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pro vyhledávání: '"Gabrielle M Sant"'
Autor:
Andrea Cerase, Alexander N. Young, Nerea Blanes Ruiz, Andreas Buness, Gabrielle M. Sant, Mirjam Arnold, Monica Di Giacomo, Michela Ascolani, Manish Kumar, Andreas Hierholzer, Giuseppe Trigiante, Sarah J. Marzi, Philip Avner
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Andrea Cerase et al. report that the chromatin remodeler Chd8 is a key regulator of mammalian Xist expression and therefore X chromosome inactivation. They find that Chd8 activates Xist expression in embryonic stem cells, while in differentiating cel
Externí odkaz:
https://doaj.org/article/d26e720a693341bcb6cd62cfbe1b421b
Autor:
Nerea Blanes Ruiz, Giuseppe Trigiante, Monica Di Giacomo, Alexander N. Young, Gabrielle M Sant, Sarah J. Marzi, Andrea Cerase, Andreas Buness, Andreas Hierholzer, Philip Avner, Manish Kumar, Michela Ascolani, Mirjam Arnold
Publikováno v:
Communications Biology
Communications Biology, 4 (1)
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Communications Biology, 4 (1)
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Female mammals achieve dosage compensation by inactivating one of their two X chromosomes during development, a process entirely dependent on Xist, an X-linked long non-coding RNA (lncRNA). At the onset of X chromosome inactivation (XCI), Xist is up-