal precision medicine approaches.Experimental Design:To uncover diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4377a403d7dea18afc05a05fbbc784c
https://doi.org/10.1158/1078-0432.c.6528138.v1
https://doi.org/10.1158/1078-0432.c.6528138.v1
Autor:
Martin Köbel, Lynne-Marie Postovit, Gilles A. Lajoie, Gabrielle M. Siegers, Linda E. Kelemen, Peter F. Rambau, Dylan Z. Dieters-Castator
Patient characteristics, instrument settings, protein identifications, staining information, and pathway analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::673a1abb7a56bf6dcdd246fb0583baf4
https://doi.org/10.1158/1078-0432.22472154
https://doi.org/10.1158/1078-0432.22472154
Autor:
Lynne-Marie Postovit, Julia Schueler, Armin M. Gamper, Amirali B. Bukhari, Olena Bilyk, Bahareh Hamedi, Indrani Dutta, Gabrielle M. Siegers, Rojine C. McVea, Catherine J. Field, Jiahui Liu, Marnie Newell
Publikováno v:
Nutrition and Cancer. 74:1431-1445
There is a strong rationale for investigating nutritional interventions with docosahexaenoic acid (DHA) in cancer prevention and therapy; however, the effects of DHA on ovarian cancer (OC) have not...
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2508
CellTrace™ Violet (CTV) is a powerful tool for tracking cell proliferation by permanently binding cellular proteins and rendering the cell fluorescent. After cell division, each daughter cell contains half of the parent cell's fluorescence, enablin