Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Gabrielle Lang"'
Publikováno v:
Nature-Based Solutions, Vol 6, Iss , Pp 100197- (2024)
Social contracts are evolving relationships between the government and the public; they describe the rights and responsibilities of each party in catastrophic hydroclimatic events. As the climate crisis unfolds disaster losses continue to increase an
Externí odkaz:
https://doaj.org/article/07ec8d52d4134dfab9c8a4202fa7d942
Autor:
Adrian Constantin Tanjala, Jia Xin Jiang, Paul D. W. Eckford, Mohabir Ramjeesingh, Canhui Li, Ling Jun Huan, Gabrielle Langeveld, Claire Townsend, Daniel V. Paone, Jakob Busch-Petersen, Roman Pekhletski, LiPing Tang, Vamsee Raju, Steven M. Rowe, Christine E. Bear
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Background Cystic Fibrosis causing mutations in the gene CFTR, reduce the activity of the CFTR channel protein, and leads to mucus aggregation, airway obstruction and poor lung function. A role for CFTR in the pathogenesis of other muco-obst
Externí odkaz:
https://doaj.org/article/2da00d71ae6d4c6493740fb315b80270
Autor:
Cesura Andrea, Mosé Da Prada, Urs Röthlisberger, Hans-Werner Lahm, Rene Imhof, J. Gottowik, Gabrielle Lang, Pari Malherbe
Publikováno v:
European Journal of Biochemistry. 236:996-1002
The structural features of the active site of human monoamine oxidase B (MAO-B) were investigated by affinity labeling and site-directed mutagenesis. The pseudosubstrate inhibitor N-[2-aminoethyl]-5-chloro-2-pyridine carboxamide HCl (lazabemide) can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e4e2196353125ea5cb6513b0ac40e9b
https://doi.org/10.1111/j.1432-1033.1996.00996.x
https://doi.org/10.1111/j.1432-1033.1996.00996.x
Publikováno v:
European Journal of Biochemistry. 230:934-942
Monoamine oxidases (MAO) A and B show a high degree of amino acid similarity. Apart from the NH2-terminus, which contains an ADP-binding consensus sequence, little is known about their structural features or the sequences involved in the binding of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d2f8baa32bfc53e1a66a7f1c37863b0
https://doi.org/10.1111/j.1432-1033.1995.tb20639.x
https://doi.org/10.1111/j.1432-1033.1995.tb20639.x
Autor:
Mosé Da Prada, Patrick Caspers, Hans-Werner Lahm, Cesura Andrea, Francis Vilbois, Gabrielle Lang, Catherine Karrer
Publikováno v:
European Journal of Biochemistry. 222:377-386
Technological advances in the field of mass spectrometry (MS) are providing powerful analytical means for the investigation of proteins and peptides. In the present work we have used pneumatically assisted electrospray (ion-spray) MS for the biochemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1bff7d905b41a9551d25ecc20cce6d1
https://doi.org/10.1111/j.1432-1033.1994.tb18876.x
https://doi.org/10.1111/j.1432-1033.1994.tb18876.x
Autor:
Cesura Andrea, Robert Schwarcz, V. Kiefer, M. Da Prada, P. Malherbe, C. Köhler, Gabrielle Lang, Hans-Werner Lahm
Publikováno v:
Journal of Biological Chemistry. 269:13792-13797
Increased cerebral levels of the endogenous excitotoxin quinolinic acid (QUIN) have been speculatively linked to neuronal damage following neurological and inflammatory disorders. 3-Hydroxyanthranilic-acid dioxygenase (3-HAO; 3-hydroxyanthranilate 3,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f95b403b14220a2b5195abbf2f62447
https://doi.org/10.1016/s0021-9258(17)36717-0
https://doi.org/10.1016/s0021-9258(17)36717-0
Publikováno v:
MAO — The Mother of all Amine Oxidases ISBN: 9783211830376
To gain insight into the structure of monoamine oxidases (MAO) A and B, we investigated the properties of various chimaeric enzymes, engineered by moving progressively the junction between the NH2- and the COOH-termini of each MAO form. Whereas excha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60ed57a77a3dc28de09fd5aef27ede82
https://doi.org/10.1007/978-3-7091-6499-0_18
https://doi.org/10.1007/978-3-7091-6499-0_18
Autor:
Pari Malherbe, Rico Buchli, Clemens Broger, Dsniela Alberati-Giani, Gabrielle Lang, C. Köhler, Cesura Andrea, Hans-Werner Lahm
Publikováno v:
European journal of biochemistry. 239(2)
Kynureninase (L-kynurenine hydrolase), a pyridoxal-5'-phosphate-(pyridoxal-P)-dependent enzyme, catalyses the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. In this report, we describ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a22d00690fea0734395627f43e774f4c
https://pubmed.ncbi.nlm.nih.gov/8706755
https://pubmed.ncbi.nlm.nih.gov/8706755
Autor:
Christer Köhler, Cesura Andrea, Hans-Werner Lahm, Daniela Alberati-Giani, Vivian Kiefer, Pari Malherbe, Gabrielle Lang
Publikováno v:
Journal of neurochemistry. 64(4)
In this study, we describe the cloning and characterization of a soluble form of kynurenine aminotransferase (KAT, EC 2.6.1.7) present in rat brain. Soluble KAT was purified from rat kidney and the amino acid sequences of four tryptic peptides determ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::161d9a12d4fa0ec02e434febf91176fc
https://pubmed.ncbi.nlm.nih.gov/7891071
https://pubmed.ncbi.nlm.nih.gov/7891071
Publikováno v:
FEBS letters. 317(1-2)
Monoamine oxidase (MAO)-A and MAO-B are FAD-containing mitochondrial enzymes which catabolize biogenic and xenobiotic amines. The N-terminal regions of both forms of MAO contain an ADP-binding consensus sequence found in several dinucleotide-dependen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6450de8a7d0168f760f2aa61a4373652
https://pubmed.ncbi.nlm.nih.gov/8428624
https://pubmed.ncbi.nlm.nih.gov/8428624